YWHAZ and MAP3K5

  • Number of citations of the paper that reports this interaction (PMID 10411906)
  • 70
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo, in vitro)

YWHAZ

MAP3K5

Gene Name tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta mitogen-activated protein kinase kinase kinase 5
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Attention deficit hyperactivity disorder and conduct disorder ( 18951430)
Protein-Protein Interactions 191 interactors: AANAT ABL1 ADAM22 ADRA2A ADRA2B ADRA2C AKAP13 AKT1 APP ARAF ARHGEF2 ATP5A1 ATXN1 BAD BCAR1 BCR BRAF BSPRY CBL CDC25A CDC25B CDC25C CDC5L CDK11B CDK16 CDK17 CDKN1B CENPJ CFL1 CGNL1 CLIC4 CRTC2 CSF2RB CSNK1A1 CSNK1D DFFA DISC1 EFNB3 EGFR EIF3A ENO1 EPB41L1 EPB41L2 EPB41L3 EXO1 FAM13B FAM53C FHOD1 FOXO1 FOXO3 FOXO4 GABARAPL2 GABBR1 GCH1 GP1BA GP1BB GP5 HDAC4 HDAC9 HIST1H3A HIVEP2 HMGN1 HSPA1A HSPA1B IGF1R IL9R ING1 INPP5A IRS1 IRS2 KCNK15 KCNK3 KCNK9 KIAA0232 KIAA0930 KIAA1377 KIF1C KIF5B KLC2 KLC4 KLF11 KRT18 KSR1 LARP1 LCP2 LIMK1 LRMP LYST MADD MAP2K5 MAP3K2 MAP3K3 MAP3K4 MAP3K5 MAPK8 MAPKAPK2 MAPT MARK2 MARK3 MARK4 MDM4 MEF2C MINK1 MLF1 MPHOSPH9 MSL2 MST1R MYH9 NEDD4L NFATC2 NFATC4 NR4A1 PAK1 PAK4 PARD3 PARD6A PARD6B PDC PFKFB2 PIAS1 PPP1CC PPP1R14A PRDX2 PRKCA PRKCD PRKCI PRKCZ PRKD1 PRLR PRMT5 PSMA5 PTPN13 PTPRO RAF1 RALGPS2 RAP1GAP2 RASAL3 REM1 RFWD2 RGS3 RIN1 RMDN3 RPRD1A RRAD SAMSN1 SH3GL1 SIK1 SIK3 SIMC1 SLC8A2 SNX24 SORBS2 SQSTM1 SSFA2 SSX2IP STK25 STK38 SYN2 SYNPO SYNPO2 TAB2 TBXA2R TERT TH TJP2 TLK2 TNFAIP3 TNS1 TP53 TPD52L1 TPH1 TRA2B TRIM21 TSC1 TSC2 TUBB UBC UBE3A UCHL5 UCP2 UCP3 VCP VIM WEE1 WNK1 WNK2 WWTR1 XRCC6 YWHAE ZAK ZNF839 50 interactors: AKT1 AKT2 ARRB1 ARRB2 CDC25A CDKN1A CREBBP DAB2IP DAXX DMD DUSP19 EIF2AK2 EP300 ERN1 GADD45B GEMIN5 GLRX GSTM1 HSPA1A IGF1R JAK2 MAP2K4 MAP2K6 MAP2K7 MAP3K2 MAP3K3 MAP3K6 MAP3K7 MAPK8IP3 MBP NEDD4 NEDD4L PDCD6 PPP3R1 PPP5C PTPN11 QARS RAF1 SFN TNNT2 TPD52L1 TRAF2 TRAF5 TRAF6 TXN USP9X YWHAE YWHAH YWHAQ YWHAZ
Entrez ID 7534 4217
HPRD ID 03183 03904
Ensembl ID ENSG00000164924 ENSG00000197442
Uniprot IDs D0PNI1 P63104 Q99683
PDB IDs 1IB1 1QJA 1QJB 2C1J 2C1N 2O02 2WH0 3CU8 3NKX 3RDH 4BG6 4FJ3 4HKC 4IHL 2CLQ 3VW6 4BF2 4BHN 4BIB 4BIC 4BID 4BIE
Enriched GO Terms of Interacting Partners?
Tagcloud ?
actb  arfgap2  arl1  bestkeeper  bmi1  casc3  cynomolgus  ddx3x  gapdh  genorm  lists  monkey  morf4  mrfap1  normalization  normfinder  ormdl1  prerequisite  reference  ribosylation  rps19  rsl24d1  sar1a  traditionally  transcriptome  usp22  vitally  zc3h11a  zranb2 
199a2  angptl2  awry  chondrosarcoma  cmet  discovering  dnm3  evenly  fibrosarcoma  flt1  flt4  foxl1  genetics  gli1  hif1alpha  hmga2  kdr  liposarcoma  mdk  med12  muc4  mycn  osteocytes  pcsk1  relentless  sarcoma  tek  tie1  yeats4 
Tagcloud (Difference) ?
actb  arfgap2  arl1  bestkeeper  bmi1  casc3  cynomolgus  ddx3x  gapdh  genorm  lists  monkey  morf4  mrfap1  normalization  normfinder  ormdl1  prerequisite  reference  ribosylation  rps19  rsl24d1  sar1a  traditionally  transcriptome  usp22  vitally  zc3h11a  zranb2 
199a2  angptl2  awry  chondrosarcoma  cmet  discovering  dnm3  evenly  fibrosarcoma  flt1  flt4  foxl1  genetics  gli1  hif1alpha  hmga2  kdr  liposarcoma  mdk  med12  muc4  mycn  osteocytes  pcsk1  relentless  sarcoma  tek  tie1  yeats4 
Tagcloud (Intersection) ?