KCTD17 and LRRC18

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		KCTD17	LRRC18
Gene Name		potassium channel tetramerization domain containing 17	leucine rich repeat containing 18
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm
	Molecular Function	Protein Binding Identical Protein Binding
	Biological Process	Protein Homooligomerization
Pathways
Drugs
Diseases
GWAS		Red blood cell traits ( 23222517)	Subclinical atherosclerosis traits (other) ( 17903303) Systemic lupus erythematosus ( 19838193)
Protein-Protein Interactions		12 interactors: AQP1 DMC1 LNX1 LRRC18 NIF3L1 NUDT18 PSMA1 RWDD4 STK16 SUV39H2 TINF2 TUBGCP4	1 interactors: KCTD17
Entrez ID		79734	474354
HPRD ID		07764	17450
Ensembl ID		ENSG00000100379	ENSG00000165383
Uniprot IDs		Q8N5Z5	Q8N456
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Male Meiosis Negative Regulation Of Protein ADP-ribosylation Metanephric Descending Thin Limb Development DGDP Catabolic Process Metanephric Proximal Straight Tubule Development Metanephric Proximal Convoluted Tubule Segment 2 Development DADP Catabolic Process Maintenance Of Symbiont-containing Vacuole By Host Transepithelial Water Transport GDP Catabolic Process Response To Brefeldin A Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Regulation Of Protein ADP-ribosylation Carbon Dioxide Transmembrane Transport Corticotropin Secretion 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Establishment Or Maintenance Of Actin Cytoskeleton Polarity Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Response To Oxygen Levels Metanephric Proximal Convoluted Tubule Development Nitric Oxide Transport Dihydrobiopterin Metabolic Process Cellular Response To Mercury Ion Cell Cycle Metanephric Proximal Tubule Development Negative Regulation Of Protein Glycosylation Renal Water Absorption Histone H3-K9 Dimethylation Positive Regulation Of Saliva Secretion Carbon Dioxide Transport Epithelial Fluid Transport Meiotic Nuclear Division Protein Localization To Chromosome, Telomeric Region Purine Ribonucleoside Diphosphate Catabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Renal Water Transport Cellular Response To Copper Ion Nucleobase-containing Small Molecule Catabolic Process Pancreatic Juice Secretion Telomere Assembly Proximal Tubule Development Regulation Of Saliva Secretion Cellular Metabolic Process Ribonucleoside Diphosphate Catabolic Process Metanephric Loop Of Henle Development Cerebrospinal Fluid Secretion
Tagcloud ?		57r arrests aurora axoneme centriolar centrioles cilia ciliary ciliogenesis crl3 crl3s cul3 developments doublet exit extension initiate instructive k50 ligases mother multistep organelles organize polyubiquitylates removes stepped trichoplein ubiquitylatable
Tagcloud (Difference) ?		57r arrests aurora axoneme centriolar centrioles cilia ciliary ciliogenesis crl3 crl3s cul3 developments doublet exit extension initiate instructive k50 ligases mother multistep organelles organize polyubiquitylates removes stepped trichoplein ubiquitylatable
Tagcloud (Intersection) ?