UGCG and RTN1

Number of citations of the paper that reports this interaction (PMID 12873973)
6

Data Source:
HPRD (in vivo, two hybrid)

		UGCG	RTN1
Gene Name		UDP-glucose ceramide glucosyltransferase	reticulon 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Membrane Integral Component Of Membrane	Endoplasmic Reticulum Membrane Integral Component Of Endoplasmic Reticulum Membrane
	Molecular Function	Ceramide Glucosyltransferase Activity	Protein Binding
	Biological Process	Sphingolipid Metabolic Process Glucosylceramide Biosynthetic Process Glycosphingolipid Metabolic Process Glycosphingolipid Biosynthetic Process Epidermis Development Small Molecule Metabolic Process	Neuron Differentiation
Pathways		Sphingolipid metabolism Metabolism of lipids and lipoproteins Glycosphingolipid metabolism
Drugs		Miglustat
Diseases
GWAS
Protein-Protein Interactions		3 interactors: APP RTN1 RTN3	7 interactors: BCL2L1 FAM160A2 HDAC8 PLEKHF2 SDCBP SPAST UGCG
Entrez ID		7357	6252
HPRD ID		04190	02921
Ensembl ID			ENSG00000139970
Uniprot IDs		Q16739	A8K3B9 Q16799
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Endoplasmic Reticulum Tubular Network Organization Neuron Remodeling	Regulation Of Organelle Organization Apoptotic Process In Bone Marrow Glucosylceramide Biosynthetic Process Cytokinesis Intracellular Transport Organelle Organization Cytokinesis, Completion Of Separation Mitotic Cell Cycle Positive Regulation Of Extracellular Vesicular Exosome Assembly Suppression By Virus Of Host Apoptotic Process Regulation Of Cohesin Localization To Chromatin Regulation Of Cellular Component Organization Positive Regulation Of Microtubule Depolymerization Glucosylceramide Metabolic Process Establishment Of Localization In Cell Cell Part Morphogenesis Regulation Of Extracellular Vesicular Exosome Assembly Response To Cycloheximide Cellular Process Regulating Host Cell Cycle In Response To Virus Mitotic Cytokinetic Process Protein Hexamerization Negative Regulation Of Execution Phase Of Apoptosis Regulation Of Cellular Localization Cell Cycle Process Cellular Localization Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Substrate-dependent Cell Migration, Cell Extension Cellular Response To Virus Microtubule Severing Modulation By Virus Of Host Process Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Anoikis Cellular Response To Gamma Radiation Hepatocyte Apoptotic Process Regulation Of Sister Chromatid Cohesion Cell Cycle Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Anoikis Cell Separation After Cytokinesis Positive Regulation Of Protein Depolymerization Transport Positive Regulation Of Organelle Organization Protein Transport Early Endosome To Late Endosome Transport Negative Regulation Of Protein Localization To Plasma Membrane Cell Division Vesicle-mediated Transport Mitochondrion Morphogenesis Modulation By Virus Of Host Morphology Or Physiology
Tagcloud ?			astrocyte clues constitute exert explore fi fl galactosidase glutathione homo immuno interacting library manf media mesencephalic neurotrophic proapoptotic pull regular reticular reticulons rtns sapiens screen speci transferase uorescence verified
Tagcloud (Difference) ?			astrocyte clues constitute exert explore fi fl galactosidase glutathione homo immuno interacting library manf media mesencephalic neurotrophic proapoptotic pull regular reticular reticulons rtns sapiens screen speci transferase uorescence verified
Tagcloud (Intersection) ?