PLEKHN1 and TAX1BP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PLEKHN1	TAX1BP1
Gene Name		pleckstrin homology domain containing, family N member 1	Tax1 (human T-cell leukemia virus type I) binding protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane	Cytosol Extracellular Vesicular Exosome
	Molecular Function		Protein Binding Kinase Binding
	Biological Process		Apoptotic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Type I Interferon Production Negative Regulation Of Apoptotic Process Innate Immune Response
Pathways			RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Negative regulators of RIG-I/MDA5 signaling Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: LPXN LZTS2 REL RFX6 SPERT TAX1BP1 TCF4 TP53BP2 TRAF1 TRIM27	40 interactors: ARHGAP1 CALCOCO2 CNTN2 COG7 CWF19L2 CXXC1 DAZAP2 DSTN EMILIN1 FAM168A FAM189A2 FOXC2 GABARAP IKBKG KIF5B LGALS8 LMO3 MAP1LC3B MAP1LC3C MRPL11 MRPL53 MYO6 NMRK1 ORC5 PLEKHN1 RAB18 RAD18 RIPK1 RNF11 SSX2 STARD13 TBC1D17 TCEA2 TNFAIP3 TNIP1 TNIP3 TRAF6 TSG101 TSHZ3 UBC
Entrez ID		84069	8887
HPRD ID		13190	05618
Ensembl ID		ENSG00000187583	ENSG00000106052
Uniprot IDs		Q494U1	A4D196 B4DSG5 Q86VP1
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Signaling Regulation Of Protein Localization Regulation Of Signal Transduction Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Component Assembly Regulation Of Protein Secretion Protein Complex Assembly Regulation Of Cellular Localization Regulation Of Gene Expression Pancreatic D Cell Differentiation Pancreatic Epsilon Cell Differentiation Regulation Of Nitrogen Compound Metabolic Process Pancreas Development Signal Transduction Transcription, DNA-templated Negative Regulation Of Interleukin-2 Secretion Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cytokine Production RNA Biosynthetic Process Signaling Cell Communication Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Cytokine Production Response To Stimulus Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Protein Transport Regulation Of Secretion Maintenance Of DNA Repeat Elements Regulation Of Establishment Of Protein Localization Regulation Of Cell Death Regulation Of Cellular Process Negative Regulation Of Calcium Ion Import Negative Regulation Of B Cell Receptor Signaling Pathway Embryonic Hindgut Morphogenesis Negative Regulation Of Type B Pancreatic Cell Apoptotic Process Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Insulin Secretion Embryonic Genitalia Morphogenesis Cellular Response To Stimulus Glucose Homeostasis Negative Regulation Of Cytokine Production Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity	Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Toll-like Receptor Signaling Pathway Regulation Of I-kappaB Kinase/NF-kappaB Signaling MyD88-independent Toll-like Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor 4 Signaling Pathway Organelle Disassembly Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling TRIF-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Nucleophagy Immune Response-regulating Signaling Pathway JNK Cascade Cellular Response To Stress Mitochondrion Degradation Regulation Of Vascular Wound Healing Regulation Of Type I Interferon Production Stress-activated MAPK Cascade Negative Regulation Of Intracellular Signal Transduction Stress-activated Protein Kinase Signaling Cascade Regulation Of Intracellular Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Autophagic Vacuole Assembly Positive Regulation Of Immune Response Positive Regulation Of Immune System Process Activation Of MAPK Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Macroautophagy Regulation Of Signaling I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Autophagy Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Protein Processing Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Intracellular Receptor Signaling Pathway Positive Regulation Of Type I Interferon Production Membrane Organization
Tagcloud ?			100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive toxins tumourigenesis
Tagcloud (Difference) ?			100nm 48h 81m anapc13 calm2 carcinogenic diarrheic drawing exhaustive explanation hn1 malat1 mapre2 mllt11 molluscs oa okadaic pathologies poisoning positives pttg1 rodents sga shellfish shsy5y ssh subtractive toxins tumourigenesis
Tagcloud (Intersection) ?