S100A13 and PHYHIP

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		S100A13	PHYHIP
Gene Name		S100 calcium binding protein A13	phytanoyl-CoA 2-hydroxylase interacting protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Cytosol Mast Cell Granule Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Copper Ion Binding Calcium Ion Binding Protein Binding Zinc Ion Binding Lipid Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity RAGE Receptor Binding
	Biological Process	Positive Regulation Of Cell Proliferation Regulation Of Cell Shape Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Mast Cell Degranulation Response To Copper Ion Cytokine Secretion Interleukin-1 Alpha Secretion Response To Electrical Stimulus
Pathways
Drugs		Olopatadine Amlexanox
Diseases
GWAS			Hypertriglyceridemia ( 23505323)
Protein-Protein Interactions		7 interactors: FGF1 IGBP1 IL1A IRF9 PHYHIP PLEKHF2 SYT1	24 interactors: BAI1 C14orf1 COPS6 DYRK1A EEF1A1 FAM131A HDAC11 HNRNPA1 MAGED4B MED8 METTL18 NDRG1 NDUFV3 NFE2 PHYH PNPLA2 PPIE PRMT5 S100A13 SMARCC2 SUPT5H TTR WDR89 ZZEF1
Entrez ID		6284	9796
HPRD ID		03586	16345
Ensembl ID		ENSG00000189171	ENSG00000168490
Uniprot IDs		Q99584	Q92561
PDB IDs		1YUR 1YUS 1YUT 1YUU 2EGD 2H2K 2K8M 2KI4 2KI6 2KOT 2L5X 2LE9
Enriched GO Terms of Interacting Partners?		Cellular Response To Heat Branch Elongation Involved In Ureteric Bud Branching Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Response To Heat Regulation Of MAPK Cascade Positive Regulation Of Angiogenesis Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Cell Division Response To Cytokine Immune System Process Regulation Of Stress-activated MAPK Cascade Response To Temperature Stimulus Regulation Of ERK1 And ERK2 Cascade Fever Generation Calcium Ion-dependent Exocytosis Of Neurotransmitter Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Ureteric Bud Elongation Regulation Of Angiogenesis Negative Regulation Of Protein Dephosphorylation Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Organic Substance Heat Generation Negative Regulation Of Apoptotic Signaling Pathway Regulation Of Cell Division Wound Healing Involved In Inflammatory Response Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Cholesterol Metabolic Process Positive Regulation Of Secretion Response To Metal Ion Type I Interferon Biosynthetic Process Immune Response Regulation Of Phosphorylation Detection Of Calcium Ion Positive Regulation Of Transcription, DNA-templated Defense Response Regulation Of Signaling Ectopic Germ Cell Programmed Cell Death Positive Regulation Of Calcium Ion-dependent Exocytosis Regulation Of Microtubule-based Movement Signaling Positive Regulation Of Interleukin-2 Biosynthetic Process Cell Communication Type I Interferon Production Positive Regulation Of Organelle Organization Regulation Of Phosphorus Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Vesicle Fusion Positive Regulation Of Gene Expression Positive Regulation Of MAPK Cascade	Nucleosome Disassembly Chromatin Organization Mast Cell Activation MRNA Processing RNA Metabolic Process Cellular Metabolic Process MRNA Metabolic Process MRNA Splicing, Via Spliceosome Interleukin-1 Alpha Secretion RNA Splicing, Via Transesterification Reactions Gene Expression RNA Processing Chromosome Organization Chromatin Modification Positive Regulation Of Viral Process Nucleobase-containing Compound Metabolic Process Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Methyl-branched Fatty Acid Metabolic Process Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Transcription, DNA-templated RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Splicing Glial Cell Development Peripheral Nervous System Development Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Acylglycerol Acyl-chain Remodeling Thyroid Hormone Transport Isoprenoid Metabolic Process Fatty Acid Alpha-oxidation Interleukin-1 Secretion Positive Regulation Of Spindle Checkpoint Regulation Of RNA Metabolic Process
Tagcloud ?		anchor bilayer biophysical biphasic c2b calorimetry cu2 destabilized endothermic exothermic fgf1 isothermal itc lacks marginally mrc multiprotein nonclassical p40 phosphatidyl pockets proangiogenic ps synaptotagmin syt1 tb3 titration unilamellar vesicles
Tagcloud (Difference) ?		anchor bilayer biophysical biphasic c2b calorimetry cu2 destabilized endothermic exothermic fgf1 isothermal itc lacks marginally mrc multiprotein nonclassical p40 phosphatidyl pockets proangiogenic ps synaptotagmin syt1 tb3 titration unilamellar vesicles
Tagcloud (Intersection) ?