HIST1H3E and ASF1B

Number of citations of the paper that reports this interaction (PMID 20504901)
112

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		HIST1H3E	ASF1B
Gene Name		histone cluster 1, H3e	anti-silencing function 1B histone chaperone
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromosome Nucleosome Extracellular Region Nucleus Nucleoplasm Membrane Protein Complex Extracellular Vesicular Exosome	Nuclear Chromatin Nucleoplasm Protein Complex
	Molecular Function	DNA Binding Protein Binding Protein Heterodimerization Activity	Protein Binding Histone Binding
	Biological Process	Chromatin Silencing At RDNA Chromatin Organization DNA Replication-dependent Nucleosome Assembly Blood Coagulation Gene Expression DNA Methylation On Cytosine Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Silencing	DNA Replication-dependent Nucleosome Assembly DNA Replication-independent Nucleosome Assembly Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organismal Development Spermatogenesis Chromatin Modification Cell Differentiation
Pathways		RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription Mitotic Prophase PKMTs methylate histone lysines Regulatory RNA pathways RNA Polymerase I Promoter Clearance HDMs demethylate histones Cellular Senescence Signaling by Wnt HATs acetylate histones M Phase Amyloids NoRC negatively regulates rRNA expression RNF mutants show enhanced WNT signaling and proliferation XAV939 inhibits tankyrase, stabilizing AXIN DNA methylation Transcriptional regulation by small RNAs Meiotic recombination HDACs deacetylate histones Chromatin organization misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling RNA Polymerase I Transcription formation of the beta-catenin:TCF transactivating complex Epigenetic regulation of gene expression Senescence-Associated Secretory Phenotype (SASP) Negative epigenetic regulation of rRNA expression Factors involved in megakaryocyte development and platelet production PRC2 methylates histones and DNA Cell Cycle, Mitotic RMTs methylate histone arginines Chromatin modifying enzymes Oxidative Stress Induced Senescence TCF dependent signaling in response to WNT RNA Polymerase I Promoter Opening SIRT1 negatively regulates rRNA Expression Signaling by WNT in cancer Condensation of Prophase Chromosomes
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: ASF1A ASF1B CHAF1A CHAF1B DNMT3A PHF1 RPS6KA5 SETD1B TRIM24 UHRF1	14 interactors: ASF1A C15orf41 CHAF1A CHAF1B H3F3A HCFC1 HIRA HIST1H3C HIST1H3E HIST1H4F HIST4H4 TAF1 TLK1 TLK2
Entrez ID		8353	55723
HPRD ID		11907	16460
Ensembl ID		ENSG00000196966	ENSG00000105011
Uniprot IDs		P68431	Q9NVP2
PDB IDs		1CS9 1CT6 1Q3L 2B2T 2B2U 2B2V 2B2W 2C1J 2C1N 2CV5 2KWJ 2KWK 2L75 2LBM 2M0O 2RI7 2UXN 3A1B 3AFA 3AVR 3AYW 3AZE 3AZF 3AZG 3AZH 3AZI 3AZJ 3AZK 3AZL 3AZM 3AZN 3B95 3KMT 3KQI 3LQI 3LQJ 3O34 3O35 3O37 3RIG 3RIY 3U4S 3U5N 3U5O 3U5P 3UEE 3UEF 3UIG 3UII 3UIK 3V43 3W96 3W97 3W98 3W99 3ZG6 3ZVY 4A0J 4A0N 4A7J 4BD3 4F4U 4F56 4FWF 4HON 4I51
Enriched GO Terms of Interacting Partners?		Chromatin Organization DNA Replication-dependent Nucleosome Assembly Chromosome Organization Chromatin Modification Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Organelle Organization Nucleosome Assembly Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Chromatin Assembly Nucleosome Organization Gene Expression Transcription, DNA-templated Chromatin Assembly Or Disassembly RNA Biosynthetic Process Protein-DNA Complex Assembly DNA Packaging Regulation Of Gene Expression, Epigenetic Nucleobase-containing Compound Metabolic Process DNA Conformation Change RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process DNA Methylation On Cytosine Macromolecule Biosynthetic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Nitrogen Compound Metabolic Process DNA Metabolic Process DNA Repair Biosynthetic Process DNA Replication-independent Nucleosome Assembly Cellular Macromolecular Complex Assembly Negative Regulation Of Gene Expression Cellular Metabolic Process DNA Methylation Positive Regulation Of Histone Modification Negative Regulation Of Gene Expression, Epigenetic Histone H2A-S1 Phosphorylation Histone Modification Methylation Protein Complex Assembly DNA Modification Negative Regulation Of Transcription, DNA-templated	DNA Replication-dependent Nucleosome Assembly Chromatin Organization Protein-DNA Complex Assembly Nucleosome Assembly Chromosome Organization Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly DNA Packaging DNA Conformation Change DNA Methylation On Cytosine Cellular Macromolecular Complex Assembly Chromatin Silencing At RDNA Organelle Organization DNA Replication-independent Nucleosome Assembly Chromatin Silencing DNA Methylation Chromatin Modification Protein Complex Assembly Negative Regulation Of Gene Expression, Epigenetic Regulation Of Gene Expression, Epigenetic DNA Modification Gene Silencing Cellular Component Assembly DNA Metabolic Process Gene Expression Cell Cycle Regulation Of Gene Silencing Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone H4-K20 Demethylation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Methylation Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Response To DNA Damage Stimulus Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Regulation Of Chromatin Assembly Or Disassembly Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Response To Stress
Tagcloud ?			aid avenue caf cenp centromeric chaperones clustering dataset decisions discriminate distinguish exploit guide hierarchical hjurp implicating ki67 luminal offers outperforming p150 p60 regulators substratification tools transcriptome unfavorable unsupervised utilized
Tagcloud (Difference) ?			aid avenue caf cenp centromeric chaperones clustering dataset decisions discriminate distinguish exploit guide hierarchical hjurp implicating ki67 luminal offers outperforming p150 p60 regulators substratification tools transcriptome unfavorable unsupervised utilized
Tagcloud (Intersection) ?