ARHGEF5 and ATP13A1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ARHGEF5	ATP13A1
Gene Name		Rho guanine nucleotide exchange factor (GEF) 5	ATPase type 13A1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Rho Guanyl-nucleotide Exchange Factor Activity Protein Binding GTP Binding	Molecular_function ATP Binding ATPase Activity Metal Ion Binding
	Biological Process	Myeloid Dendritic Cell Chemotaxis Actin Cytoskeleton Organization Regulation Of Rho GTPase Activity Positive Regulation Of Rho GTPase Activity Intracellular Signal Transduction Positive Regulation Of Podosome Assembly	Cation Transport Biological_process Metabolic Process
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23535729)
Protein-Protein Interactions		15 interactors: APP ATP13A1 CALCOCO2 CCNE1 CHPF CRKL EFHC2 FKBP8 GRB2 HSPBAP1 NR4A1 PLCG1 SEPHS2 TRIM27 TRIM54	2 interactors: ARHGEF5 GLP1R
Entrez ID		7984	57130
HPRD ID		02932	12501
Ensembl ID		ENSG00000050327	ENSG00000105726
Uniprot IDs		Q12774	Q9HD20
PDB IDs
Enriched GO Terms of Interacting Partners?		Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Regulation Of Protein Kinase Activity Immune Response Regulation Of Phosphorylation Defense Response Regulation Of Kinase Activity Immune System Process Regulation Of Phosphorus Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Intracellular Receptor Signaling Pathway Viral Process Regulation Of Protein Phosphorylation Cellular Response To Growth Factor Stimulus Fc-epsilon Receptor Signaling Pathway Chemotaxis Response To Growth Factor Regulation Of Cellular Protein Metabolic Process Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Fc Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway Regulation Of Protein Metabolic Process Selenocysteine Biosynthetic Process Activation Of MAPKK Activity Signaling Cell Communication Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Catalytic Activity Regulation Of ERBB Signaling Pathway Regulation Of Immune Response Immune Response-regulating Cell Surface Receptor Signaling Pathway Response To Stress Enzyme Linked Receptor Protein Signaling Pathway Axon Guidance Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Selenium Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Blood Coagulation Hemostasis Positive Regulation Of Actin Filament Polymerization Collateral Sprouting In Absence Of Injury Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Polymerization	Myeloid Dendritic Cell Chemotaxis Positive Regulation Of Podosome Assembly Regulation Of Podosome Assembly Dendritic Cell Chemotaxis CAMP-mediated Signaling Dendritic Cell Migration Positive Regulation Of Organelle Assembly Activation Of Adenylate Cyclase Activity Cyclic-nucleotide-mediated Signaling Positive Regulation Of Adenylate Cyclase Activity Cellular Response To Glucagon Stimulus Positive Regulation Of Lyase Activity Positive Regulation Of Catalytic Activity Response To Glucagon Regulation Of Adenylate Cyclase Activity Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Intracellular Signal Transduction Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Leukocyte Chemotaxis Regulation Of Catalytic Activity Energy Reserve Metabolic Process Second-messenger-mediated Signaling Positive Regulation Of Cytosolic Calcium Ion Concentration Regulation Of Heart Contraction Cell Chemotaxis Positive Regulation Of Protein Complex Assembly Cytosolic Calcium Ion Homeostasis
Tagcloud ?			adult atpases brainstem cerebellum cerebral constant cortex currently differentially eukaryotes fairly furthers hippocampus isoforms nervous neurogenesis organogenesis p5 peak playing poorly predominant regions similarly summary
Tagcloud (Difference) ?			adult atpases brainstem cerebellum cerebral constant cortex currently differentially eukaryotes fairly furthers hippocampus isoforms nervous neurogenesis organogenesis p5 peak playing poorly predominant regions similarly summary
Tagcloud (Intersection) ?