CEP63 and TSHZ3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CEP63	TSHZ3
Gene Name		centrosomal protein 63kDa	teashirt zinc finger homeobox 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Centrosome Centriole Cytosol	Nucleus Nucleoplasm Mitochondrion Growth Cone
	Molecular Function	Protein Binding	DNA Binding Chromatin Binding Protein Binding Metal Ion Binding
	Biological Process	DNA Damage Checkpoint G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Mitotic Nuclear Division Centriole Replication Signal Transduction In Response To DNA Damage Spindle Assembly Cell Division	Metanephros Development Ureteric Bud Development In Utero Embryonic Development Regulation Of Respiratory Gaseous Exchange By Neurological System Process Transcription, DNA-templated Lung Development Negative Regulation Of Transcription, DNA-templated Musculoskeletal Movement Sensory Perception Of Touch Positive Regulation Of Smooth Muscle Cell Differentiation Kidney Morphogenesis Ureteric Peristalsis Ureter Smooth Muscle Cell Differentiation Kidney Smooth Muscle Cell Differentiation
Pathways		Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS		Height ( 18391952)	Cognitive performance ( 19734545) Phospholipid levels (plasma) ( 21829377)
Protein-Protein Interactions		44 interactors: ALOX5 ARFIP2 ARNT2 CAMKK2 CCDC14 CCNI CEP57 CEP57L1 DDX26B DISC1 DST DTNB DZIP3 EXOC4 EZH2 FAM161A FBF1 GSE1 HAUS1 KXD1 MACF1 MBIP NCOR2 NDEL1 NXT2 PCNXL4 POLR3C PPP1R13B PPP4R1 SMARCE1 SMC3 SNRNP70 SPTAN1 SPTBN1 SSX3 SYNE1 SYT17 TANK TBC1D15 TSHZ3 TXLNA TXLNB USHBP1 ZCCHC10	16 interactors: APBB1 CCDC155 CEP63 CEP70 CTBP1 CTBP2 KRT40 MAD1L1 MTUS2 SPAG5 TAX1BP1 TFIP11 TRAF2 TRIM23 TRIM27 TRIM54
Entrez ID		80254	57616
HPRD ID		07826	18351
Ensembl ID		ENSG00000182923	ENSG00000121297
Uniprot IDs		Q96MT8	Q63HK5
PDB IDs			2DMI
Enriched GO Terms of Interacting Partners?		Microtubule Cytoskeleton Organization Organelle Organization Cytoskeleton Organization Microtubule-based Process Cell Cycle Process Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Cell Cycle Cellular Localization Golgi To Plasma Membrane Protein Transport Cell Cycle Maintenance Of Protein Location In Cell Maintenance Of Protein Location Brain Development Maintenance Of Location In Cell Protein Localization To Organelle Head Development Anatomical Structure Development Golgi To Plasma Membrane Transport Regulation Of Cellular Component Size Positive Regulation Of Axon Extension Intermediate Filament Cytoskeleton Organization Microtubule Anchoring Protein Localization Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Regulation Of Cellular Ketone Metabolic Process By Negative Regulation Of Transcription From RNA Polymerase II Promoter Leukotriene Production Involved In Inflammatory Response Kidney Smooth Muscle Cell Differentiation Ureteric Peristalsis Nervous System Development Intermediate Filament-based Process Positive Regulation Of Cell Morphogenesis Involved In Differentiation Protein Localization To Nucleus Regulation Of Cell Cycle Cell Proliferation In Forebrain Actin Filament Capping Central Nervous System Development Mitotic Cell Cycle Process Cellular Protein Localization Cerebral Cortex Radially Oriented Cell Migration Endomembrane System Organization Negative Regulation Of Actin Filament Depolymerization Developmental Process	Cell Cycle Process White Fat Cell Differentiation Cell Cycle Viral Genome Replication Regulation Of Organelle Organization Organelle Organization Protein K63-linked Ubiquitination Protein Trimerization Regulation Of Cellular Component Organization Mitotic Cell Cycle Process Regulation Of Metaphase Plate Congression Chromosome Localization To Nuclear Envelope Involved In Synapsis Spliceosomal Complex Disassembly Negative Regulation Of Transcription From RNA Polymerase II Promoter By Histone Modification Negative Regulation Of Thymidylate Synthase Biosynthetic Process Mitotic Cell Cycle Mitotic Nuclear Division Regulation Of Chromosome Segregation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Chromosome Organization Negative Regulation Of Interleukin-2 Secretion Negative Regulation Of Protein Metabolic Process Cell Division G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Binding Chromosome Organization Regulation Of Cellular Localization Fat Cell Differentiation Spindle Organization Regulation Of Cytoskeleton Organization Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Regulation Of Microtubule Cytoskeleton Organization Double-strand Break Repair Negative Regulation Of Calcium Ion Import Positive Regulation Of Chromatin Binding Regulation Of Cytokine Production Viral Process Negative Regulation Of Glial Cell Apoptotic Process Protein Ubiquitination Regulation Of Microtubule-based Process Protein Polyubiquitination Protein Modification By Small Protein Conjugation Interferon-gamma Secretion Viral Life Cycle Negative Regulation Of Histone H4 Acetylation Regulation Of Adaptive Immune Response Regulation Of Chromosome Organization Positive Regulation Of Protein Homodimerization Activity Regulation Of Protein Metabolic Process Regulation Of Transcription, DNA-templated
Tagcloud ?			chip deep dysregulated dysregulation h3k27me3 homeobox hox hoxb7 hoxc10 hoxc13 hoxd8 irx1 irx4 keratinocytes mark neoplastic okf6 oncomine polycomb prc prc2 repressive rnaseq scc six2 suz12 tert1r transcripts tumorigenic
Tagcloud (Difference) ?			chip deep dysregulated dysregulation h3k27me3 homeobox hox hoxb7 hoxc10 hoxc13 hoxd8 irx1 irx4 keratinocytes mark neoplastic okf6 oncomine polycomb prc prc2 repressive rnaseq scc six2 suz12 tert1r transcripts tumorigenic
Tagcloud (Intersection) ?