SLC1A7 and ZNF420

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SLC1A7	ZNF420
Gene Name		solute carrier family 1 (glutamate transporter), member 7	zinc finger protein 420
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane	Nucleus Extracellular Vesicular Exosome
	Molecular Function	L-glutamate Transmembrane Transporter Activity Sodium:dicarboxylate Symporter Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Ion Transport Dicarboxylic Acid Transport Transmembrane Transport L-glutamate Transmembrane Transport	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Neurotransmitter Release Cycle Transport of inorganic cations/anions and amino acids/oligopeptides SLC-mediated transmembrane transport Glutamate Neurotransmitter Release Cycle Transmission across Chemical Synapses	Generic Transcription Pathway
Drugs
Diseases
GWAS		Hippocampal atrophy ( 22745009) Systemic lupus erythematosus ( 21408207)
Protein-Protein Interactions		2 interactors: SNTA1 ZNF420	8 interactors: CDC42 CDK2AP1 CYP4V2 CYP51A1 HAX1 SLC1A7 TNFRSF1B TRIM28
Entrez ID		6512	147923
HPRD ID		09194	08122
Ensembl ID		ENSG00000162383	ENSG00000197050
Uniprot IDs		F1T0D4 O00341 Q9BW45	Q8TAQ5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Vasoconstriction By Circulating Norepinephrine Negative Regulation Of Peptidyl-cysteine S-nitrosylation Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Ventricular Cardiac Muscle Cell Action Potential Regulation Of Membrane Repolarization Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Sodium Ion Transmembrane Transport Cardiac Muscle Cell Action Potential Regulation Of Cardiac Muscle Cell Contraction Neuromuscular Junction Development Regulation Of Vasoconstriction Regulation Of Sodium Ion Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Regulation Of Striated Muscle Contraction Action Potential	Regulation Of Intracellular Protein Transport Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Intracellular Transport Cholesterol Biosynthetic Process Via 24,25-dihydrolanosterol Positive Regulation Of Protein Metabolic Process Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Cellular Metabolic Process Negative Regulation Of DNA Demethylation Positive Regulation Of Hair Follicle Cell Proliferation Fatty Acid Omega-oxidation Regulation Of Protein Transport Actin Filament Branching Submandibular Salivary Gland Formation Positive Regulation Of DNA Metabolic Process Regulation Of Establishment Of Protein Localization Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Targeting To Mitochondrion Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Positive Regulation Of Protein Phosphorylation Convergent Extension Involved In Axis Elongation Regulation Of Protein Localization Establishment Of Golgi Localization Regulation Of Genetic Imprinting DNA Methylation Involved In Embryo Development Positive Regulation Of Metalloenzyme Activity Positive Regulation Of Phosphorylation Positive Regulation Of Metabolic Process Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Modification Process Positive Regulation Of Intracellular Transport Neuron Fate Determination Epithelial-mesenchymal Cell Signaling Positive Regulation Of Granulocyte Differentiation Regulation Of Protein Heterodimerization Activity Regulation Of Mitochondrion Degradation Keratinocyte Development Regulation Of Synapse Structural Plasticity Regulation Of Protein Metabolic Process Regulation Of Cellular Localization Regulation Of Protein Phosphorylation Positive Regulation Of Pseudopodium Assembly Nuclear Migration RNA Destabilization Cardiac Conduction System Development Convergent Extension Positive Regulation Of Membrane Protein Ectodomain Proteolysis Golgi Localization Negative Regulation Of Viral Release From Host Cell
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