UBE2I and SETD8

  • Number of citations of the paper that reports this interaction (PMID 21829513)
  • 4
  • Data Source:
  • BioGRID (pull down, affinity chromatography technology, pull down, enzymatic study)

UBE2I

SETD8

Gene Name ubiquitin-conjugating enzyme E2I SET domain containing (lysine methyltransferase) 8
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 258 interactors: ADAR ANXA1 APEX1 AR ARNT ARNTL ATF2 ATF7IP ATXN1 BCAM BEND5 BIRC3 BIRC7 BLM BLMH BMI1 C18orf25 CARM1 CASP2 CASP8AP2 CBLC CBS CBX4 CDC37 CDCA8 CEBPD CEBPE CFTR CHD3 CHFR CHMP1A CHMP4B CHUK CLDN2 CLK2 CORO2A CREB1 CREBBP CREM CSNK2B CTBP2 DACH1 DAXX DES DHX9 DNM1 DNMT3A DNMT3B DRG1 DTX3L DZIP3 EDARADD EDF1 EGR2 ELK1 EP300 ESR1 ETS1 ETV6 EXOSC9 FAS FHIT FHL3 FLI1 FMR1 FOS FOXM1 GCM1 GLUL GMCL1P1 GMEB1 GMEB2 GOLGA2 GOLGB1 GRIP1 HABP4 HDAC1 HDAC4 HDAC5 HDAC7 HGS HIC1 HIPK1 HIPK2 HIPK3 HIST1H4A HIST4H4 HMGN2 HNF4A HNRNPC HNRNPD HNRNPK HNRNPLL HSF1 HSF2 HSF2BP IKZF1 IKZF3 IPO13 JUN KCNK1 KCTD1 KLHL12 KRT19 LMNA LMO2 LNX2 MAP3K1 MAPK1IP1L MARCH5 MDM2 MED7 MGRN1 MITF MKL1 MKRN3 MTA1 MYB NCOR2 NIN NR1D2 NR1H2 NR3C1 NR3C2 NR5A2 NUDCD3 PARK7 PARP1 PDLIM7 PDZK1 PELI1 PEX10 PHC1 PIAS1 PIAS2 PIAS3 PIAS4 PLAGL1 PML PPARA PPARGC1A PPM1J PRKAA2 PRPF40A PSMC3 PTEN PUF60 RAD18 RAD51 RAD52 RAD54B RAD54L2 RANBP2 RANGAP1 RB1 RBBP5 RBBP6 RC3H2 RCBTB2 RFPL3 RIPK2 RNF10 RNF111 RNF115 RNF128 RNF133 RNF144B RNF185 RNF4 RNF40 RORB RPS6KA6 SAE1 SALL1 SATB1 SCNN1A SETBP1 SETD8 SETDB1 SETX SIAH1 SIAH2 SIRT1 SKIL SLC2A1 SLC2A4 SMAD4 SNIP1 SOCS6 SOX10 SOX4 SP100 SP3 SPECC1L SREBF1 SREBF2 SRF STAT1 STRA13 SUMO1 SUMO1P1 SUMO2 SUMO3 SUZ12 TAB2 TAF1 TAF10 TAF12 TAF5 TBP TCF3 TCF7L2 TDG TDP2 TFAP2A TFAP2B TFAP2C TNFRSF1A TOP1 TOPORS TP53 TP63 TP73 TRAF3 TRAF4 TRAF6 TRIM21 TRIM23 TRIM27 TRIM28 TRIM29 TRIM38 TRIM41 TRIM54 TRIM63 TRIM72 TRPS1 UBA2 UBE2K UBXN1 UCHL1 UNC119 USP25 WHSC1L1 WT1 XBP1 XIAP ZBED1 ZBTB16 ZBTB26 ZBTB8A ZCCHC7 ZEB2 ZMYM2 ZNF106 ZNF451 ZNF646 ZNRD1 9 interactors: DTL E2F2 FAM9A HIST4H4 LEF1 PCNA TP53 TWIST1 UBE2I
Entrez ID 7329 387893
HPRD ID 09045 06254
Ensembl ID ENSG00000103275 ENSG00000183955
Uniprot IDs A8K503 B0QYN7 P63279 E3VVS3 Q9NQR1
PDB IDs 1A3S 1KPS 1Z5Q 1Z5S 2GRN 2GRO 2GRP 2GRQ 2GRR 2O25 2PE6 2PX9 2XWU 3A4S 3UIN 3UIO 3UIP 1ZKK 2BQZ 3F9W 3F9X 3F9Y 3F9Z 4IJ8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
array  c9orf72  carriers  conjugating  consisting  deregulation  discovery  displays  encode  except  expansion  frontotemporal  ftd  generalized  grn  matched  preliminary  proteasomal  proteasome  sabiosciences  sporadic  statistically  ube2e1  ube2n  ube2q1  ube2z  ubiquitin  ubiquitination 
5a  battery  biophysical  catalyzes  competitive  comprehensive  discovery  extensively  h4  h4k20  interesting  kmt5a  lysine  methyltransferase  methyltransferases  monomethylates  monomethylation  pcna  potencies  proliferating  pursued  quinazoline  sar  scaffold  set7  set8  substituents  trends  unc0379 
Tagcloud (Difference) ?
array  c9orf72  carriers  conjugating  consisting  deregulation  displays  encode  except  expansion  frontotemporal  ftd  generalized  grn  matched  preliminary  proteasomal  proteasome  sabiosciences  sporadic  statistically  ube2e1  ube2n  ube2q1  ube2z  ubiquitin  ubiquitination 
5a  battery  biophysical  catalyzes  competitive  comprehensive  extensively  h4  h4k20  interesting  kmt5a  lysine  methyltransferase  methyltransferases  monomethylates  monomethylation  pcna  potencies  proliferating  pursued  quinazoline  sar  scaffold  set7  set8  substituents  trends  unc0379 
Tagcloud (Intersection) ?
discovery