SHBG and ACPP

Number of citations of the paper that reports this interaction (PMID 15862967)
1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SHBG	ACPP
Gene Name		sex hormone-binding globulin	acid phosphatase, prostate
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Vesicular Exosome	Extracellular Space Intracellular Nucleus Lysosomal Membrane Multivesicular Body Plasma Membrane Vesicle Membrane Integral Component Of Membrane Secretory Granule Filopodium Golgi Cisterna Apical Part Of Cell Extracellular Vesicular Exosome
	Molecular Function	Androgen Binding	Acid Phosphatase Activity 5'-nucleotidase Activity Phosphatase Activity Choline Binding Thiamine Phosphate Phosphatase Activity Identical Protein Binding Protein Homodimerization Activity Lysophosphatidic Acid Phosphatase Activity
	Biological Process	Primary Spermatocyte Growth	Purine Nucleobase Metabolic Process Thiamine Metabolic Process Nucleotide Metabolic Process Dephosphorylation Adenosine Metabolic Process Regulation Of Sensory Perception Of Pain Positive Regulation Of Adenosine Receptor Signaling Pathway
Pathways
Drugs			Alpha-D-Mannose N-Propyl-Tartramic Acid Alpha-Benzyl-Aminobenzyl-Phosphonic Acid
Diseases
GWAS		Androgen levels ( 22936694) Protein quantitative trait loci ( 18464913) Sex hormone-binding globulin levels ( 22675492 22829776) Testosterone levels ( 21998597)
Protein-Protein Interactions		62 interactors: A2M ACPP ACTA2 ACTB ACTG2 AK2 AKR1B1 AP1B1 AP2A1 APEH APOBEC3C APOD ASB16-AS1 ATP5A1 AZGP1 C9orf24 CD177 CECR5 CEP192 CLDN4 CLEC4G COL1A2 CTSD DDX3Y DES DSTN EEF1A1 EIF3E EIF3F FLNA FLOT1 FYTTD1 GRB2 HYI JMJD7-PLA2G4B KLK4 MPDU1 MT1F MT1G MT2A MXD4 NOMO1 PACSIN2 PKM PLA2G4A PLP2 PSTPIP1 PSTPIP2 PTGDS RMND5B SEMA3F SLC37A1 SLC37A4 SNAPIN SNRNP70 SORD SRF SRI TINAGL1 UBE2O UBE3A ZC3H12A	2 interactors: ERBB2 SHBG
Entrez ID		6462	55
HPRD ID		01646	01378
Ensembl ID		ENSG00000129214	ENSG00000014257
Uniprot IDs		B0FWH2 B4DYU0 I3L1J1 I3L2X4 P04278	P15309
PDB IDs		1D2S 1F5F 1KDK 1KDM 1LHN 1LHO 1LHU 1LHV 1LHW	1CVI 1ND5 1ND6 2HPA 2L3H 2L77 2L79 3PPD
Enriched GO Terms of Interacting Partners?		Platelet Activation Extracellular Matrix Disassembly Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Cellular Response To Zinc Ion Endocytosis Vesicle-mediated Transport Response To Wounding Transport Endosomal Transport Cell Activation Response To Zinc Ion Cell Projection Organization Immune System Process MRNA Transcription From RNA Polymerase II Promoter Glucose Metabolic Process MRNA Transcription Neuron Projection Development Movement Of Cell Or Subcellular Component Cellular Response To Cadmium Ion Regulation Of Water Loss Via Skin Formation Of Translation Preinitiation Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Cell Morphogenesis Involved In Differentiation Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Receptor-mediated Endocytosis Hexose Metabolic Process Neuron Development Extracellular Matrix Organization Viral Process Cytoplasmic Sequestering Of Protein Regulation Of Defense Response To Virus By Virus Extracellular Structure Organization Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Axon Development Antigen Processing And Presentation Of Peptide Antigen Locomotion Negative Regulation Of Growth Monosaccharide Metabolic Process Sperm Entry Negative Regulation Of T Cell Migration Contractile Actin Filament Bundle Assembly Negative Regulation Of Lipoprotein Lipid Oxidation Positive Regulation Of Late Endosome To Lysosome Transport Sorbitol Catabolic Process L-xylitol Metabolic Process L-xylitol Catabolic Process Fructose Biosynthetic Process	Primary Spermatocyte Growth Negative Regulation Of Immature T Cell Proliferation In Thymus Negative Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Transcription From RNA Polymerase III Promoter Positive Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Transcription From RNA Polymerase I Promoter Regulation Of Transcription From RNA Polymerase III Promoter Phosphatidylinositol 3-kinase Signaling Regulation Of T Cell Differentiation In Thymus Motor Neuron Axon Guidance Negative Regulation Of T Cell Differentiation
Tagcloud ?		asgr assigned chr distances f1 grin grin1 grin2a grin2b grin2c grin2d grm grm1 grm2 grm3 grm4 grm5 grm6 linkage maps metabotropic mmyhse myhse ppy rr24 shr symbol wtc zi	aacr acpps aggressiveness carrying choroid clin cn copies cpc cpcs cpps cpt cpts disomy distinguished efs entity hyperdiploid hypodiploid institutional papillomas plexus refine res signatures stratification subgroups uniparental
Tagcloud (Difference) ?		asgr assigned chr distances f1 grin grin1 grin2a grin2b grin2c grin2d grm grm1 grm2 grm3 grm4 grm5 grm6 linkage maps metabotropic mmyhse myhse ppy rr24 shr symbol wtc zi	aacr acpps aggressiveness carrying choroid clin cn copies cpc cpcs cpps cpt cpts disomy distinguished efs entity hyperdiploid hypodiploid institutional papillomas plexus refine res signatures stratification subgroups uniparental
Tagcloud (Intersection) ?