SSR1 and HSPA13

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		SSR1	HSPA13
Gene Name		signal sequence receptor, alpha	heat shock protein 70kDa family, member 13
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane	Endoplasmic Reticulum Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	ATP Binding
	Biological Process	Translation Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Cell Proliferation Gene Expression Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process
Pathways		IRE1alpha activates chaperones Translation SRP-dependent cotranslational protein targeting to membrane XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: DKC1 EEF1A1 HSPA13 NUP54 ODC1 PTN SERPINF2 UTP14A	8 interactors: BAG6 POLE4 RMI1 SGTA SSR1 UBQLN1 UBQLN2 UBQLN4
Entrez ID		6745	6782
HPRD ID		02924	03061
Ensembl ID		ENSG00000124783	ENSG00000155304
Uniprot IDs		E9PAL7 P43307	F5GWS8 P48723
PDB IDs
Enriched GO Terms of Interacting Partners?		Putrescine Biosynthetic Process From Ornithine RRNA Processing RRNA Metabolic Process Putrescine Biosynthetic Process Regulation Of Blood Vessel Size By Renin-angiotensin Ribosome Biogenesis Positive Regulation Of Cell Proliferation Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Ornithine Metabolic Process Negative Regulation Of Plasminogen Activation Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Negative Regulation Of Fibrinolysis	Response To Endoplasmic Reticulum Stress Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Reduction Of Food Intake In Response To Dietary Excess Regulation Of Cellular Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Establishment Of Protein Localization To Membrane Regulation Of Protein Metabolic Process Peptidyl-lysine Modification Protein Insertion Into ER Membrane
Tagcloud ?		3t3 a4 adipocytes antioxidants cyclic cytoprotection dismutase endoplasmic ern1 fabp4 glutathione gmp gsh gsta4 h2o2 kinds l1 lowering nitro orm1 ormdl3 peroxide reticulum scavenger sod spliced superoxide transferase xbp1s	apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspb10 hspb2 hspb3 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1
Tagcloud (Difference) ?		3t3 a4 adipocytes antioxidants cyclic cytoprotection dismutase endoplasmic ern1 fabp4 glutathione gmp gsh gsta4 h2o2 kinds l1 lowering nitro orm1 ormdl3 peroxide reticulum scavenger sod spliced superoxide transferase xbp1s	apg1 forelimb forelimbs grp94 hindlimb hindlimbs hsp10 hsp105 hsp110 hsp20 hsp22 hsp25 hsp47 hsp60 hspb10 hspb2 hspb3 hspb4 hspb7 hspb9 hsps oligodactylic performs phocomelic trap1
Tagcloud (Intersection) ?