TRIM11 and TRIM29

Number of citations of the paper that reports this interaction (PMID 11331580)
291

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TRIM11	TRIM29
Gene Name		tripartite motif containing 11	tripartite motif containing 29
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Cytoplasm Intermediate Filament Cytoskeleton
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Ligase Activity Protein Domain Specific Binding	P53 Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding
	Biological Process	Protein Ubiquitination Negative Regulation Of Viral Transcription Innate Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Viral Entry Into Host Cell Negative Regulation Of Neurogenesis Defense Response To Virus Negative Regulation Of Viral Release From Host Cell	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Negative Regulation Of Protein Localization To Nucleus
Pathways		Antigen processing: Ubiquitination & Proteasome degradation Class I MHC mediated antigen processing & presentation Adaptive Immune System	Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS			Corneal curvature ( 22969067) Stroke (pediatric) ( 22990015)
Protein-Protein Interactions		6 interactors: MED15 PAX6 RNF126 TRIM27 TRIM29 TRIM35	40 interactors: CARD9 CEP70 CRACR2A DMRT1 FBF1 FBXL19 FXR2 GATA1 GCC1 GOLGA2 GTF2E1 HCLS1 HDAC9 HINT1 IKBKG JAKMIP2 KAT5 LZTS2 MAD1L1 MED7 MID2 MLH1 MYO15B PARP1 POLR2D POLR2E PRICKLE3 PRKCA SHOX2 SMAD9 SNAPC1 SP100 TAX1BP3 TRIM11 TRIM23 TRIM27 TRIP6 TSGA10 UBE2I VIM
Entrez ID		81559	23650
HPRD ID		07429	10280
Ensembl ID		ENSG00000154370	ENSG00000137699
Uniprot IDs		Q96F44	B7Z8U9 E9PRL4 Q14134
PDB IDs			2CSV
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Viral Release From Host Cell Regulation Of Viral Release From Host Cell Protein K63-linked Ubiquitination Retrograde Transport, Endosome To Golgi Negative Regulation Of Viral Process Pancreatic A Cell Development Forebrain-midbrain Boundary Formation Regulation Of Transcription From RNA Polymerase II Promoter Involved In Somatic Motor Neuron Fate Commitment Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-2 Secretion Positive Regulation Of Glucagon Secretion Regulation Of Viral Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Rhombomere Morphogenesis Protein Polyubiquitination Transcription From RNA Polymerase II Promoter Regulation Of Asymmetric Cell Division Regulation Of Transcription From RNA Polymerase II Promoter Involved In Spinal Cord Motor Neuron Fate Specification Positive Regulation Of Cell Fate Specification Transcription, DNA-templated Endosomal Transport Regulation Of Transcription From RNA Polymerase II Promoter Involved In Ventral Spinal Cord Interneuron Specification RNA Biosynthetic Process Pancreatic A Cell Differentiation Negative Regulation Of Calcium Ion Import Somatic Motor Neuron Differentiation Regulation Of Cellular Localization Stem Cell Development Forebrain Anterior/posterior Pattern Specification Cerebral Cortex Regionalization Negative Regulation Of Transcription, DNA-templated Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Forebrain Dorsal/ventral Pattern Formation Regulation Of Glucagon Secretion Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Interferon-gamma Secretion Oligodendrocyte Cell Fate Specification Lacrimal Gland Development Iris Morphogenesis Cornea Development In Camera-type Eye Rhombomere Development Stem Cell Differentiation Insulin Metabolic Process Negative Regulation Of Protein Phosphorylation Formation Of Anatomical Boundary Cellular Response To Prostaglandin E Stimulus	Regulation Of Viral Transcription Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Viral Transcription Negative Regulation Of Cellular Metabolic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Viral Process Regulation Of Viral Process Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Gene Expression Negative Regulation Of Viral Release From Host Cell Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression RNA Metabolic Process Immune System Process Intracellular Signal Transduction Positive Regulation Of Cellular Biosynthetic Process Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Process Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Differentiation Regulation Of Cellular Localization Regulation Of Protein Localization DNA-templated Transcription, Initiation Innate Immune Response Organelle Organization Regulation Of Signal Transduction Cellular Macromolecule Biosynthetic Process Spindle Midzone Assembly Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Process Positive Regulation Of Signal Transduction Transcription Elongation From RNA Polymerase II Promoter Response To Stress Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Tagcloud ?		adaptor antiviral cc cc2 collectively constitutively conversely defense dimerization ectopic ifnalpha ifnbeta infectivity innate interacted interferons irf3 knockdown mavs nap1 opposite phosphorylates rig sintbad tank tbk1 tightly traf tripartite	adenocarcinoma ataxia atdc atm basis candidacy damaging directly ductal improve ionizing leading mapkap mk2 pancreatic pdac phosphorylated poorly radiation radioprotective radioresistance radiosensitize repair ser ser550 telangiectasia therapeutic understood xenograft
Tagcloud (Difference) ?		adaptor antiviral cc cc2 collectively constitutively conversely defense dimerization ectopic ifnalpha ifnbeta infectivity innate interacted interferons irf3 knockdown mavs nap1 opposite phosphorylates rig sintbad tank tbk1 tightly traf tripartite	adenocarcinoma ataxia atdc atm basis candidacy damaging directly ductal improve ionizing leading mapkap mk2 pancreatic pdac phosphorylated poorly radiation radioprotective radioresistance radiosensitize repair ser ser550 telangiectasia therapeutic understood xenograft
Tagcloud (Intersection) ?