RNF5 and ABHD16A

Number of citations of the paper that reports this interaction (PMID 14667819)
24

Data Source:
HPRD (two hybrid)

		RNF5	ABHD16A
Gene Name		ring finger protein 5, E3 ubiquitin protein ligase	abhydrolase domain containing 16A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondrial Membrane	Integral Component Of Membrane
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity	Hydrolase Activity
	Biological Process	Response To Bacterium Negative Regulation Of Autophagy Protein Destabilization Cellular Protein Catabolic Process Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination ER-associated Misfolded Protein Catabolic Process Regulation Of Autophagic Vacuole Assembly	Metabolic Process
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)
Protein-Protein Interactions		32 interactors: ABHD16A CFTR CYB561 CYB561A3 FHOD1 INSIG2 JKAMP MAVS MPDZ PXN RNF185 SEC22A SLC1A1 SLC38A7 TGFBR1 TMEM242 TNFAIP3 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2G2 UBE2K UBE2N UBE2U UBE2V1 UBE2W UBE2Z YIPF2	19 interactors: ATP5G3 DNAJC1 DTX2 FAM134C GPRC5C HM13 HNRNPA1 IFITM1 MLH1 ND3 ND4 PILRB PTGS2 RNF5 SAFB SPAG7 TMEM147 TMEM222 UPF1
Entrez ID		6048	7920
HPRD ID		04057	15929
Ensembl ID		ENSG00000204308	ENSG00000204427
Uniprot IDs		Q99942	B3KNX9 O95870
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Activation Of Innate Immune Response Protein K63-linked Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Positive Regulation Of Innate Immune Response Cellular Protein Modification Process Regulation Of Innate Immune Response Cellular Macromolecule Catabolic Process Toll-like Receptor 4 Signaling Pathway Cellular Protein Metabolic Process Cellular Response To Stress Toll-like Receptor Signaling Pathway Proteolysis Immune Response-regulating Signaling Pathway Protein Metabolic Process Response To Stress Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of Protein Ubiquitination Catabolic Process Positive Regulation Of Immune Response Histone Ubiquitination Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Protein Monoubiquitination Response To Organic Substance Negative Regulation Of Type I Interferon Production ISG15-protein Conjugation Aspartate Transport Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Innate Immune Response Regulation Of DNA-templated Transcription In Response To Stress Cellular Response To Organic Substance TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Immune Response Cellular Response To Transforming Growth Factor Beta Stimulus MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway	Respiratory Electron Transport Chain Electron Transport Chain ATP Metabolic Process Cellular Respiration Mitochondrial Electron Transport, NADH To Ubiquinone Nucleotide Metabolic Process Purine Nucleoside Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Mitochondrial ATP Synthesis Coupled Electron Transport Maintenance Of Blood-brain Barrier Meiotic Metaphase I Plate Congression Meiotic Spindle Midzone Assembly Ribonucleotide Metabolic Process Nucleoside Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Oxidative Phosphorylation RNA Export From Nucleus Negative Regulation Of Mitotic Recombination ER-associated Misfolded Protein Catabolic Process Positive Regulation Of Fibroblast Growth Factor Production Generation Of Precursor Metabolites And Energy Female Gamete Generation Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Negative Regulation Of Synaptic Transmission, Dopaminergic Nicotinamide Metabolic Process Positive Regulation Of Platelet-derived Growth Factor Production Nuclear Export MRNA Transport Posttranscriptional Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Organophosphate Metabolic Process RNA Transport Positive Regulation Of Brown Fat Cell Differentiation Nuclear-transcribed MRNA Catabolic Process RNA Localization Heterocycle Metabolic Process MRNA Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Brown Fat Cell Differentiation Positive Regulation Of Prostaglandin Biosynthetic Process MRNA Catabolic Process Positive Regulation Of Synaptic Plasticity Spindle Midzone Assembly Positive Regulation Of Sprouting Angiogenesis Cellular Nitrogen Compound Metabolic Process RNA Catabolic Process
Tagcloud ?		adapt autoadaptive built cleared clients deploys dislocation dislocon dislocons engage erad folding herp hrd1 interrupt ligases machineries misfolded p97 perturbation polyubiquitylation preempt proteasomal proteostasis relay relies tuning turnover ubc6e	15d abpp bat5 c14 c18 c20 c7600 dag delta12 diacylglycerol ebelactone genuine glycerolipid hbat5 j2 linoleylglycerol lysophospholipase mag mags monoacylglycerols oxadiazol palmostatin pave pgj2 phenoxyphenyl tetrahydrolipstatin triacylglycerol unveiling
Tagcloud (Difference) ?		adapt autoadaptive built cleared clients deploys dislocation dislocon dislocons engage erad folding herp hrd1 interrupt ligases machineries misfolded p97 perturbation polyubiquitylation preempt proteasomal proteostasis relay relies tuning turnover ubc6e	15d abpp bat5 c14 c18 c20 c7600 dag delta12 diacylglycerol ebelactone genuine glycerolipid hbat5 j2 linoleylglycerol lysophospholipase mag mags monoacylglycerols oxadiazol palmostatin pave pgj2 phenoxyphenyl tetrahydrolipstatin triacylglycerol unveiling
Tagcloud (Intersection) ?