TNNT1 and PNMA1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		TNNT1	PNMA1
Gene Name		troponin T type 1 (skeletal, slow)	paraneoplastic Ma antigen 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Troponin Complex	Nucleolus Cytoplasm Focal Adhesion
	Molecular Function	Tropomyosin Binding Troponin T Binding	Protein Binding
	Biological Process	Skeletal Muscle Contraction Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Negative Regulation Of Muscle Contraction	Inflammatory Response To Antigenic Stimulus Positive Regulation Of Apoptotic Process
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		61 interactors: ARMC8 BLOC1S2 BMPR1B C2orf44 CCDC136 CCDC85B CHD3 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HMP19 HSP90AB1 IMMT KAT5 KRT40 LARP1 LDOC1 MARS MORF4L1 NACAD NAGK NFE2L2 NINL OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TPM1 TPM3 TRA2A TRIM63 UBE2D1 VIM ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768	114 interactors: ANKRD36BP1 APTX ARID5A ASMTL ATP5O ATXN7 BEX2 BYSL C14orf105 C21orf58 C5orf30 C8orf33 CARHSP1 CCDC146 CCDC33 CCNG1 CCP110 CDK18 CFAP53 CHIC2 CHMP2B CNNM3 COX5B DCTN4 EHHADH ENKD1 FAM107A FAM110A FBF1 FBXL18 FEM1C FMNL2 GEM GPANK1 GPR25 GTPBP10 HDAC4 HOXB9 INO80B KANSL1 KAT2B LENG1 LIN37 MAB21L2 MARK4 MCM7 MED8 METTL17 MRPL10 MRPL11 MRPL23 MSI1 NPBWR2 NUDT16L1 PARD3 PARD6B PIN1 PIN4 PNMA5 PNMA6A POLDIP3 POLL POLM PRKCG PRKCI PRPF31 PSMA1 RAPGEF3 RBM41 RPP25L RSPH9 RSRC2 RTP5 RUSC1 SCAND1 SCNM1 SDCBP SEMA4C SH2D4A SHISA3 SLC25A48 SLIRP SMIM3 SNRPB SNRPB2 SPATC1L SPG7 STAMBPL1 SUV39H2 TCEANC TEAD4 TMSB4X TNNI1 TNNT1 TRIM42 TRPV6 TSPYL4 TTC9C TXNDC9 UBQLN1 UBQLN4 URB1-AS1 USP2 VAV2 VBP1 WDR25 WDYHV1 WT1-AS ZC2HC1C ZCCHC12 ZFYVE26 ZG16B ZNF564 ZNF581
Entrez ID		7138	9240
HPRD ID		01841	04926
Ensembl ID		ENSG00000105048	ENSG00000176903
Uniprot IDs		P13805	Q8ND90
PDB IDs
Enriched GO Terms of Interacting Partners?		Muscle Filament Sliding Actin-myosin Filament Sliding Actin-mediated Cell Contraction Actin Filament-based Movement Muscle System Process Regulation Of Metabolic Process Muscle Contraction Regulation Of Gene Expression Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Muscle Contraction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Ventricular Cardiac Muscle Tissue Morphogenesis Movement Of Cell Or Subcellular Component Ventricular Cardiac Muscle Tissue Development Regulation Of Cellular Process Cardiac Muscle Tissue Morphogenesis Signal Transduction Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Cellular Response To Organic Substance Muscle Tissue Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions Regulation Of RNA Metabolic Process Muscle Organ Morphogenesis Cardiac Ventricle Morphogenesis Cellular Macromolecule Biosynthetic Process BMP Signaling Pathway Positive Regulation Of Gene Expression Macromolecule Biosynthetic Process Signaling Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Striated Muscle Contraction Positive Regulation Of Cellular Biosynthetic Process Cell Communication Cellular Response To Transforming Growth Factor Beta Stimulus RNA Metabolic Process RNA Biosynthetic Process Response To Transforming Growth Factor Beta Cardiac Muscle Tissue Development Primary MiRNA Processing Cellular Response To Stimulus Regulation Of Cellular Component Organization Positive Regulation Of Apoptotic Signaling Pathway Response To Stimulus	Cell Cycle Apical Junction Assembly Organelle Organization Histone H3-K9 Modification
Tagcloud ?		apoc2 atp1a3 bckdha cgb cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb pepd prkcg psg1 pw39	adenocarcinoma apoptotic autoimmune bcl besides closely commonly decreases ductal erk expanding find mapk member neurological pancreatic paraneoplastic pdac pi3k pns pro promotes represent reveal suppression testis viability widely
Tagcloud (Difference) ?		apoc2 atp1a3 bckdha cgb cgm2 cyp2a d19s112 d19s116 d19s117 d19s118 d19s119 d19s19 d19s2 d19s37 d19s50 d19s51 d19s54 d19s55 d19s6 d19s62 d19s63 d19s7 d19s8 d19s9 manb pepd prkcg psg1 pw39	adenocarcinoma apoptotic autoimmune bcl besides closely commonly decreases ductal erk expanding find mapk member neurological pancreatic paraneoplastic pdac pi3k pns pro promotes represent reveal suppression testis viability widely
Tagcloud (Intersection) ?