RNH1 and RNASE1

Number of citations of the paper that reports this interaction (PMID 9311977)
41

Data Source:
HPRD (in vitro)

		RNH1	RNASE1
Gene Name		ribonuclease/angiogenin inhibitor 1	ribonuclease, RNase A family, 1 (pancreatic)
Image
Gene Ontology Annotations	Cellular Component	Cytoplasm Angiogenin-PRI Complex Extracellular Vesicular Exosome	Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Ribonuclease Inhibitor Activity	Nucleic Acid Binding Pancreatic Ribonuclease Activity Protein Binding
	Biological Process	MRNA Catabolic Process Negative Regulation Of Catalytic Activity Regulation Of Angiogenesis	RNA Phosphodiester Bond Hydrolysis, Endonucleolytic
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		3 interactors: ANG RNASE1 SDCBP	2 interactors: RELA RNH1
Entrez ID		6050	6035
HPRD ID		01412	01591
Ensembl ID		ENSG00000023191	ENSG00000129538
Uniprot IDs		P13489	P07998
PDB IDs		1A4Y 1Z7X 2BEX 2Q4G	1DZA 1E21 1H8X 1Z7X 2E0J 2E0L 2E0M 2E0O 2K11 2Q4G 3F8G 4KXH
Enriched GO Terms of Interacting Partners?		RNA Phosphodiester Bond Hydrolysis Diacylglycerol Biosynthetic Process Positive Regulation Of Extracellular Vesicular Exosome Assembly Activation Of Phospholipase A2 Activity Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of Secretion Positive Regulation Of Phospholipase A2 Activity Regulation Of Extracellular Vesicular Exosome Assembly Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Substrate-dependent Cell Migration, Cell Extension Regulation Of Phospholipase A2 Activity Actin Cytoskeleton Organization Regulation Of Secretion Actin Filament-based Process Diacylglycerol Metabolic Process Positive Regulation Of Transport RRNA Transcription Oocyte Maturation Positive Regulation Of Organelle Assembly Activation Of Protein Kinase B Activity Cell Migration Positive Regulation Of Phosphorylation Cell Motility Substrate-dependent Cell Migration Negative Regulation Of Smooth Muscle Cell Proliferation Regulation Of Cellular Localization Actin Filament Polymerization Oocyte Development Oocyte Differentiation Activation Of Phospholipase C Activity Cytoskeleton Organization Positive Regulation Of Phospholipase C Activity Positive Regulation Of Exocytosis Positive Regulation Of Endothelial Cell Proliferation Locomotion Ovarian Follicle Development Regulation Of Phosphorylation RNA Phosphodiester Bond Hydrolysis, Endonucleolytic	Acetaldehyde Metabolic Process Positive Regulation Of Schwann Cell Differentiation Regulation Of Schwann Cell Differentiation Response To Cobalamin Positive Regulation Of MiRNA Metabolic Process Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Cellular Response To Nicotine Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of MiRNA Metabolic Process Mitochondrial DNA Replication Regulation Of Interleukin-12 Biosynthetic Process Response To Muramyl Dipeptide Response To UV-B Transcription From RNA Polymerase II Promoter Membrane Protein Intracellular Domain Proteolysis Mitochondrial DNA Metabolic Process Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Interleukin-6 Positive Regulation Of Chondrocyte Differentiation Mitochondrial Genome Maintenance Response To Interleukin-6 Membrane Protein Proteolysis Negative Regulation Of Insulin Receptor Signaling Pathway Positive Regulation Of Glial Cell Differentiation Response To Morphine Response To Nicotine Termination Of RNA Polymerase II Transcription Cellular Response To Alkaloid Positive Regulation Of Cartilage Development Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway NIK/NF-kappaB Signaling Positive Regulation Of Interleukin-12 Production Response To Progesterone Positive Regulation Of Gliogenesis Toll-like Receptor 5 Signaling Pathway Cellular Defense Response Toll-like Receptor 10 Signaling Pathway Cellular Response To Interleukin-1 Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Cellular Response To Hydrogen Peroxide Toll-like Receptor 9 Signaling Pathway Regulation Of Insulin Receptor Signaling Pathway Regulation Of Interleukin-12 Production TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Cytokine Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Chondrocyte Differentiation
Tagcloud ?			alarm amplify antithrombotic coagulation come contact counteracted defence dnase eliminate enduring exhibits expelled inducers innate links macromolecules nucleic nucleosome oedema pathogenetic permeability provokes summarizes thrombosis thrombus vasogenic venous vessel
Tagcloud (Difference) ?			alarm amplify antithrombotic coagulation come contact counteracted defence dnase eliminate enduring exhibits expelled inducers innate links macromolecules nucleic nucleosome oedema pathogenetic permeability provokes summarizes thrombosis thrombus vasogenic venous vessel
Tagcloud (Intersection) ?