CDK5RAP3 and FKBP6

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CDK5RAP3	FKBP6
Gene Name		CDK5 regulatory subunit associated protein 3	FK506 binding protein 6, 36kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Endomembrane System Membrane Protein Complex	Synaptonemal Complex Cytoplasm Endoplasmic Reticulum Membrane Cytosol
	Molecular Function	Protein Binding Protein Kinase Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Hsp90 Protein Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Mitotic Cell Cycle Brain Development Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Ufmylation	Protein Peptidyl-prolyl Isomerization Protein Folding Meiotic Nuclear Division Spermatogenesis Cell Differentiation Gene Silencing By RNA PiRNA Metabolic Process DNA Methylation Involved In Gamete Generation Chaperone-mediated Protein Folding
Pathways			PIWI-interacting RNA (piRNA) biogenesis Regulatory RNA pathways Meiotic synapsis
Drugs
Diseases
GWAS		Epilepsy (generalized) ( 22949513)	Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Protein-Protein Interactions		11 interactors: CDK5R1 CREBBP CRMP1 DGCR14 DISC1 FKBP6 KPNA2 SRPRB TAB1 TAX1BP3 TSPYL4	10 interactors: ACD CCDC36 CCNK CDK5RAP3 GAPDH HSP90AA1 LZTS2 NME7 SUMO1P1 TINF2
Entrez ID		80279	8468
HPRD ID		12190	05326
Ensembl ID		ENSG00000108465	ENSG00000077800
Uniprot IDs		B7Z6N4 F5H3I5 Q96JB5	G3V0I2 O75344 Q7Z4T4
PDB IDs			3B7X
Enriched GO Terms of Interacting Partners?		Cerebral Cortex Radially Oriented Cell Migration Positive Regulation Of Protein Modification Process Cerebral Cortex Cell Migration Superior Olivary Nucleus Maturation Telencephalon Cell Migration Forebrain Cell Migration Positive Regulation Of Protein Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Kinase Activity Cell Surface Receptor Signaling Pathway Pons Maturation N-terminal Peptidyl-lysine Acetylation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transferase Activity Positive Regulation Of Metabolic Process Serine Phosphorylation Of STAT3 Protein Cerebral Cortex Development Germ-line Stem Cell Maintenance Serine Phosphorylation Of STAT Protein Neuron Migration Signal Transduction Pyrimidine Nucleobase Catabolic Process Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Catalytic Activity Negative Regulation Of Protein Localization To Cell Surface Activation Of MAPKKK Activity Pallium Development Regulation Of Protein Kinase Activity	Telomere Assembly Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Organelle Organization Regulation Of Telomere Maintenance Protein Localization To Chromosome Negative Regulation Of DNA Replication Telomere Maintenance Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of Single-stranded Telomeric DNA Binding Peptidyl-cysteine S-trans-nitrosylation Negative Regulation Of Chromosome Organization Negative Regulation Of DNA Metabolic Process Cellular Localization Protein Localization To Organelle Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cellular Protein Localization Regulation Of Protein ADP-ribosylation Regulation Of DNA Replication Intracellular Transport Positive Regulation Of DNA Metabolic Process Mitotic Cell Cycle Process Multicellular Organismal Development Protein Import Into Mitochondrial Outer Membrane Negative Regulation Of Protein Glycosylation Anatomical Structure Development Mitotic Cell Cycle Peptidyl-cysteine S-nitrosylation Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway Protection From Non-homologous End Joining At Telomere Microtubule-based Process Telomere Capping Regulation Of Chromosome Organization Cellular Component Assembly Positive Regulation Of Telomerase Activity Protein Localization Regulation Of Cellular Protein Metabolic Process Establishment Of Localization In Cell Developmental Process Protein Ufmylation Spindle Midzone Assembly Regulation Of Protein Glycosylation Regulation Of Protein Metabolic Process Positive Regulation Of Telomere Maintenance Cell Cycle Process Regulation Of Cellular Process Microtubule Severing Negative Regulation Of Glycoprotein Metabolic Process
Tagcloud ?		anchors aspartate ataxin atx1 autonomous bergmann cerebellum collectively consistently downregulated eventually glia glutamate helix interacting knockin maxer mediates mediating mutant named purkinje represses repression rescues sca1 strengthened transporter vulnerability	biogenesis chaperone client duplicated encoded germ homolog hsp90 hsp90alpha isofom kingdoms knockout l1 mammals mislocalization miwi2 nucleotides paralogs pirna pirnas piwi retrotransposon retrotransposons rnas specialized testes transposon unchanged vertebrates
Tagcloud (Difference) ?		anchors aspartate ataxin atx1 autonomous bergmann cerebellum collectively consistently downregulated eventually glia glutamate helix interacting knockin maxer mediates mediating mutant named purkinje represses repression rescues sca1 strengthened transporter vulnerability	biogenesis chaperone client duplicated encoded germ homolog hsp90 hsp90alpha isofom kingdoms knockout l1 mammals mislocalization miwi2 nucleotides paralogs pirna pirnas piwi retrotransposon retrotransposons rnas specialized testes transposon unchanged vertebrates
Tagcloud (Intersection) ?