CDK2AP1 and ZNF420

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CDK2AP1	ZNF420
Gene Name		cyclin-dependent kinase 2 associated protein 1	zinc finger protein 420
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Perinuclear Region Of Cytoplasm	Nucleus Extracellular Vesicular Exosome
	Molecular Function	DNA Polymerase Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation DNA-dependent DNA Replication Cell Cycle	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: CCDC136 CDK2 CDK2AP2 MRFAP1L1 POLA1 ZNF420	8 interactors: CDC42 CDK2AP1 CYP4V2 CYP51A1 HAX1 SLC1A7 TNFRSF1B TRIM28
Entrez ID		8099	147923
HPRD ID		03726	08122
Ensembl ID		ENSG00000111328	ENSG00000197050
Uniprot IDs		O14519	Q8TAQ5
PDB IDs		2KW6
Enriched GO Terms of Interacting Partners?		G1/S Transition Of Mitotic Cell Cycle Leading Strand Elongation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition DNA Replication Positive Regulation Of DNA-dependent DNA Replication Initiation Lagging Strand Elongation Regulation Of DNA-dependent DNA Replication Initiation DNA Replication, Synthesis Of RNA Primer Cellular Response To Nitric Oxide DNA Repair Positive Regulation Of DNA-dependent DNA Replication Response To Nitric Oxide Mitotic Cell Cycle Process Telomere Maintenance Via Semi-conservative Replication Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Regulation Of Gene Silencing Double-strand Break Repair Via Nonhomologous End Joining Nuclear DNA Replication Telomere Maintenance Via Recombination Cellular Response To Reactive Nitrogen Species Mitotic Cell Cycle Cellular Macromolecule Biosynthetic Process Mitotic Recombination DNA Strand Elongation Involved In DNA Replication Cellular Response To DNA Damage Stimulus DNA Strand Elongation Macromolecule Biosynthetic Process Telomere Maintenance Via Telomere Lengthening DNA Replication Initiation Centrosome Duplication Histone Phosphorylation Chromosome Organization Cell Cycle Process DNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Centrosome Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Nucleobase-containing Compound Metabolic Process Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of DNA Replication Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process	Regulation Of Intracellular Protein Transport Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Intracellular Transport Cholesterol Biosynthetic Process Via 24,25-dihydrolanosterol Positive Regulation Of Protein Metabolic Process Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Cellular Metabolic Process Negative Regulation Of DNA Demethylation Positive Regulation Of Hair Follicle Cell Proliferation Fatty Acid Omega-oxidation Regulation Of Protein Transport Actin Filament Branching Submandibular Salivary Gland Formation Positive Regulation Of DNA Metabolic Process Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Targeting To Mitochondrion Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Positive Regulation Of Protein Phosphorylation Convergent Extension Involved In Axis Elongation Regulation Of Protein Localization Establishment Of Golgi Localization Regulation Of Genetic Imprinting DNA Methylation Involved In Embryo Development Positive Regulation Of Metalloenzyme Activity Positive Regulation Of Phosphorylation Positive Regulation Of Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Intracellular Transport Neuron Fate Determination Epithelial-mesenchymal Cell Signaling Positive Regulation Of Granulocyte Differentiation Regulation Of Protein Heterodimerization Activity Regulation Of Mitochondrion Degradation Keratinocyte Development Regulation Of Synapse Structural Plasticity Regulation Of Protein Metabolic Process Regulation Of Cellular Localization Regulation Of Protein Phosphorylation Positive Regulation Of Pseudopodium Assembly Nuclear Migration RNA Destabilization Cardiac Conduction System Development Convergent Extension Positive Regulation Of Membrane Protein Ectodomain Proteolysis Golgi Localization Negative Regulation Of Viral Release From Host Cell
Tagcloud ?		adh6 aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Difference) ?		adh6 aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Intersection) ?