SMN1 and POLR2A

  • Number of citations of the paper that reports this interaction (PMID 11149922)
  • 46
  • Data Source:
  • HPRD (in vivo)

SMN1

POLR2A

Gene Name survival of motor neuron 1, telomeric polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 136 interactors: A1BG A2M ACTB ACTL6B ADAMTS10 AGAP1 APLP1 ARFGAP1 ATP5B ATP6V1A BAG6 BCL2 C19orf60 CARHSP1 CCDC90B CENPB COIL COL4A2 COL4A5 COPS6 CPNE6 CRIP2 CSAD DDAH2 DDX20 DHX9 DMPK DOCK7 DUS2 DYNC1I1 EEF1A1 EIF3G EXT2 EZH2 FAM20C FBL FGB FLAD1 FUBP1 GAPDH GAR1 GDF9 GEMIN2 GEMIN5 GEMIN7 HADHB HIST3H3 HMGXB3 HNRNPR HNRNPU HNRNPUL1 IGHM ILF3 IMMT INPP5K JADE1 KDM1A KIF5A KLHL5 KMT2B KPNB1 LENG8 LRIF1 LSM1 LSM10 LSM11 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MAST2 MED31 MKI67 MPP1 MRPL37 MSH2 NGFR NKIRAS2 NMT2 OSTF1 PDE4DIP PKM PLXNA3 POLR2A POP7 PSME1 QARS RBBP4 RBBP6 RBFOX2 RBM48 RN7SL1 RNU1-1 RNU2-1 RPL13 RPS2 RXRA SDF4 SEMA5B SETDB1 SMC5 SMN2 SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNUPN SP110 STRAP STXBP2 STXBP3 SULT1A3 SUMO3 SYNCRIP TAF1C TIAL1 TLE1 TMSB4X TP53 TRMT2A TUBA1A TUBB3 UCHL1 UNC119 USP4 WDR18 WDR73 WDYHV1 WIZ ZBTB16 ZNF431 ZRANB2 ZXDC 100 interactors: ABL1 ACTB ACTL6A ATM BARD1 BRCA1 CASP10 CCNH CCNK CCNL2 CCNT1 CDC14A CDK12 CDK7 CDK8 CDK9 CPSF1 CPSF2 CPSF3 CREBBP CSH2 CSNK2A1 CSTF1 CSTF2 CTCF CTD CTDP1 CTDSP1 CTDSP2 DHX9 ELL ERCC5 ERCC6 ERG FCP1 FUS GRB2 GTF2B GTF2E1 GTF2H4 HIST1H1C HNRNPF HNRNPU HTATSF1 ITCH IWS1 KAT2B KLK2 KMT2D LEO1 MCM3 MED21 MNAT1 MYC NEDD4 NELFA NONO NR0B2 PCIF1 PHF8 PIN1 POLR2B POLR2C POLR2D POLR2E POLR2F POLR2G POLR2H POLR2I POLR2K POLR2L PPIG PPP1CA PQBP1 PRPF19 RECQL5 SAFB SETD2 SMN1 SMN2 SMURF1 SND1 SUB1 SUPT5H TAF10 TBP TCEA1 TCEB3 TCERG1 TRAK1 TRAM2 U2AF2 UBC UBE2L3 UPF1 WAC WWP2 XAB2 XRCC5 ZNF74
Entrez ID 6606 5430
HPRD ID 02646 08916
Ensembl ID ENSG00000172062 ENSG00000181222
Uniprot IDs B4DP61 Q16637 P24928
PDB IDs 1G5V 1MHN 2LEH 3S6N 4A4E 4A4G 4GLI 2GHQ 2GHT 2LTO 3D9K 3D9L 3D9M 3D9N 3D9O 3D9P
Enriched GO Terms of Interacting Partners?
Tagcloud ?
atrophy  centromeric  compensate  copies  copy  degeneration  deletions  detectable  display  donor  easily  exon  fails  fatal  harbor  hindering  homozygous  infant  intragenic  italian  modifier  muscular  null  predictable  sma  smn2  splice  unusually  weakness 
actb  appropriately  benchmark  chosen  confounding  gapdh  hormonal  hprt1  hyperglycemia  hyperglycemic  lean  myocardium  normalization  normalized  obesity  ppia  predisposition  reference  reproducibility  rpl13a  scrutiny  sdha  select  stably  tbp  tfrc  underline  ywhag  zucker 
Tagcloud (Difference) ?
atrophy  centromeric  compensate  copies  copy  degeneration  deletions  detectable  display  donor  easily  exon  fails  fatal  harbor  hindering  homozygous  infant  intragenic  italian  modifier  muscular  null  predictable  sma  smn2  splice  unusually  weakness 
actb  appropriately  benchmark  chosen  confounding  gapdh  hormonal  hprt1  hyperglycemia  hyperglycemic  lean  myocardium  normalization  normalized  obesity  ppia  predisposition  reference  reproducibility  rpl13a  scrutiny  sdha  select  stably  tbp  tfrc  underline  ywhag  zucker 
Tagcloud (Intersection) ?