RBBP7 and NR2E3

Number of citations of the paper that reports this interaction (PMID 17255935)
27

Data Source:
HPRD (in vivo)

		RBBP7	NR2E3
Gene Name		retinoblastoma binding protein 7	nuclear receptor subfamily 2, group E, member 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm NuRD Complex ESC/E(Z) Complex	Nucleus Nucleoplasm Transcription Factor Complex
	Molecular Function	RNA Binding Protein Binding	Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Replication Chromatin Organization Nucleosome Assembly Transcription, DNA-templated Multicellular Organismal Development Cell Proliferation Gene Expression Negative Regulation Of Cell Growth CENP-A Containing Nucleosome Assembly Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Cellular Heat Acclimation	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Signal Transduction Visual Perception Phototransduction Negative Regulation Of Cell Proliferation Gene Expression Intracellular Receptor Signaling Pathway Eye Photoreceptor Cell Development Steroid Hormone Mediated Signaling Pathway Positive Regulation Of Rhodopsin Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Retina Development In Camera-type Eye
Pathways		Chromosome Maintenance HDACs deacetylate histones Chromatin organization RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Promoter Clearance Deposition of new CENPA-containing nucleosomes at the centromere Epigenetic regulation of gene expression Cellular Senescence HATs acetylate histones PRC2 methylates histones and DNA RMTs methylate histone arginines Chromatin modifying enzymes Nucleosome assembly Oxidative Stress Induced Senescence
Drugs
Diseases
GWAS			Metabolite levels (HVA/MHPG ratio) ( 23319000)
Protein-Protein Interactions		28 interactors: APPL1 APPL2 BCL11B BRCA1 BRMS1 BRMS1L CHD4 CREBBP DHX30 ESR1 GATAD2B HDAC1 HDAC2 HIST3H3 ING1 LINC00152 MBD3 MBD3L2 MTA2 NR2E3 RB1 RBBP4 RBP1 SALL2 SAP30 SIN3A SUV39H1 TWIST1	27 interactors: BCL11A CDK9 CRX DEDD2 DHX30 ELAVL2 HDAC1 HDAC3 HOXC13 IRF9 MYBBP1A NCOR1 NR1D1 NR3C1 POLR3D PPARG RARA RBBP4 RBBP7 RBFOX2 RBL1 RXRA RXRB SIN3A SNAPC1 TBL3 ZNF232
Entrez ID		5931	10002
HPRD ID		04231	05132
Ensembl ID		ENSG00000102054
Uniprot IDs		E9PC52 Q16576 Q6FHQ0	B6ZGU0 F1D8Q9 Q9Y5X4
PDB IDs		3CFS 3CFV
Enriched GO Terms of Interacting Partners?		Chromatin Organization Chromatin Modification Chromosome Organization Negative Regulation Of Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression, Epigenetic Transcription, DNA-templated Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Chromatin Remodeling Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process ATP-dependent Chromatin Remodeling Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Cellular Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Histone Modification Regulation Of Gene Expression Organelle Organization Macromolecule Biosynthetic Process Histone Deacetylation Protein Deacetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Rhythmic Process Histone H3-K9 Modification Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Eyelid Development In Camera-type Eye Tissue Development Negative Regulation Of Histone Acetylation	RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA-templated Transcription, Initiation Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Steroid Hormone Mediated Signaling Pathway Intracellular Receptor Signaling Pathway Cellular Metabolic Process Hormone-mediated Signaling Pathway Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Circadian Regulation Of Gene Expression Circadian Rhythm Rhythmic Process Cellular Response To Steroid Hormone Stimulus Chromatin Modification Positive Regulation Of Metabolic Process Chromatin Organization Regulation Of Receptor Biosynthetic Process Response To Organic Substance
Tagcloud ?		accessibility acetyltransferase alanine applicable bait code govern h3s10 hat1 mimic nonhydrolyzable outlined partners phosphonomethylen pma posttranslational ptms pull recruit retinoblastoma s10 scheme silac studying tail tails threonine uncovered unmodified	11a causing compound correlates cytotoxic cytotoxicity eralpha excluding facilitate favorable hct116 hela implying isogenic mediator mutated nci null orphan p53 photoreceptor pleiotropic pnr responsive retain retinal systematic tamoxifen varying
Tagcloud (Difference) ?		accessibility acetyltransferase alanine applicable bait code govern h3s10 hat1 mimic nonhydrolyzable outlined partners phosphonomethylen pma posttranslational ptms pull recruit retinoblastoma s10 scheme silac studying tail tails threonine uncovered unmodified	11a causing compound correlates cytotoxic cytotoxicity eralpha excluding facilitate favorable hct116 hela implying isogenic mediator mutated nci null orphan p53 photoreceptor pleiotropic pnr responsive retain retinal systematic tamoxifen varying
Tagcloud (Intersection) ?