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RBM48 and GLYAT
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
RBM48
GLYAT
Gene Name
RNA binding motif protein 48
glycine-N-acyltransferase
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Mitochondrion
Mitochondrial Matrix
Extracellular Vesicular Exosome
Molecular Function
RNA Binding
Transferase Activity, Transferring Acyl Groups
Glycine N-acyltransferase Activity
Glycine N-benzoyltransferase Activity
Biological Process
Glycine Metabolic Process
Acyl-CoA Metabolic Process
Xenobiotic Metabolic Process
Response To Toxic Substance
Monocarboxylic Acid Metabolic Process
Small Molecule Metabolic Process
Pathways
Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)
Conjugation of salicylate with glycine
Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency)
Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD)
Defective UGT1A4 causes hyperbilirubinemia
Metabolic disorders of biological oxidation enzymes
Conjugation of benzoate with glycine
Phase II conjugation
Conjugation of carboxylic acids
Amino Acid conjugation
Defective UGT1A1 causes hyperbilirubinemia
Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD)
Biological oxidations
Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)
Defective GGT1 causes Glutathionuria (GLUTH)
Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs
Diseases
GWAS
Body mass (lean) (
23108985
)
Protein-Protein Interactions
50 interactors:
ANXA7
APLP1
BID
BTBD2
C11orf49
CCDC106
CDK5RAP2
CDKN1A
CDKN2C
COX17
ERH
FAM118B
FXYD6
GADD45G
GLYAT
GSE1
GSTO1
HSPB1
HSPB3
ID2
KPNA2
MAFG
MAP7D1
MLLT3
MNAT1
MPHOSPH6
NUDT21
OSGEP
PAFAH1B3
PCDHA4
PNP
PPP1R8
PRG2
PSMD11
RAB27A
RFC5
RPA2
SAT1
SERPINB9
SH3GL3
SMN1
SULT1E1
TAF9
TK1
TNFSF10
TRDMT1
TRIB3
VIM
WDR33
ZNF24
5 interactors:
GPRASP1
KRTAP10-8
NOTCH2NL
PTN
RBM48
Entrez ID
84060
10249
HPRD ID
13173
07603
Ensembl ID
ENSG00000127993
ENSG00000149124
Uniprot IDs
B4DGJ6
B7Z2K5
Q5RL73
Q6IB77
PDB IDs
Enriched GO Terms of Interacting Partners
?
Nitrogen Compound Metabolic Process
Mitotic Cell Cycle Phase Transition
G1/S Transition Of Mitotic Cell Cycle
Cell Cycle Phase Transition
Nucleobase-containing Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Developmental Process
Response To Stimulus
Central Nervous System Development
MRNA Polyadenylation
Nucleoside Metabolic Process
Negative Regulation Of Transferase Activity
RNA Polyadenylation
Regulation Of Cell Cycle
Negative Regulation Of Protein Kinase Activity
Regulation Of Mitotic Cell Cycle Phase Transition
Mitotic Cell Cycle
Apoptotic Process
Transcription-coupled Nucleotide-excision Repair
Negative Regulation Of Kinase Activity
Regulation Of Cell Cycle Phase Transition
Response To Stress
Negative Regulation Of Catalytic Activity
Programmed Cell Death
Negative Regulation Of Cellular Protein Metabolic Process
Cell Death
Death
MRNA Processing
Multicellular Organismal Development
Xenobiotic Metabolic Process
Cellular Response To Xenobiotic Stimulus
Cellular Response To DNA Damage Stimulus
Response To Xenobiotic Stimulus
Regulation Of Cellular Protein Metabolic Process
Nervous System Development
Negative Regulation Of Protein Metabolic Process
Anatomical Structure Development
Mitotic Cell Cycle Process
Regulation Of Cell Cycle Process
Cellular Metabolic Process
Negative Regulation Of Protein Phosphorylation
Mitotic G1 DNA Damage Checkpoint
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Cellular Response To Stress
Positive Regulation Of Cell Cycle Arrest
G-protein Coupled Receptor Catabolic Process
Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway
Tagcloud
?
34kda
5mg
acceptor
acceptors
acylglycines
acyltransferase
benzoic
benzoyl
benzoylglycine
carboxylic
coa
conjugates
detoxification
glycine
hippurate
homogeneity
kcat
km
monkey
nickel
ovine
rhesus
salicylic
serving
solve
unanswered
x10
xenobiotic
Tagcloud (Difference)
?
34kda
5mg
acceptor
acceptors
acylglycines
acyltransferase
benzoic
benzoyl
benzoylglycine
carboxylic
coa
conjugates
detoxification
glycine
hippurate
homogeneity
kcat
km
monkey
nickel
ovine
rhesus
salicylic
serving
solve
unanswered
x10
xenobiotic
Tagcloud (Intersection)
?