PTP4A1 and ATF7

Number of citations of the paper that reports this interaction (PMID 11278933)
21

Data Source:
HPRD (two hybrid, in vivo)

		PTP4A1	ATF7
Gene Name		protein tyrosine phosphatase type IVA, member 1	activating transcription factor 7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Early Endosome Endoplasmic Reticulum Spindle Cytoplasmic Side Of Plasma Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytoplasm Nuclear Periphery
	Molecular Function	Protein Tyrosine Phosphatase Activity	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Enzyme Binding Sequence-specific DNA Binding Metal Ion Binding Mitogen-activated Protein Kinase Binding
	Biological Process	Cell Cycle Multicellular Organismal Development Positive Regulation Of Cell Migration Peptidyl-tyrosine Dephosphorylation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription, DNA-templated Viral Process
Pathways
Drugs
Diseases
GWAS			Height ( 21998595 20189936)
Protein-Protein Interactions		6 interactors: APP ATF7 CREB3L2 GNL1 TUBA1B ZNF212	16 interactors: ATF2 CCDC155 FAM9B FCER2 FOS MAPK9 MITD1 OCIAD1 PTP4A1 PTP4A2 TAF12 TAF4 TAOK3 TMEM239 URI1 YY1
Entrez ID		7803	11016
HPRD ID		03349	06968
Ensembl ID		ENSG00000112245	ENSG00000170653
Uniprot IDs		Q93096	P17544
PDB IDs		1RXD 1XM2
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Cytoskeleton-dependent Intracellular Transport	Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Transcription From RNA Polymerase II Promoter Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MAPK Cascade MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Signal Transduction By Phosphorylation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Cellular Response To Stress Positive Regulation Of Innate Immune Response Regulation Of Innate Immune Response Positive Regulation Of Immune Response Cellular Response To UV Cell Cycle Transcription Elongation From RNA Polymerase II Promoter Chromosome Localization To Nuclear Envelope Involved In Synapsis Apoptotic Mitochondrial Changes Response To Light Stimulus Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cellular Response To DNA Damage Stimulus Response To Lipid Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Immune Response DNA-templated Transcription, Elongation Positive Regulation Of Immune System Process Positive Regulation Of Transforming Growth Factor Beta2 Production Response To Prostaglandin F Cellular Response To Light Stimulus Mitotic DNA Damage Checkpoint Heterocycle Metabolic Process
Tagcloud ?		altered collectively component depleted displayed hoxa4 id2 id4 invasion invasive knockdown led lung med1 mediator metastasis microarray migration modulating nsclc pkp3 pld1 rgs2 strongly tgm2 timp2 trap220 upar xenograft	akap6 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Difference) ?		altered collectively component depleted displayed hoxa4 id2 id4 invasion invasive knockdown led lung med1 mediator metastasis microarray migration modulating nsclc pkp3 pld1 rgs2 strongly tgm2 timp2 trap220 upar xenograft	akap6 atxn1 bmpr2 categorize deltan eef1a1 grip2 gtf2f1 interactors jbd jbds jnk1alpha1 jnk3 jnk3alpha1 jnks kcne4 myo9b nnat pias1 ptgds ptpn2 rabgap1 rusc2 shank1 sumo1 sypl1 tkt topbp1 znf668
Tagcloud (Intersection) ?