RCVRN and GIT2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RCVRN	GIT2
Gene Name		recoverin	G protein-coupled receptor kinase interacting ArfGAP 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Dendrite	Nucleoplasm Focal Adhesion
	Molecular Function	Calcium Ion Binding Calcium Sensitive Guanylate Cyclase Activator Activity	Protein Binding ARF GTPase Activator Activity Zinc Ion Binding
	Biological Process	Signal Transduction Visual Perception Phototransduction, Visible Light Rhodopsin Mediated Signaling Pathway Regulation Of Rhodopsin Mediated Signaling Pathway Positive Regulation Of Guanylate Cyclase Activity Regulation Of Calcium Ion Transport	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of ARF GTPase Activity Positive Regulation Of GTPase Activity Behavioral Response To Pain
Pathways		Inactivation, recovery and regulation of the phototransduction cascade Visual phototransduction The phototransduction cascade Diseases associated with visual transduction
Drugs
Diseases
GWAS			Metabolic syndrome ( 20694148) Metabolite levels (MHPG) ( 23319000)
Protein-Protein Interactions		11 interactors: ADRBK1 CAV1 GIT2 GRK1 GRK5 GRK6 IL15RA PQBP1 SMAD3 TGFBR2 TOP1	44 interactors: ACTG1 ACTN1 ADRBK1 ARHGEF7 ATF5 C4BPA CALCOCO2 CORO1A E2F2 EDC4 GCH1 GIT1 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG
Entrez ID		5957	9815
HPRD ID		01558	09779
Ensembl ID			ENSG00000139436
Uniprot IDs		P35243 Q53XL0	F8VXI9 Q14161 Q6FI58
PDB IDs		2D8N
Enriched GO Terms of Interacting Partners?		Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Signal Transduction Phosphorylation Regulation Of The Force Of Heart Contraction By Chemical Signal Tachykinin Receptor Signaling Pathway Regulation Of Signaling Cell Surface Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Wound Healing Programmed Cell Death Cell Death Death Phosphate-containing Compound Metabolic Process Regulation Of The Force Of Heart Contraction Receptor Internalization Response To Stimulus Protein Phosphorylation Peptidyl-threonine Phosphorylation Wnt Signaling Pathway Positive Regulation Of Catalytic Activity Embryonic Cranial Skeleton Morphogenesis Signal Transduction Cardiovascular System Development Regulation Of Membrane Repolarization During Action Potential Positive Regulation Of Transforming Growth Factor Beta3 Production Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Tolerance Induction To Self Antigen Negative Regulation Of The Force Of Heart Contraction By Chemical Signal Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Receptor-mediated Endocytosis Enzyme Linked Receptor Protein Signaling Pathway Camera-type Eye Development Positive Regulation Of Cell Adhesion Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Receptor Metabolic Process Mammary Gland Morphogenesis Eye Development Apoptotic Process Regulation Of Striated Muscle Contraction Negative Regulation Of Cell Death Signaling Organ Morphogenesis Lens Development In Camera-type Eye Positive Regulation Of Hydrolase Activity	Regulation Of Apoptotic Process Regulation Of Cell Death Ephrin Receptor Signaling Pathway Innate Immune Response Response To External Stimulus Enzyme Linked Receptor Protein Signaling Pathway Response To Stimulus Apoptotic Process Regulation Of Signaling Programmed Cell Death Regulation Of Signal Transduction Immune System Process Immune Response Regulation Of Immune System Process Cell Death Regulation Of Metabolic Process Death Positive Regulation Of Immune Response Defense Response Signal Transduction Regulation Of Immune Response Immune Response-regulating Signaling Pathway Adherens Junction Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Immune System Process Focal Adhesion Assembly Positive Regulation Of Metabolic Process Regulation Of Catalytic Activity Regulation Of Phosphorus Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell-cell Junction Organization Regulation Of Protein Kinase Activity Positive Regulation Of Catalytic Activity Signaling Regulation Of Kinase Activity Cellular Component Assembly Cell Communication Regulation Of Phosphorylation Adherens Junction Assembly Regulation Of Protein Phosphorylation Regulation Of Cellular Component Organization Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Cell Development Cell-substrate Junction Assembly Activation Of MAPK Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Response To Stress Activation Of Innate Immune Response Cell Surface Receptor Signaling Pathway
Tagcloud ?			ancient autophosphorylation coordinates deregulated dimerization exchange gef git1 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Difference) ?			ancient autophosphorylation coordinates deregulated dimerization exchange gef git1 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Intersection) ?