WARS and DCAF13

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		WARS	DCAF13
Gene Name		tryptophanyl-tRNA synthetase	DDB1 and CUL4 associated factor 13
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome	Nucleolus Small-subunit Processome Cul4-RING E3 Ubiquitin Ligase Complex
	Molecular Function	Tryptophan-tRNA Ligase Activity Protein Binding ATP Binding	Poly(A) RNA Binding
	Biological Process	Angiogenesis Translation TRNA Aminoacylation For Protein Translation Tryptophanyl-tRNA Aminoacylation Negative Regulation Of Cell Proliferation Gene Expression Regulation Of Angiogenesis	Maturation Of SSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Protein Ubiquitination
Pathways		Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs		L-Tryptophan Tryptophanyl-5\'amp L-Tryptophanamide
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APP CDK2AP2 DCAF13 DNMT3B EEF1A1 LIG4 MDH2 TERF1	2 interactors: TK1 WARS
Entrez ID		7453	25879
HPRD ID		01845	08528
Ensembl ID		ENSG00000140105	ENSG00000164934
Uniprot IDs		P23381	Q9NV06
PDB IDs		1O5T 1R6T 1R6U 1ULH 2AKE 2AZX 2DR2 2QUH 2QUI 2QUJ 2QUK
Enriched GO Terms of Interacting Partners?		Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Neuron Apoptotic Process Neuron Death Response To Radiation Negative Regulation Of Chromosome Organization DNA Ligation Involved In DNA Recombination Positive Regulation Of Mitotic Cell Cycle Synaptic Growth At Neuromuscular Junction Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Response To Ionizing Radiation Regulation Of Neurogenesis Collateral Sprouting In Absence Of Injury Telomeric Loop Formation Age-dependent Telomere Shortening S-adenosylmethioninamine Metabolic Process Telomere Maintenance Via Telomere Shortening DNA Methylation On Cytosine Within A CG Sequence Negative Regulation Of Cellular Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Cell Development Regulation Of Chromosome Organization Negative Regulation Of Protein Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis C-5 Methylation Of Cytosine Lagging Strand Elongation Pro-B Cell Differentiation Negative Regulation Of Telomere Maintenance Via Telomerase S-adenosylhomocysteine Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Axon Choice Point Recognition Regulation Of Cell Cycle Phase Transition Methylation-dependent Chromatin Silencing Establishment Of Integrated Proviral Latency Chromosome Organization Neuron Remodeling Immunoglobulin V(D)J Recombination Replicative Cell Aging Establishment Of Viral Latency Cellular Metabolic Process DNA Metabolic Process DNA Replication Positive Regulation Of Cell Cycle Response To Abiotic Stimulus T Cell Receptor V(D)J Recombination	Fetal Process Involved In Parturition Tryptophanyl-tRNA Aminoacylation Skeletal Muscle Cell Proliferation Thymidine Metabolic Process Response To Cortisol Deoxyribonucleoside Monophosphate Biosynthetic Process Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Parturition Response To Copper Ion Pyrimidine Nucleobase Metabolic Process Pyrimidine Nucleoside Biosynthetic Process Protein Homotetramerization Pyrimidine Nucleoside Metabolic Process TRNA Aminoacylation For Protein Translation TRNA Aminoacylation Nucleoside Monophosphate Biosynthetic Process Protein Tetramerization DNA Biosynthetic Process Small Molecule Metabolic Process Digestive Tract Development Digestive System Development Liver Development Response To Glucocorticoid Response To Corticosteroid Response To Toxic Substance
Tagcloud ?		aspect attenuation axonal bd binswanger cognition computerized concerned conduction cz dementia deterioration disrupted disturbing handedness hbo hyperbaric latency measurement neurophysiological neuropsychological oxygenation rc reflects scanned subcortical tendency wais wmla
Tagcloud (Difference) ?		aspect attenuation axonal bd binswanger cognition computerized concerned conduction cz dementia deterioration disrupted disturbing handedness hbo hyperbaric latency measurement neurophysiological neuropsychological oxygenation rc reflects scanned subcortical tendency wais wmla
Tagcloud (Intersection) ?