DYNLT1 and SVIL

Number of citations of the paper that reports this interaction (PMID 16880273)
20

Data Source:
BioGRID (pull down)

		DYNLT1	SVIL
Gene Name		dynein, light chain, Tctex-type 1	supervillin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Spindle Cytoplasmic Dynein Complex Microtubule	Podosome Nucleus Cytoplasm Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Costamere Invadopodium
	Molecular Function	Motor Activity Protein Binding Identical Protein Binding	Protein Binding Actin Filament Binding
	Biological Process	Establishment Of Mitotic Spindle Orientation Mitotic Nuclear Division Metabolic Process Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Intracellular Transport Of Viral Protein In Host Cell Regulation Of Rac GTPase Activity Viral Entry Into Host Cell Neuron Projection Morphogenesis Negative Regulation Of Neurogenesis Cell Division Regulation Of Cytoskeleton Organization Microtubule-dependent Intracellular Transport Of Viral Material Towards Nucleus	Cytoskeleton Organization Skeletal Muscle Tissue Development Positive Regulation Of Cytokinesis
Pathways
Drugs
Diseases
GWAS			Normalized brain volume ( 19010793)
Protein-Protein Interactions		16 interactors: APP BAG3 BMPR2 DOC2A DOC2B DVL1 DVL2 DYNC1I1 HSPB9 PVR RAD21 SVIL TROAP TUBA3C TXN VDAC1	37 interactors: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF14 KIF22 KIFC3 KMT2A KRT18 LIMA1 LMNA LMNB2 LUC7L2 MIF4GD MKL2 MPHOSPH9 NME2 NR3C1 ODF2 P2RX7 PAN3 PCNXL3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG
Entrez ID		6993	6840
HPRD ID		15987	04992
Ensembl ID		ENSG00000146425	ENSG00000197321
Uniprot IDs		P63172	O95425 Q569J5
PDB IDs			2K6M 2K6N
Enriched GO Terms of Interacting Partners?		Convergent Extension Involved In Neural Plate Elongation Collateral Sprouting Convergent Extension Involved In Organogenesis Neural Plate Morphogenesis Planar Cell Polarity Pathway Involved In Neural Tube Closure Regulation Of Establishment Of Planar Polarity Involved In Neural Tube Closure Neurotransmitter Secretion Convergent Extension Neural Plate Development Wnt Signaling Pathway, Planar Cell Polarity Pathway Regulation Of Neurotransmitter Levels Cochlea Morphogenesis Neurotransmitter Transport Cell-cell Signaling Non-canonical Wnt Signaling Pathway Secretion By Cell Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cellular Localization Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Cochlea Development Neuromuscular Junction Development Regulation Of Binding Regulation Of Calcium Ion-dependent Exocytosis Secretion Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Protein Metabolic Process Morphogenesis Of An Epithelial Sheet Regulation Of Phosphorylation Regulation Of Protein Kinase Activity Microtubule-based Process Regulation Of Kinase Activity Regulation Of Lung Blood Pressure Synaptic Growth At Neuromuscular Junction Negative Regulation Of Chondrocyte Proliferation Susceptibility To T Cell Mediated Cytotoxicity Developmental Cell Growth Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component Canonical Wnt Signaling Pathway Regulation Of Cellular Amino Acid Metabolic Process Nervous System Development Inner Ear Morphogenesis Negative Regulation Of Vasoconstriction Collateral Sprouting In Absence Of Injury Regulation Of Embryonic Development Apoptotic Process Signaling Positive Regulation Of Canonical Wnt Signaling Pathway Ear Morphogenesis	Organelle Organization Regulation Of Cellular Component Organization Mitotic Cell Cycle Process Regulation Of Organelle Organization Mitotic Cell Cycle Cell Cycle Process Cell Cycle Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Mitotic Nuclear Division Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Component Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Complex Assembly Positive Regulation Of Transcription, DNA-templated Anatomical Structure Development Nitrogen Compound Metabolic Process Regulation Of Signal Transduction Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Metabolic Process Multicellular Organismal Development Positive Regulation Of Gene Expression Establishment Of Organelle Localization Apoptotic Process Transcription, DNA-templated Programmed Cell Death Regulation Of Signaling Microtubule-based Process Steroid Hormone Mediated Signaling Pathway Developmental Process Cell Death Death Establishment Of Localization In Cell RNA Biosynthetic Process Metaphase Plate Congression Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Positive Regulation Of Organelle Organization Transcription From RNA Polymerase II Promoter Response To Organic Substance G2/M Transition Of Mitotic Cell Cycle Organelle Localization Heterocycle Metabolic Process Establishment Of Protein Localization Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process
Tagcloud ?		1inq53a 250viqd 52gqvd adapter attempt capsid defective dynein hiv immunodeficiency integrase interaction kd ma motifs mutational p150glued particulate predicts proper q252a replication requirement reverse steps tctex transcriptase uncoating	10p11 a549 abundant actin bipartite bovine bu cdnas comparatively conservation cooh cytoskeleton deleted filaments gland headpiece hela identity message microvilli nh2 originally s3 salivary supervillin sw480 terminus tightly villin
Tagcloud (Difference) ?		1inq53a 250viqd 52gqvd adapter attempt capsid defective dynein hiv immunodeficiency integrase interaction kd ma motifs mutational p150glued particulate predicts proper q252a replication requirement reverse steps tctex transcriptase uncoating	10p11 a549 abundant actin bipartite bovine bu cdnas comparatively conservation cooh cytoskeleton deleted filaments gland headpiece hela identity message microvilli nh2 originally s3 salivary supervillin sw480 terminus tightly villin
Tagcloud (Intersection) ?