MZF1 and LDOC1

Number of citations of the paper that reports this interaction (PMID 15670815)
8

Data Source:
HPRD (in vitro, two hybrid)

		MZF1	LDOC1
Gene Name		myeloid zinc finger 1	leucine zipper, down-regulated in cancer 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleolus
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Transcription Regulatory Region DNA Binding Metal Ion Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Negative Regulation Of Cell Proliferation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CDK4 CDK6 FHL3 LDOC1 SCAND1 ZNF174 ZNF202 ZNF24	62 interactors: AATF ABLIM1 AEBP2 AES AP1M1 ATF4 ATP6V1G1 BARD1 C1orf109 CCDC33 CCDC85B CEBPE CTNNBL1 DPF2 DPPA4 FAM107A FAM193B FAM208B FAM50B FAM90A1 FOSL1 FXR2 GNL3L HAUS1 HDAC4 HGS IKZF5 INPP1 KRT15 KRT18 LATS1 LENG1 LNX1 MEAF6 MFAP1 MYC MZF1 NRIP1 NXF1 PEG10 PLEKHF2 POLL PRPF31 PSMA1 PSMF1 RAB29 SDCBP SETD5 SH2D4A SMARCD1 TBC1D7 TMSB4XP1 TNNT1 TTC23 UTP14A ZBTB16 ZBTB24 ZGPAT ZNF250 ZNF408 ZNF564 ZNF774
Entrez ID		7593	23641
HPRD ID		01930	02322
Ensembl ID		ENSG00000099326	ENSG00000182195
Uniprot IDs		P28698	O95751
PDB IDs		2FI2
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Fibroblast Proliferation Cell Dedifferentiation Regulation Of Fibroblast Proliferation G1/S Transition Of Mitotic Cell Cycle Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Senescence Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Cell Size Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Hematopoietic Stem Cell Differentiation Negative Regulation Of Cell Aging Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Biosynthetic Process Dentate Gyrus Development Type B Pancreatic Cell Development Astrocyte Development Negative Regulation Of Gene Expression Type B Pancreatic Cell Differentiation Negative Regulation Of Cell Cycle Arrest Negative Regulation Of Biosynthetic Process Lateral Ventricle Development Enteroendocrine Cell Differentiation Cell Division Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cellular Senescence Response To Lead Ion Response To Hyperoxia Negative Regulation Of Cell Cycle Glandular Epithelial Cell Development Regulation Of Cell Proliferation Response To Testosterone Regulation Of Erythrocyte Differentiation	Gene Expression Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Apoptotic Process Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Programmed Cell Death Cell Death Death Negative Regulation Of Gene Expression Regulation Of Cellular Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Apoptotic Process Biosynthetic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Gene Expression Regulation Of Cell Death Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Signal Transduction Negative Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Signaling Negative Regulation Of Wnt Signaling Pathway Melanosome Organization Pigment Granule Organization
Tagcloud ?		base cdc37 chick clusters conforms consensus copies emphasize exons finger flanking gctat ggg glycosaminoglycans homeodomain hsp90 introns kilobases pair presumptive promotion reorganization repetitive s8 sizes sp1 stabilization striking tatgggga	abcc5 cabpr cbr3 clonogenic comprehensive differentially dock8 dsc2 esophageal extracted fabp5 global gpx2 hence know microarray ndn nme oligonucleotide radiation radioresistant radiosensitive radiosensitivities radiosensitivity radiotherapy rpa1 skp1a spot te
Tagcloud (Difference) ?		base cdc37 chick clusters conforms consensus copies emphasize exons finger flanking gctat ggg glycosaminoglycans homeodomain hsp90 introns kilobases pair presumptive promotion reorganization repetitive s8 sizes sp1 stabilization striking tatgggga	abcc5 cabpr cbr3 clonogenic comprehensive differentially dock8 dsc2 esophageal extracted fabp5 global gpx2 hence know microarray ndn nme oligonucleotide radiation radioresistant radiosensitive radiosensitivities radiosensitivity radiotherapy rpa1 skp1a spot te
Tagcloud (Intersection) ?