TLR10 and F8A1

Number of citations of the paper that reports this interaction (PMID 16482509)
13

Data Source:
HPRD (two hybrid)

		TLR10	F8A1
Gene Name		toll-like receptor 10	coagulation factor VIII-associated 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Membrane Integral Component Of Membrane	Nucleus
	Molecular Function	Transmembrane Signaling Receptor Activity	Molecular_function
	Biological Process	Toll-like Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Inflammatory Response Immune Response Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Innate Immune Response Regulation Of Cytokine Secretion Positive Regulation Of Inflammatory Response	Biological_process
Pathways		Toll-Like Receptors Cascades Toll Like Receptor 10 (TLR10) Cascade MyD88 cascade initiated on plasma membrane Toll Like Receptor 5 (TLR5) Cascade Innate Immune System
Drugs
Diseases
GWAS		Helicobacter pylori serologic status ( 23652523)
Protein-Protein Interactions		11 interactors: CAT ECH1 F8A1 FLNA FUT7 GLDC LUC7L3 MYD88 PTPN6 TLR1 TLR2	4 interactors: DNMT3A HTT SNTA1 TLR10
Entrez ID		81793	8263
HPRD ID		05884	02374
Ensembl ID		ENSG00000174123	ENSG00000197932
Uniprot IDs		Q9BXR5	P23610
PDB IDs		2J67
Enriched GO Terms of Interacting Partners?		Cellular Response To Triacyl Bacterial Lipopeptide Detection Of Triacyl Bacterial Lipopeptide Response To Molecule Of Fungal Origin Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Cytokine Biosynthetic Process Regulation Of Innate Immune Response Detection Of Bacterial Lipoprotein MyD88-dependent Toll-like Receptor Signaling Pathway Cell Activation Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process Cellular Response To Bacterial Lipopeptide Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Interleukin-6 Production Response To Peptidoglycan Detection Of Molecule Of Bacterial Origin Toll-like Receptor Signaling Pathway Regulation Of Cytokine Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Tumor Necrosis Factor Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Detection Of Bacterium Immune Response-regulating Signaling Pathway Cellular Response To Molecule Of Bacterial Origin Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Growth Of Symbiont In Host Positive Regulation Of Innate Immune Response Detection Of Biotic Stimulus Macrophage Activation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Glycine Metabolic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Platelet Aggregation Positive Regulation Of Immune Response Positive Regulation Of Signal Transduction Positive Regulation Of Transcription Factor Import Into Nucleus Lipopolysaccharide-mediated Signaling Pathway Response To Fungus Immune Response Positive Regulation Of Chemokine Production Regulation Of Chemokine Production Serine Family Amino Acid Metabolic Process Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Innate Immune Response	Neural Plate Formation Regulation Of Vasoconstriction By Circulating Norepinephrine Cellular Response To Acid Chemical Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Regulation Of Protein Phosphatase Type 2A Activity S-adenosylmethioninamine Metabolic Process Hypermethylation Of CpG Island Quinolinate Biosynthetic Process DNA Methylation On Cytosine Within A CG Sequence Negative Regulation Of Synaptic Transmission, Dopaminergic Cellular Modified Amino Acid Metabolic Process Negative Regulation Of Peptidyl-cysteine S-nitrosylation Lactate Biosynthetic Process Regulation Of Membrane Potential Alpha-amino Acid Metabolic Process Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity C-5 Methylation Of Cytosine Paraxial Mesoderm Formation S-adenosylhomocysteine Metabolic Process Quinolinate Metabolic Process Cellular Response To CGMP Methylation-dependent Chromatin Silencing Response To CGMP Serotonin Transport DNA Methylation Involved In Embryo Development Sperm Ejaculation Neural Plate Morphogenesis L-glutamate Import Citrulline Metabolic Process Lactate Metabolic Process Regulation Of Ion Transmembrane Transport Urea Cycle DNA Methylation On Cytosine Neurotransmitter Uptake Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Urea Metabolic Process Cellular Amino Acid Metabolic Process Cellular Response To Organonitrogen Compound Thalamus Development Striatum Development Spermatogenesis Male Gamete Generation Paraxial Mesoderm Morphogenesis Neural Plate Development Amino Acid Import Insemination Regulation Of Synaptic Transmission, Dopaminergic
Tagcloud ?		bewo broadly danger endosomal immunoassay initiating inter multiplex placental proper qpcr respond ten tlr2 tlr3 tlr4 tlr5 tlr6 tlr7 tlr8 tlr9 tlrs toll trimester trophoblast trophoblasts vegfa
Tagcloud (Difference) ?		bewo broadly danger endosomal immunoassay initiating inter multiplex placental proper qpcr respond ten tlr2 tlr3 tlr4 tlr5 tlr6 tlr7 tlr8 tlr9 tlrs toll trimester trophoblast trophoblasts vegfa
Tagcloud (Intersection) ?