TSC2 and AKT2

  • Number of citations of the paper that reports this interaction (PMID 12167664)
  • 80
  • Data Source:
  • HPRD (in vivo)

TSC2

AKT2

Gene Name tuberous sclerosis 2 v-akt murine thymoma viral oncogene homolog 2
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 40 interactors: AKT1 AKT2 AKT3 CALM1 CCND1 CDKN1B ESR1 FBXL6 FBXW5 GRB2 GSK3B LNX1 MAPK1 MAPK3 MAPKAPK2 MDFI NEK1 PAM PIN1 PPP2CA PRKAA1 PTK2 RAB5A RABEP1 RHEB RPS6KA1 SFN SMAD2 SMAD3 SPERT TBC1D7 TK1 TSC1 UBE3A YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ 38 interactors: ABCG8 AKT1 AKT1S1 APOA1 APOB APP APPL1 CCL14 CHUK CLIP3 ESR1 FOXO4 FSHR GSK3B HIST1H3A HSP90AA1 MAP3K5 MTCP1 NAMPT PDPK1 PLEKHO1 PNPLA3 POFUT1 POLR1B PRKDC RAB3D SH3RF1 SLC2A4 SNX27 SORBS2 SPRR2A STEAP4 TCL1A TCL1B TMED2 TRIB3 TSC2 XIAP
Entrez ID 7249 208
HPRD ID 01850 01262
Ensembl ID ENSG00000103197 ENSG00000105221
Uniprot IDs P49815 B4DG79 P31751
PDB IDs 1GZK 1GZN 1GZO 1MRV 1MRY 1O6K 1O6L 1P6S 2JDO 2JDR 2UW9 2X39 2XH5 3D0E 3E87 3E88 3E8D
Enriched GO Terms of Interacting Partners?
Tagcloud ?
c3  calpactine  carcinogenesis  clones  complement  designated  dominantly  eker  erc  example  excellent  fos  fra  gap3  germline  gives  gtpase  hereditary  homologous  homologue  inherited  insertion  mendelian  predisposition  representational  rise  subtracted  tuberine  tuberous 
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
Tagcloud (Difference) ?
c3  calpactine  carcinogenesis  clones  complement  designated  dominantly  eker  erc  example  excellent  fos  fra  gap3  germline  gives  gtpase  hereditary  homologous  homologue  inherited  insertion  mendelian  predisposition  representational  rise  subtracted  tuberine  tuberous 
12q  12q21  14q31  15q25  16q23  18p  19q13  20p12  20pq  20q12  21q21  3p14  4pq  5p14  5q14  6p12  7p12  8q23  cardia  cdkn2  fist  gej  mlvi2  mts1  nrasl3  parentheses  ptpn1  rca1  xpq  xq25 
Tagcloud (Intersection) ?