SF1 and ILF3

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		SF1	ILF3
Gene Name		splicing factor 1	interleukin enhancer binding factor 3, 90kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Ribosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Membrane Ribonucleoprotein Complex
	Molecular Function	Transcription Corepressor Activity RNA Binding Zinc Ion Binding Poly(A) RNA Binding	DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Spliceosomal Complex Assembly MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated Male Sex Determination Leydig Cell Differentiation Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Steroid Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription	Transcription, DNA-templated Protein Phosphorylation Negative Regulation Of Translation Negative Regulation Of Viral Genome Replication Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Defense Response To Virus
Pathways
Drugs
Diseases
GWAS		Urate levels ( 21768215)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		45 interactors: APBB1 ATXN1 BCAS2 BCL2 CIAO1 DDX17 EFTUD2 ESR1 EWSR1 FAM168A FUS GAS7 HNRNPF HNRNPH1 HNRNPH2 HNRNPK HNRNPUL1 IL7R ILF3 ITCH KRTAP26-1 MKRN3 NFKB1 PLSCR1 PNRC2 PRKG1 PRPF40A PSMA3 RBM10 RBM17 RBM4 RBM7 RBPMS SF3A1 SF3B4 TAF15 TCERG1 TRIM23 TRIM69 U2AF2 WBP4 WDR77 WDR83 WWP2 ZNF461	26 interactors: DHX9 EIF2AK2 ERG FUS GDF9 HNRNPH2 IL7R KRTAP4-12 LNX1 MAGEA11 MDFI NDRG1 PLSCR1 PRMT1 RBM5 RBPMS RNF113A SF1 SF3B4 SMN1 SNRPC TRIP6 XAB2 XPO5 ZNF346 ZNF830
Entrez ID		7536	3609
HPRD ID		03306	04420
Ensembl ID		ENSG00000168066	ENSG00000129351
Uniprot IDs		Q15637	Q12906
PDB IDs		1K1G 1OPI 2M09 2M0G 4FXW 4FXX	2L33 3P1X
Enriched GO Terms of Interacting Partners?		RNA Processing RNA Splicing MRNA Processing MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Metabolic Process Metabolic Process Transcription, DNA-templated Regulation Of RNA Splicing RNA Biosynthetic Process Cellular Process Positive Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Protein Ubiquitination Cellular Macromolecule Biosynthetic Process Response To Virus Positive Regulation Of Cellular Metabolic Process Protein Modification By Small Protein Conjugation Macromolecule Biosynthetic Process Defense Response To Virus Regulation Of MRNA Splicing, Via Spliceosome Protein Polyubiquitination Regulation Of Viral Genome Replication Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Process Positive Regulation Of Transcription, DNA-templated Regulation Of MRNA Processing Transcription From RNA Polymerase II Promoter Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Activation Apoptotic Process Response To Other Organism	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Gene Expression RNA Metabolic Process Spliceosomal Complex Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Regulation Of Gene Expression Regulation Of Female Gonad Development Ribonucleoprotein Complex Biogenesis Regulation Of Hematopoietic Progenitor Cell Differentiation Cellular Metabolic Process Regulation Of Protein Import Into Nucleus Spliceosomal SnRNP Assembly Regulation Of Nitrogen Compound Metabolic Process MRNA Splice Site Selection Negative Regulation Of Viral Genome Replication Regulation Of Protein Localization To Nucleus Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Evasion Or Tolerance By Virus Of Host Immune Response Negative Regulation Of Potassium Ion Export Regulation Of Nucleocytoplasmic Transport In Utero Embryonic Development Regulation Of RNA Metabolic Process Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Intracellular Protein Transport Regulation Of Heart Rate By Hormone Interleukin-7-mediated Signaling Pathway Regulation Of Hematopoietic Stem Cell Differentiation Oocyte Growth Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Cellular Response To Stress Cellular Macromolecular Complex Assembly Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Intestinal Epithelial Structure Maintenance Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Metabolic Process Regulation Of MRNA Processing Regulation Of Transcription Factor Import Into Nucleus Regulation Of Translational Initiation By EIF2 Alpha Phosphorylation
Tagcloud ?		aaggtcagaaat aromatase belong br clones coup decided differently dnase ear encode err footprinting hybrid mobility ovary p120e4f promoters s1 shorter silencer situated sk specimen superfamily tf1 variant ws3tf	acting analogues axis cll cytotoxicity dca dichloroacetate emphasize exhibits harboring hl indeed invariably knocking leukemic lymphocytic maver mec mediating merits options p21 p53mutated p53null p53wild proteomic purine sirnas underscored
Tagcloud (Difference) ?		aaggtcagaaat aromatase belong br clones coup decided differently dnase ear encode err footprinting hybrid mobility ovary p120e4f promoters s1 shorter silencer situated sk specimen superfamily tf1 variant ws3tf	acting analogues axis cll cytotoxicity dca dichloroacetate emphasize exhibits harboring hl indeed invariably knocking leukemic lymphocytic maver mec mediating merits options p21 p53mutated p53null p53wild proteomic purine sirnas underscored
Tagcloud (Intersection) ?