RGS10 and GNRHR

Number of citations of the paper that reports this interaction (PMID 12062898)
3

Data Source:
HPRD (in vivo)

		RGS10	GNRHR
Gene Name		regulator of G-protein signaling 10	gonadotropin-releasing hormone receptor
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Neuronal Cell Body Dendritic Spine Axon Terminus	Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	GTPase Activator Activity	Gonadotropin-releasing Hormone Receptor Activity Peptide Binding
	Biological Process	Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity	G-protein Coupled Receptor Signaling Pathway Multicellular Organismal Development Cellular Response To Gonadotropin-releasing Hormone
Pathways		Signaling by GPCR GPCR downstream signaling G alpha (i) signalling events	G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Hormone ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs			Leuprolide Goserelin Cetrorelix Abarelix Gonadorelin Nafarelin Danazol Degarelix Buserelin
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ADRB2 APP CALM1 GNAI1 GNAI3 GNAO1 GNAZ GNRHR PRKACA	2 interactors: GNRH1 RGS10
Entrez ID		6001	2798
HPRD ID		04172	00732
Ensembl ID		ENSG00000148908
Uniprot IDs		O43665	P30968
PDB IDs		2DLR 2I59 2IHB
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Regulation Of Adenylate Cyclase Activity Platelet Activation Regulation Of Cyclase Activity Cell Surface Receptor Signaling Pathway Regulation Of CAMP Biosynthetic Process Regulation Of CAMP Metabolic Process Activation Of Adenylate Cyclase Activity Blood Coagulation Hemostasis Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Lyase Activity Regulation Of Body Fluid Levels Wound Healing Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Positive Regulation Of CAMP Biosynthetic Process Signal Transduction Positive Regulation Of CAMP Metabolic Process Cell Activation Response To Wounding Signaling Cell Communication Positive Regulation Of Cyclic Nucleotide Metabolic Process Response To Organonitrogen Compound Cellular Response To Stimulus Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Protein Binding Regulation Of Muscle Contraction Regulation Of Heart Contraction Negative Regulation Of Adenylate Cyclase Activity Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Lyase Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Response To Stress Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Calcium Ion Transport Synaptic Transmission Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of CAMP Biosynthetic Process Regulation Of Ion Transport Rhodopsin Mediated Signaling Pathway Negative Regulation Of CAMP Metabolic Process Regulation Of Catalytic Activity Response To Stimulus Vesicle-mediated Transport Regulation Of Phosphorus Metabolic Process Negative Regulation Of Nucleotide Metabolic Process	Regulation Of Ovarian Follicle Development Regulation Of Female Gonad Development
Tagcloud ?		alveolar avenues bones combat craniofacial destruction forearm isoflavone menopausal microbe mkp multipotent nfatc1 oscillation oscillations osteoclast osteoclastogenesis periodontal periodontitis periosteum relate resorption rgs12 soy sscs supplementation supplements tolerability unsatisfactory	aas aass abused anabolic androgenic arr19 cyp11a1 cyp17a1 dax1 disturbed enanthate hsd17b4 hsd3b1 hsd3b5 insl3 intramuscular leydig lhcgr milieu oppositely prka prlr1 prlr2 prolactin star steroidogenesis steroidogenic testosterone tspo
Tagcloud (Difference) ?		alveolar avenues bones combat craniofacial destruction forearm isoflavone menopausal microbe mkp multipotent nfatc1 oscillation oscillations osteoclast osteoclastogenesis periodontal periodontitis periosteum relate resorption rgs12 soy sscs supplementation supplements tolerability unsatisfactory	aas aass abused anabolic androgenic arr19 cyp11a1 cyp17a1 dax1 disturbed enanthate hsd17b4 hsd3b1 hsd3b5 insl3 intramuscular leydig lhcgr milieu oppositely prka prlr1 prlr2 prolactin star steroidogenesis steroidogenic testosterone tspo
Tagcloud (Intersection) ?