RGS2 and METTL18

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		RGS2	METTL18
Gene Name		regulator of G-protein signaling 2	methyltransferase like 18
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleolus Cytoplasm Mitochondrion Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Neuron Projection	Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding Calmodulin Binding Beta-tubulin Binding	Protein Methyltransferase Activity
	Biological Process	Regulation Of Translation Cell Cycle Spermatogenesis Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Phospholipase Activity Negative Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Microtubule Polymerization Termination Of G-protein Coupled Receptor Signaling Pathway Negative Regulation Of MAP Kinase Activity Positive Regulation Of GTPase Activity Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Brown Fat Cell Differentiation Relaxation Of Cardiac Muscle Relaxation Of Vascular Smooth Muscle Positive Regulation Of Cardiac Muscle Contraction Regulation Of Adrenergic Receptor Signaling Pathway	Protein Methylation
Pathways		G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK
Drugs
Diseases
GWAS
Protein-Protein Interactions		58 interactors: ADCY5 ADRA1A ADRB2 ARFGAP1 BBS10 CALM1 CHD3 CLTA COMT COPB1 COPB2 CRMP1 CTSB DDR1 DUSP21 DYNLL1 EIF3L FZD5 GDE1 GIT1 GNA15 GNAI3 GNAQ GNAS HAUS5 HSPA8 IER3IP1 KIAA1377 KLK8 LIG1 LRFN1 METTL18 MON1A MTUS2 NINL NIPSNAP1 PARK2 PPP1R9B PRKCA PRKCB PRKCG PRKCSH PRKG1 RAB2A RABAC1 RAP1B REEP5 RIN3 SCN5A TSPAN15 TUBB2B UBC VPS29 WDR74 XRCC6 ZBTB48 ZNF579 ZYX	4 interactors: B3GALT4 PHYHIP RGS2 YAE1D1
Entrez ID		5997	92342
HPRD ID		02917	14713
Ensembl ID		ENSG00000116741	ENSG00000171806
Uniprot IDs		P41220	O95568
PDB IDs		2AF0 2V4Z 4EKC 4EKD
Enriched GO Terms of Interacting Partners?		Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Positive Regulation Of Phospholipase Activity Platelet Activation Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity Regulation Of Catalytic Activity Regulation Of Body Fluid Levels Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Response To Wounding Blood Coagulation G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Hemostasis Wound Healing Cell-cell Signaling Regulation Of Phosphorus Metabolic Process Regulation Of Adenylate Cyclase Activity Nervous System Development Regulation Of Cyclase Activity Activation Of Adenylate Cyclase Activity Signaling Response To Stress Neurotrophin Signaling Pathway Cell Communication Regulation Of Phosphorylation Dopamine Receptor Signaling Pathway Positive Regulation Of Catalytic Activity Developmental Process Positive Regulation Of Adenylate Cyclase Activity Regulation Of Kinase Activity Response To Organic Substance Cellular Response To Stimulus Regulation Of Muscle Contraction Anatomical Structure Development Regulation Of CAMP Biosynthetic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Positive Regulation Of Hydrolase Activity Cell Activation Membrane Organization Regulation Of CAMP Metabolic Process Regulation Of Protein Phosphorylation System Development Positive Regulation Of Lyase Activity Enzyme Linked Receptor Protein Signaling Pathway Golgi Vesicle Budding Adrenergic Receptor Signaling Pathway	Regulation Of Adrenergic Receptor Signaling Pathway Positive Regulation Of Cardiac Muscle Contraction Negative Regulation Of CAMP-mediated Signaling Negative Regulation Of Phospholipase Activity Relaxation Of Vascular Smooth Muscle Negative Regulation Of Cardiac Muscle Hypertrophy Relaxation Of Smooth Muscle Negative Regulation Of Muscle Hypertrophy Positive Regulation Of Striated Muscle Contraction Relaxation Of Cardiac Muscle Positive Regulation Of Microtubule Polymerization Negative Regulation Of Smooth Muscle Contraction Negative Regulation Of Lipase Activity Negative Regulation Of Muscle Contraction Regulation Of CAMP-mediated Signaling Relaxation Of Muscle Positive Regulation Of Heart Contraction Regulation Of Microtubule Polymerization Regulation Of Cardiac Muscle Hypertrophy Vasodilation Brown Fat Cell Differentiation Regulation Of Smooth Muscle Contraction Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Blood Vessel Size Regulation Of Tube Size Regulation Of Cardiac Muscle Contraction Negative Regulation Of MAP Kinase Activity Regulation Of Phospholipase Activity Regulation Of Striated Muscle Contraction Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Protein Polymerization Fat Cell Differentiation Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Microtubule Cytoskeleton Organization Regulation Of Muscle Contraction Negative Regulation Of MAPK Cascade Regulation Of Heart Contraction Regulation Of Microtubule-based Process Positive Regulation Of Protein Complex Assembly Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Tagcloud ?		3t3 adipocyte already arrested beginning cloned clones differentially earliest ebpalpha hif hsp105 inducers l1 master mrnas nih nineteen place ppargamma2 preadipocyte proliferating regulators rho seemed steps takes tc10 vdr
Tagcloud (Difference) ?		3t3 adipocyte already arrested beginning cloned clones differentially earliest ebpalpha hif hsp105 inducers l1 master mrnas nih nineteen place ppargamma2 preadipocyte proliferating regulators rho seemed steps takes tc10 vdr
Tagcloud (Intersection) ?