VDAC1 and DYNLT3

Number of citations of the paper that reports this interaction (PMID 12009301)
23

Data Source:
HPRD (in vitro, two hybrid)

		VDAC1	DYNLT3
Gene Name		voltage-dependent anion channel 1	dynein, light chain, Tctex-type 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Outer Membrane Mitochondrial Inner Membrane Plasma Membrane Membrane Mitochondrial Nucleoid Pore Complex Extracellular Vesicular Exosome	Kinetochore Condensed Chromosome Kinetochore Nucleus Cytoplasmic Dynein Complex Microtubule
	Molecular Function	Protein Binding Voltage-gated Anion Channel Activity Porin Activity Protein Kinase Binding	Motor Activity Identical Protein Binding
	Biological Process	Behavioral Fear Response Anion Transport Apoptotic Process Neuron-neuron Synaptic Transmission Learning Viral Process Epithelial Cell Differentiation Regulation Of Anion Transport Transmembrane Transport	Transport Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Metabolic Process Cell Division
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS
Protein-Protein Interactions		20 interactors: ADRB2 BAK1 BAX BCL2L1 BCL2L11 CKMT1A CKMT1B CSNK2B DYNLT1 DYNLT3 GSN HK1 KLHL40 MCL1 PPIF PRKCE RAF1 SUMO4 TOMM20 TUBA4A	7 interactors: CD5 DYNC1I1 DYNC1I2 NIF3L1 PVR TESC VDAC1
Entrez ID		7416	6990
HPRD ID		05137	02249
Ensembl ID		ENSG00000213585	ENSG00000165169
Uniprot IDs		B3KTS5 P21796	P51808 Q6ICS3
PDB IDs		2JK4 2K4T
Enriched GO Terms of Interacting Partners?		Apoptotic Mitochondrial Changes Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Extrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Mitochondrial Membrane Organization Mitochondrial Transport Positive Regulation Of Release Of Cytochrome C From Mitochondria Thymocyte Apoptotic Process B Cell Apoptotic Process Post-embryonic Organ Morphogenesis Positive Regulation Of Apoptotic Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Mitochondrion Organization Mitochondrion Organization Positive Regulation Of Signal Transduction Apoptotic Process Programmed Cell Death Cell Death Death Positive Regulation Of Mitochondrion Organization Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Intrinsic Apoptotic Signaling Pathway T Cell Apoptotic Process Apoptotic Signaling Pathway Transport Regulation Of Organelle Organization Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Organelle Organization B Cell Negative Selection Apoptotic Process Involved In Morphogenesis Organelle Organization Apoptotic Process Involved In Development Establishment Of Localization In Cell Intracellular Transport Release Of Cytochrome C From Mitochondria Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Mitochondrial Membrane Permeability Involved In Programmed Necrotic Cell Death Apoptotic Process Involved In Embryonic Digit Morphogenesis Post-embryonic Camera-type Eye Morphogenesis Positive Regulation Of Intracellular Signal Transduction Regulation Of Mitochondrial Membrane Potential Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Signal Transduction B Cell Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Developmental Programmed Cell Death Regulation Of Intracellular Signal Transduction Positive Regulation Of Apoptotic Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Viral Process Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Susceptibility To T Cell Mediated Cytotoxicity 7,8-dihydroneopterin 3'-triphosphate Biosynthetic Process Dihydrobiopterin Metabolic Process Positive Regulation Of Sodium:proton Antiporter Activity Susceptibility To Natural Killer Cell Mediated Cytotoxicity Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Immune System Process Immune System Process Antigen Processing And Presentation Of Peptide Antigen Positive Regulation Of Immune Response To Tumor Cell Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Megakaryocyte Differentiation Antigen Processing And Presentation Microtubule-based Movement Regulation Of Proton Transport Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Transmembrane Transport Regulation Of Immune System Process Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Megakaryocyte Differentiation Transport Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Ion Transmembrane Transport Megakaryocyte Differentiation Regulation Of Natural Killer Cell Mediated Cytotoxicity Movement Of Cell Or Subcellular Component Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Sodium Ion Transmembrane Transporter Activity
Tagcloud ?		000xg calreticulin cd81 centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vesicle	associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynll1 dynll2 dynlrb1 dynlrb2 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Difference) ?		000xg calreticulin cd81 centrifugation cleared contaminating devoid dulbecco eagle exosomal exosome exosomes fill fl3 hek293 impacted microsomes nanoparticle nta overnight pelleted phenol purity sedimentation speeds syntenin tsg101 ultracentrifugation vesicle	associates bicd2 bona chains cilia ciliopathies ciliopathy define dynactin dynein dynll1 dynll2 dynlrb1 dynlrb2 encoded fide ift intraflagellar lc8 lis1 nudcd3 pafah1b1 retrograde roadblock tctex tctex1d2 wdr34 wdr60
Tagcloud (Intersection) ?