RXRB and TAF11

Number of citations of the paper that reports this interaction (PMID 8670810)
25

Data Source:
HPRD (in vivo)

		RXRB	TAF11
Gene Name		retinoid X receptor, beta	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleoplasm Transcription Factor TFIID Complex Golgi Apparatus
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Transcription Coactivator Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity 9-cis Retinoic Acid Receptor Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity	DNA Binding Transcription Coactivator Activity Protein Binding Vitamin D Receptor Binding Thyroid Hormone Receptor Binding Protein Heterodimerization Activity Protein N-terminus Binding
	Biological Process	In Utero Embryonic Development Maternal Placenta Development Transcription Initiation From RNA Polymerase II Promoter Gene Expression Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Retinoic Acid Receptor Signaling Pathway Ventricular Cardiac Muscle Cell Differentiation Transmembrane Transport Cardiac Muscle Cell Proliferation Cellular Response To Retinoic Acid	Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Positive Regulation By Host Of Viral Transcription
Pathways		Generic Transcription Pathway Signaling by Retinoic Acid Nuclear Receptor transcription pathway Orphan transporters	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs		Adapalene Bexarotene Acitretin Alitretinoin Tretinoin Tazarotene Etretinate 6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-Tetrahydronaphthalen-2-Yl)Cyclopropyl]Pyridine-3-Carboxylic Acid N-(2,2,2-TRIFLUOROETHYL)-N-{4-[2,2,2-TRIFLUORO-1-HYDROXY-1-(TRIFLUOROMETHYL)ETHYL]PHENYL}BENZENESULFONAMIDE N-(TERT-BUTYL)-3,5-DIMETHYL-N\'-[(5-METHYL-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)CARBONYL]BENZOHYDRAZIDE (2E,4E)-11-METHOXY-3,7,11-TRIMETHYLDODECA-2,4-DIENOIC ACID
Diseases
GWAS		Wegener's granulomatosis ( 23740775)
Protein-Protein Interactions		32 interactors: AKAP13 CACNA1B GRIP1 GTF2H1 MAP4 MED1 NCOA1 NCOA3 NR0B2 NR1H2 NR1H3 NR1I2 NR2C2 NR2E3 NR3C1 NR4A2 NRIP1 PPARD PPARG PTMS RARA RARB RARG SPOP SRA1 SRC TACC2 TAF11 THRA THRB VDR ZDHHC12	28 interactors: APP APPBP2 CPSF1 GTF2B GTF2E1 GTF2F1 HIST3H3 LZTR1 NFYA NFYB NFYC RELA RXRA RXRB TAF1 TAF10 TAF12 TAF13 TAF2 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP TRIM24 VDR
Entrez ID		6257	6882
HPRD ID		01578	15980
Ensembl ID		ENSG00000204231	ENSG00000064995
Uniprot IDs		E9PK95 P28702 Q5STP9	Q15544
PDB IDs		1H9U 1UHL	1BH8 1BH9
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Cellular Response To Steroid Hormone Stimulus DNA-templated Transcription, Initiation Cellular Response To Hormone Stimulus Response To Steroid Hormone Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Response To Hormone Positive Regulation Of Cellular Biosynthetic Process Response To Lipid Response To Organic Cyclic Compound Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway RNA Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Response To Organic Substance Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Apoptotic Process Regulation Of Cell Death	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Viral Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Metabolic Process Peptidyl-lysine Modification Regulation Of Cellular Process Maternal Placenta Development Histone H3 Acetylation Cellular Response To Steroid Hormone Stimulus Histone Modification Cellular Response To Organic Cyclic Compound Maternal Process Involved In Female Pregnancy Cellular Response To Lipid
Tagcloud ?		2riibp aa acceptor bands cdnas coding cpg deduced designated exons extra finger heterodimers intron island isoforms midst mrxr northern phylogenic spleen spliced splicing superfamily transactivation transcribed twofold zinc	autosomal copy ct47 d4z4 dystrophy euchromatic extreme facioscapulohumeral governed h3k27me3 h3k9me3 heterochromatic heterochromatinization hypermethylation leaky lymphoblastoid macrosatellite msrs muscular organized originating prr20 repressive testis trimethylated trimethylation understudied xq24 zav
Tagcloud (Difference) ?		2riibp aa acceptor bands cdnas coding cpg deduced designated exons extra finger heterodimers intron island isoforms midst mrxr northern phylogenic spleen spliced splicing superfamily transactivation transcribed twofold zinc	autosomal copy ct47 d4z4 dystrophy euchromatic extreme facioscapulohumeral governed h3k27me3 h3k9me3 heterochromatic heterochromatinization hypermethylation leaky lymphoblastoid macrosatellite msrs muscular organized originating prr20 repressive testis trimethylated trimethylation understudied xq24 zav
Tagcloud (Intersection) ?