FKBP10 and SLC2A4

Number of citations of the paper that reports this interaction (PMID 16396496)
24

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		FKBP10	SLC2A4
Gene Name		FK506 binding protein 10, 65 kDa	solute carrier family 2 (facilitated glucose transporter), member 4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane	Multivesicular Body Cytosol Plasma Membrane Integral Component Of Plasma Membrane Coated Pit External Side Of Plasma Membrane Endomembrane System Vesicle Membrane Membrane Clathrin-coated Vesicle Trans-Golgi Network Transport Vesicle T-tubule Insulin-responsive Compartment Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding FK506 Binding	Glucose Transmembrane Transporter Activity Protein Binding D-glucose Transmembrane Transporter Activity
	Biological Process	Protein Peptidyl-prolyl Isomerization Chaperone-mediated Protein Folding	Carbohydrate Metabolic Process Hexose Transport Pathogenesis Amylopectin Biosynthetic Process Glucose Transport Cellular Response To Insulin Stimulus Glucose Homeostasis Small Molecule Metabolic Process Response To Ethanol Glucose Import Brown Fat Cell Differentiation Transmembrane Transport Membrane Organization Cellular Response To Hypoxia Cellular Response To Osmotic Stress
Pathways			Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Translocation of GLUT4 to the plasma membrane SLC-mediated transmembrane transport Hexose transport Myoclonic epilepsy of Lafora Transcriptional regulation of white adipocyte differentiation Facilitative Na+-independent glucose transporters Glycogen storage diseases Glucose transport Metabolism of carbohydrates
Drugs
Diseases
GWAS			Birth weight ( 23202124) Metabolite levels ( 22286219)
Protein-Protein Interactions		2 interactors: ELN SLC2A4	38 interactors: ACOX1 ACTN1 ACTN4 AKT2 ARF3 ARFIP1 BSG C1QTNF5 CCDC116 CFL1 CTSD DAXX DLD EHD2 ESYT2 FAR1 FKBP10 GAPDH HADH HK2 HSP90AA1 IDH2 KLHL41 LNPEP MAP1S MVP P3H1 P3H4 PDIA6 PRKAR1A PSMD7 RAB7A SERPINH1 SRFBP1 STRN3 UBA52 UBE2I UBE2N
Entrez ID		60681	6517
HPRD ID		09522	00688
Ensembl ID		ENSG00000141756	ENSG00000181856
Uniprot IDs		Q658U4 Q8NAG5 Q96AY3	P14672 Q05BQ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Amylopectin Biosynthetic Process Glucose Import Stress Fiber Assembly Hexose Transmembrane Transport Cellular Response To Osmotic Stress Brown Fat Cell Differentiation Blood Vessel Remodeling Respiratory Gaseous Exchange Carbohydrate Transmembrane Transport Glucose Transport Actin Filament Bundle Assembly Hexose Transport Response To Osmotic Stress Extracellular Matrix Disassembly Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Actomyosin Structure Organization Tissue Remodeling Carbohydrate Transport Fat Cell Differentiation	Generation Of Precursor Metabolites And Energy Catabolic Process Protein Localization To Tight Junction Protein Transport Establishment Of Protein Localization Protein Localization Small Molecule Metabolic Process Organelle Organization Positive Regulation Of Transferase Activity Monocarboxylic Acid Metabolic Process Regulation Of Body Fluid Levels Antigen Processing And Presentation Of Peptide Antigen Protein Targeting Blood Coagulation Hemostasis Pyruvate Metabolic Process Intracellular Protein Transport Oxidation-reduction Process Response To Stress Protein Localization To Cell Junction Glucose Metabolic Process Antigen Processing And Presentation Regulation Of Cellular Protein Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Establishment Of Localization In Cell Protein Polyubiquitination Response To Stimulus Cellular Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Response To Organic Substance Cytoskeleton Organization Protein Localization To Membrane Platelet Degranulation Immune System Process Vesicle-mediated Transport Protein Ubiquitination Regulation Of Protein Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Extracellular Matrix Organization Extracellular Structure Organization Collagen Metabolic Process Membrane Organization Actin Cytoskeleton Organization Positive Regulation Of Ligase Activity Intracellular Receptor Signaling Pathway Transport Wound Healing Multicellular Organismal Macromolecule Metabolic Process Protein Metabolic Process Regulation Of Protein Ubiquitination
Tagcloud ?		biology calorie chaperone chaperones collectively commenced dampens defective downregulated driven endoplasmic exploited feeding hcd hinder imposed kras onset parenchyma reversed selectively shed surprising unexpected unfolded unravel unresolved upr vulnerabilities	atp1a2 atp1b2 beef corpus cows diestrus follicle glandular gonadotropin lcl lf luteum manipulated nelore ovulation p4 periovulatory pof preovulatory proestrus receptivity slaughtered slc5a1 washings
Tagcloud (Difference) ?		biology calorie chaperone chaperones collectively commenced dampens defective downregulated driven endoplasmic exploited feeding hcd hinder imposed kras onset parenchyma reversed selectively shed surprising unexpected unfolded unravel unresolved upr vulnerabilities	atp1a2 atp1b2 beef corpus cows diestrus follicle glandular gonadotropin lcl lf luteum manipulated nelore ovulation p4 periovulatory pof preovulatory proestrus receptivity slaughtered slc5a1 washings
Tagcloud (Intersection) ?