S100A8 and CEACAM3

Number of citations of the paper that reports this interaction (PMID 11708798)
2

Data Source:
HPRD (in vivo)

		S100A8	CEACAM3
Gene Name		S100 calcium binding protein A8	carcinoembryonic antigen-related cell adhesion molecule 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytosol Cytoskeleton Plasma Membrane Extracellular Vesicular Exosome	Integral Component Of Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Microtubule Binding Zinc Ion Binding Toll-like Receptor 4 Binding Arachidonic Acid Binding RAGE Receptor Binding
	Biological Process	Cytokine Production Leukocyte Migration Involved In Inflammatory Response Acute Inflammatory Response Chronic Inflammatory Response Positive Regulation Of Peptide Secretion Autophagy Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Inflammatory Response Response To Zinc Ion Positive Regulation Of Cell Growth Neutrophil Chemotaxis Sequestering Of Zinc Ion Response To Lipopolysaccharide Chemokine Production Wound Healing Defense Response To Bacterium Innate Immune Response Response To Ethanol Positive Regulation Of Inflammatory Response Defense Response To Fungus Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cytoskeleton Organization Neutrophil Aggregation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: APP C14orf1 CDKN1A CEACAM3 CHGB GDF9 IGSF21 KLC2 LRIF1 NCF2 PDCD11 PPIA PRMT1 RAB17 S100A9 TP53 TUBA4A UNC119	4 interactors: CEACAM1 CSNK1A1L S100A8 SRC
Entrez ID		6279	1084
HPRD ID		00471	16450
Ensembl ID		ENSG00000143546	ENSG00000170956
Uniprot IDs		P05109	G5E978 P40198
PDB IDs		1MR8 1XK4 4GGF
Enriched GO Terms of Interacting Partners?		Blood Coagulation Hemostasis Platelet Degranulation Immune System Process Stress-induced Premature Senescence Regulation Of Body Fluid Levels Wound Healing Regulation Of Growth Mitotic Cell Cycle Arrest Positive Regulation Of Cellular Protein Metabolic Process Response To Light Stimulus Response To Wounding Regulation Of Cell Growth Positive Regulation Of Protein Metabolic Process Immune Response Negative Regulation Of Cell Growth Response To Radiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To X-ray Cellular Senescence Response To Hyperoxia Platelet Activation Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Mitotic Cell Cycle Phase Transition Ras Protein Signal Transduction Positive Regulation Of Cell Cycle Process Regulation Of Protein Phosphorylation Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Cell Cycle Phase Transition Response To Stimulus Response To Abiotic Stimulus Positive Regulation Of Programmed Cell Death Axon Cargo Transport Negative Regulation Of Growth Response To Stress Positive Regulation Of Cell Death Response To External Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Neuron Apoptotic Process Cellular Response To Ionizing Radiation Signal Transduction Involved In DNA Damage Checkpoint Positive Regulation Of Neuron Apoptotic Process Signal Transduction Involved In Cell Cycle Checkpoint Cellular Response To UV Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Cell Cycle Negative Regulation Of Clathrin-mediated Endocytosis Uncoating Of Virus Mitotic Cell Cycle Process	Leukocyte Migration Wound Healing Response To Wounding Peptidyl-serine Phosphorylation Integrin-mediated Signaling Pathway Cell Migration Cell Motility Regulation Of Intrinsic Apoptotic Signaling Pathway Neutrophil Aggregation Cellular Response To Progesterone Stimulus Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Cell Adhesion Locomotion Sequestering Of Zinc Ion Phagocytosis Positive Regulation Of Integrin Activation Negative Regulation Of Mitochondrial Depolarization Positive Regulation Of Podosome Assembly Negative Regulation Of Protein Homooligomerization Progesterone Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Response To Lipopolysaccharide Regulation Of Podosome Assembly Positive Regulation Of Secretion Response To Molecule Of Bacterial Origin Regulation Of Caveolin-mediated Endocytosis Osteoclast Development Negative Regulation Of Protein Oligomerization Regulation Of Endopeptidase Activity Chemokine Production Sequestering Of Metal Ion Regulation Of Peptidase Activity Regulation Of Integrin Activation Blood Coagulation Hemostasis Regulation Of Early Endosome To Late Endosome Transport Regulation Of Cellular Component Organization Transcytosis Chronic Inflammatory Response Response To Inorganic Substance Signal Complex Assembly Stress Fiber Assembly Cellular Zinc Ion Homeostasis Response To Bacterium Negative Regulation Of Anoikis Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Autophosphorylation Uterus Development
Tagcloud ?		a9 auscan australian canadian erythrocyte esr exploratory grades hand hip inverse joint kellgren knee lawrence mcmaster narrowing oa ontario osteoarthritis osteophytes sedimentation space stiffness structural sum synovial universities womac	associating crkl directs engagement engulfment gef guanine immunoreceptor interfere internalization itam knock lamellipodial nap1 nck nck1 nck2 nucleation opsonin ordinate phagocytosis protrusions rac sh2 slp vav wave wave2
Tagcloud (Difference) ?		a9 auscan australian canadian erythrocyte esr exploratory grades hand hip inverse joint kellgren knee lawrence mcmaster narrowing oa ontario osteoarthritis osteophytes sedimentation space stiffness structural sum synovial universities womac	associating crkl directs engagement engulfment gef guanine immunoreceptor interfere internalization itam knock lamellipodial nap1 nck nck1 nck2 nucleation opsonin ordinate phagocytosis protrusions rac sh2 slp vav wave wave2
Tagcloud (Intersection) ?