MPPED2 and VAC14

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MPPED2	VAC14
Gene Name		metallophosphoesterase domain containing 2	Vac14 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Golgi Membrane Endoplasmic Reticulum Endosome Membrane Early Endosome Membrane Late Endosome Membrane PAS Complex
	Molecular Function	Hydrolase Activity Metal Ion Binding	Receptor Activity Protein Binding
	Biological Process	Nervous System Development Metabolic Process	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Signal Transduction Viral Process Regulation Of Lipid Kinase Activity Small Molecule Metabolic Process
Pathways			Phospholipid metabolism Synthesis of PIPs at the late endosome membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Synthesis of PIPs at the late endosome membrane Metabolism Synthesis of PIPs at the Golgi membrane Metabolism of lipids and lipoproteins Synthesis of PIPs at the early endosome membrane PI Metabolism Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS		Chronic kidney disease ( 22479191) Dental caries ( 21940522) Renal function-related traits (eGRFcrea) ( 22797727) Renal function-related traits (sCR) ( 22797727)
Protein-Protein Interactions		6 interactors: CAGE1 FAM72A NOTCH3 RXRG TRIP13 VAC14	47 interactors: ACSS1 APP ASB13 BHLHE40 C11orf54 C4orf33 CASP1 CCBL1 CCDC103 CD209 CDRT4 CNTN2 COL8A1 DDAH2 FIG4 FNDC3B JMJD7 KRTAP19-5 KRTAP19-7 LINC00518 LPAL2 MGAT5B MPPED2 MTMR9 MVP NGB NOS1 PCMTD2 PDE4DIP PELI1 PHF1 PHYKPL PIKFYVE PPP2CA PRADC1 PRR13 PRR20A RBFOX2 RHOXF2 SIGLEC5 SMUG1 SNF8 SPRYD7 TCEANC TP53BP1 WDYHV1 ZNF34
Entrez ID		744	55697
HPRD ID		02947	07660
Ensembl ID		ENSG00000066382	ENSG00000103043
Uniprot IDs		Q15777	Q08AM6 Q9NTB8
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Glomerular Capillary Formation Biosynthetic Process Female Meiosis I Glomerulus Morphogenesis Transcription, DNA-templated Glomerulus Vasculature Development Notch Receptor Processing RNA Biosynthetic Process Synaptonemal Complex Assembly Oocyte Maturation Synaptonemal Complex Organization Retinoic Acid Receptor Signaling Pathway Male Meiosis I Cellular Response To Stimulus Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus Female Meiotic Division Reciprocal Meiotic Recombination Oocyte Development Cardiovascular System Development Oocyte Differentiation Regulation Of Myelination RNA Metabolic Process Synapsis Regulation Of Lipid Kinase Activity Homologous Chromosome Segregation Positive Regulation Of Smooth Muscle Cell Proliferation Regulation Of Metabolic Process Male Meiosis Glomerulus Development Cell Differentiation Gene Expression Protein Homotetramerization Cellular Macromolecule Biosynthetic Process Neuron Differentiation Oogenesis Macromolecule Biosynthetic Process Neuron Fate Commitment Meiotic Chromosome Segregation	Arginine Catabolic Process Nitric Oxide Biosynthetic Process Nitric Oxide Mediated Signal Transduction Arginine Metabolic Process Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Phosphatidylinositol-3-phosphate Biosynthetic Process Nitric Oxide Metabolic Process Cellular Amino Acid Catabolic Process Cell Recognition Regulation Of Protein Autophosphorylation Reactive Nitrogen Species Metabolic Process Neuron Maturation Myelin Assembly Second-messenger-mediated Signaling Myelination Neuron Recognition Axon Ensheathment
Tagcloud ?			abundance alleles biosynthesis charcot conditional dependence discovery endolysosomal fab1 fig4 highlights insight knockouts learned macromolecular manipulating marie neurological p2 p2in pi pikfyve spontaneous summarizes tooth turnover utility varon yunis
Tagcloud (Difference) ?			abundance alleles biosynthesis charcot conditional dependence discovery endolysosomal fab1 fig4 highlights insight knockouts learned macromolecular manipulating marie neurological p2 p2in pi pikfyve spontaneous summarizes tooth turnover utility varon yunis
Tagcloud (Intersection) ?