SYK and HDAC6

  • Number of citations of the paper that reports this interaction (PMID 16288017)
  • 14
  • Data Source:
  • BioGRID (affinity chromatography technology, pull down)

SYK

HDAC6

Gene Name spleen tyrosine kinase histone deacetylase 6
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 98 interactors: APP BLNK BTK CALM1 CBL CBLB CD19 CD22 CD3E CD72 CD79A CD79B CRKL CSF2RB CSF3R CTTN DBNL DUSP3 EGFR EPOR ERBB2 ERBB3 ERBB4 FCER1G FCGR1A FCGR2A FCGR3A FCRL3 FGR FYN GAB2 GRB2 HCLS1 HDAC1 HDAC2 HDAC3 HDAC4 HDAC6 HDAC9 HNRNPU IL15RA IL2RB ITGB2 JAK1 LAT LAX1 LCK LCP2 LYN MAP4K1 MAPK3 MAPT MS4A2 NEDD4 NFAM1 PAG1 PIK3AP1 PIK3R1 PIK3R2 PLCG1 PLCG2 POU2AF1 PRKCA PRKD1 PTK2 PTK2B PTPN6 PXN RASA1 RPS10 RPS6KA1 RPS6KB1 RPS6KB2 SELPLG SH2B2 SH2D2A SH3BP2 SHC1 SIT1 SLA SLC4A1 SNCA SRC STAT1 STAT3 STAT5A TERF1 TLR4 TNFRSF1A TRAF6 TUBA1A TUBA4A TYROBP UBASH3B UBB USP25 VAV1 VAV2 67 interactors: ADRB2 ADRBK1 ATF3 ATXN3 AURKA BBS10 BCL3 BCOR BRMS1 CDKN1A CORD1 CSNK2A2 CTNNB1 CTTN CYLD EP300 ERBB2 ERBB3 ERBB4 FBP1 FBXO11 FNTA FNTB G3BP1 HDAC11 HES1 HIST4H4 HSP90AA1 JDP2 KPNA1 LCOR LPXN MAPK3 NACAD NASP NR0B2 NR3C1 PKN1 PLAA POLA2 POLDIP2 POLR1B PPP1CC PRDX4 PTOV1 PXN RELB RUNX2 SIRT2 SYK TPPP TRIM50 TUBA1B TUBA4A TUBB TUBB2A TUBB2B UBB UBC UBE2D1 UBE2D3 UBE2E1 UBE2H VCP VKORC1 ZBTB16 ZNF205
Entrez ID 6850 10013
HPRD ID 02514 02228
Ensembl ID ENSG00000165025 ENSG00000094631
Uniprot IDs A8K4G2 P43405 Q9UBN7
PDB IDs 1A81 1CSY 1CSZ 1XBA 1XBB 1XBC 3BUW 3EMG 3FQE 3FQH 3FQS 3SRV 3TUB 3TUC 3TUD 3VF8 3VF9 4DFL 4DFN 4F4P 4FL1 4FL2 4FL3 4FYN 4FYO 4FZ6 4FZ7 4GFG 3C5K 3GV4 3PHD
Enriched GO Terms of Interacting Partners?
Tagcloud ?
belongs  bind  binds  blotting  coimmunoprecipitation  contribution  cytokine  domains  epo  epor  erythroid  erythropoietin  far  homology  individually  interaction  jak2  mediate  paper  participated  propose  recombinant  regulates  sh2  src  tandem  tyrosine  tyrosines  ut7 
amplification  classified  clinicopathological  correlated  deacetylase  deacetylation  ductal  entire  hdac1  hdac2  hdac3  hdacs  ihc  improved  luminal  microarrays  multiplication  oncogenic  os  progesterone  property  scoring  subtype  supporting  tumorigenesis  tumors  univariate  younger 
Tagcloud (Difference) ?
belongs  bind  binds  blotting  coimmunoprecipitation  contribution  cytokine  domains  epo  epor  erythroid  erythropoietin  far  homology  individually  interaction  jak2  mediate  paper  participated  propose  recombinant  regulates  sh2  src  tandem  tyrosine  tyrosines  ut7 
amplification  classified  clinicopathological  correlated  deacetylase  deacetylation  ductal  entire  hdac1  hdac2  hdac3  hdacs  ihc  improved  luminal  microarrays  multiplication  oncogenic  os  progesterone  property  scoring  subtype  supporting  tumorigenesis  tumors  univariate  younger 
Tagcloud (Intersection) ?