MKRN3 and TRIM34

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		MKRN3	TRIM34
Gene Name		makorin ring finger protein 3	tripartite motif containing 34
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ribonucleoprotein Complex	Cytoplasm Cytosol
	Molecular Function	Protein Binding Zinc Ion Binding Ligase Activity	Molecular_function Zinc Ion Binding
	Biological Process	Protein Ubiquitination	Cytokine-mediated Signaling Pathway Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Protein Trimerization
Pathways			Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS
Protein-Protein Interactions		55 interactors: ANKRD11 BEX2 CRACR2A ENKD1 ERCC1 FAM110A FAM124B FARS2 KIF1A LRSAM1 MDM2 MDM4 MEOX2 MNAT1 MRPS6 NABP1 NDE1 PEX10 PEX5 PRPF31 PSMA1 RBM41 RNF166 RNF32 RNF7 SCNM1 SF1 SFN TCEA2 TCHP TFAP2A TRIM23 TRIM31 TRIM34 TRIM5 TRIM65 TRIM8 TSG101 TTC25 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2L3 UBE2N UBE2U UBE2V1 UBE2V2 UBE2W	7 interactors: BIRC2 MKRN3 MNAT1 TRIM5 UBE2K UBE2U USP2
Entrez ID		7681	53840
HPRD ID		04836	16141
Ensembl ID		ENSG00000179455	ENSG00000258659
Uniprot IDs		Q13064	Q9BYJ4
PDB IDs			2EGP
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K48-linked Ubiquitination Protein K11-linked Ubiquitination Cellular Macromolecule Catabolic Process Protein K63-linked Ubiquitination Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Modification Process Cellular Protein Metabolic Process Cellular Response To Stress Catabolic Process Cellular Response To DNA Damage Stimulus Protein Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Metabolic Process Response To Stress Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Positive Regulation Of Ubiquitin-protein Transferase Activity Activation Of Innate Immune Response Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Proteolysis Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Cycle Cellular Response To Hypoxia Positive Regulation Of Innate Immune Response Cellular Response To Decreased Oxygen Levels DNA Repair Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Innate Immune Response Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cell Cycle Process Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Protein Ubiquitination Cell Cycle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Innate Immune Response Regulation Of Viral Entry Into Host Cell Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Protein Catabolic Process Viral Process	Protein Polyubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Modification Process Cellular Macromolecule Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cellular Protein Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Protein Metabolic Process Catabolic Process Positive Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Monoubiquitination Positive Regulation Of Protein K48-linked Ubiquitination Proteolysis Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Proteolysis Activation Of Innate Immune Response Regulation Of Viral Process Response To Stress Regulation Of Protein Monoubiquitination Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Innate Immune Response Regulation Of Cellular Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein K63-linked Ubiquitination Regulation Of Cell Cycle Regulation Of I-kappaB Kinase/NF-kappaB Signaling Regulation Of Protein Metabolic Process Regulation Of Innate Immune Response Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Complex Assembly Locomotor Rhythm Cellular Metabolic Process Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Negative Regulation Of Necroptotic Process Negative Regulation Of Necrotic Cell Death Regulation Of RIG-I Signaling Pathway Regulation Of Necroptotic Process Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Viral Entry Into Host Cell Adult Heart Development Circadian Behavior Regulation Of Protein Catabolic Process
Tagcloud ?			ancestral coding divergent duplication evolutionary exaggerated exaptation existed haplorhini insertions interspecies intron introns ltr ltrs possessing pressures primates prosimian replacements retroviral synonymous transposable trim22 trim5 trim6 undergone unrecognized
Tagcloud (Difference) ?			ancestral coding divergent duplication evolutionary exaggerated exaptation existed haplorhini insertions interspecies intron introns ltr ltrs possessing pressures primates prosimian replacements retroviral synonymous transposable trim22 trim5 trim6 undergone unrecognized
Tagcloud (Intersection) ?