SPIB and TMEM37

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SPIB	TMEM37
Gene Name		Spi-B transcription factor (Spi-1/PU.1 related)	transmembrane protein 37
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Integral Component Of Membrane
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Sequence-specific DNA Binding	Voltage-gated Ion Channel Activity Calcium Channel Activity
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Cell Differentiation	Regulation Of Ion Transmembrane Transport Calcium Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Primary biliary cirrhosis ( 21399635 20639880)
Protein-Protein Interactions		19 interactors: CEBPB CREBBP CSNK2A1 CSNK2A2 E2F1 E2F2 E2F3 E2F4 EP300 GATA1 IRF4 JUN MAPK3 MAPK8 RB1 SPI1 SSB TBP TMEM37	6 interactors: HBP1 MPP3 ORM1 PLA2G12A SPIB UBQLN1
Entrez ID		6689	140738
HPRD ID		06007	15536
Ensembl ID		ENSG00000269404	ENSG00000171227
Uniprot IDs		Q01892	E7EMC0 Q86SV2 Q8WXS4
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Gene Expression RNA Metabolic Process Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Apoptotic Process Programmed Cell Death Cell Death Nitrogen Compound Metabolic Process Death Positive Regulation Of Cellular Metabolic Process Biosynthetic Process Regulation Of Chromosome Organization DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Binding Mitotic Cell Cycle Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Binding Myeloid Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Immune System Process	Positive Regulation Of Chylomicron Remnant Clearance
Tagcloud ?		abc amplify attractive augmenting btk card11 cereblon dlbcl dlbcls downregulates fashion ibrutinib ifnbeta inspire irf4 irf7 killing kills lenalidomide lethal lymphomas myd88 owing prosurvival repressing sparing synergizes synthetically transactivating
Tagcloud (Difference) ?		abc amplify attractive augmenting btk card11 cereblon dlbcl dlbcls downregulates fashion ibrutinib ifnbeta inspire irf4 irf7 killing kills lenalidomide lethal lymphomas myd88 owing prosurvival repressing sparing synergizes synthetically transactivating
Tagcloud (Intersection) ?