RAD51 and RAD54B

Number of citations of the paper that reports this interaction (PMID 10851248)
15

Data Source:
HPRD (in vivo)

		RAD51	RAD54B
Gene Name		RAD51 recombinase	RAD54 homolog B (S. cerevisiae)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromosome Condensed Chromosome Condensed Nuclear Chromosome Lateral Element Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Mitochondrial Matrix Microtubule Organizing Center PML Body Perinuclear Region Of Cytoplasm	Nucleus
	Molecular Function	Damaged DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Protein Binding ATP Binding Protein C-terminus Binding Identical Protein Binding Single-stranded DNA-dependent ATPase Activity DNA Polymerase Binding	DNA Binding DNA Helicase Activity RNA Helicase Activity ATP Binding DNA Translocase Activity
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Recombinase Assembly DNA Unwinding Involved In DNA Replication DNA Repair Double-strand Break Repair DNA Recombination Mitotic Recombination Cellular Response To DNA Damage Stimulus Meiotic Nuclear Division Reciprocal Meiotic Recombination Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of DNA Ligation Protein Homooligomerization Cellular Response To Ionizing Radiation Cellular Response To Camptothecin	Double-strand Break Repair Via Homologous Recombination Mitotic Recombination Reciprocal Meiotic Recombination DNA Duplex Unwinding
Pathways		Assembly of the RAD51-ssDNA nucleoprotein complex Homologous DNA pairing and strand exchange Meiotic recombination Homologous Recombination Repair Homologous recombination repair of replication-independent double-strand breaks Double-Strand Break Repair Presynaptic phase of homologous DNA pairing and strand exchange
Drugs
Diseases
GWAS
Protein-Protein Interactions		42 interactors: ABL1 ATM ATRX BCCIP BLM BRCA1 BRCA2 CASP3 CASP7 CHD3 CHEK1 DMC1 DNAJA3 ERCC2 FANCD2 FBXO18 HID1 HNRNPC IRS1 MDC1 NXF1 PFN1 RAD18 RAD51AP1 RAD51AP2 RAD51C RAD52 RAD54B RAD54L RPA1 RPA3 SFR1 SUMO1 SWI5 SWSAP1 TP53 UBE2I UGDH UHRF2 VIM WRN ZDHHC17	26 interactors: ANKRD36BP1 ATPAF2 CCDC33 CDC23 CSNK1E DMC1 DYRK2 ENKD1 GMCL1 GORASP2 LNX1 MDM4 MYO15B NIF3L1 NUDT18 PRKAA1 PSMA1 RAD51 RIBC2 SUMO1 TCEANC TCEB3 TRAPPC6A UBE2I WRN ZNF580
Entrez ID		5888	25788
HPRD ID		01557	05049
Ensembl ID		ENSG00000051180	ENSG00000197275
Uniprot IDs		Q06609	O95073 Q9Y620
PDB IDs		1B22 1N0W
Enriched GO Terms of Interacting Partners?		DNA Metabolic Process DNA Repair Cellular Response To DNA Damage Stimulus Double-strand Break Repair Via Homologous Recombination Recombinational Repair Double-strand Break Repair DNA Recombination Cellular Response To Stress Response To Stress Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Response To Radiation Cellular Nitrogen Compound Metabolic Process Chromosome Organization Response To Ionizing Radiation Organelle Organization Cell Cycle Nitrogen Compound Metabolic Process Cellular Response To Stimulus DNA Duplex Unwinding DNA Geometric Change Response To Abiotic Stimulus Regulation Of Cell Cycle Response To Stimulus Cell Cycle Process DNA-dependent DNA Replication DNA Replication Signal Transduction In Response To DNA Damage Meiotic Nuclear Division Cellular Response To Ionizing Radiation DNA Conformation Change Positive Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Cell Aging Response To UV Meiotic Cell Cycle Cellular Response To Radiation DNA Catabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Cell Cycle Process Cellular Metabolic Process Replication Fork Processing Cellular Response To Hydroxyurea Intrinsic Apoptotic Signaling Pathway Meiosis I Response To Gamma Radiation Signal Transduction By P53 Class Mediator DNA Recombinase Assembly Regulation Of Response To DNA Damage Stimulus	Cell Cycle Cell Cycle Process Cellular Response To Stress Response To Camptothecin Cellular Response To DNA Damage Stimulus Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Metabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Proteolysis Signal Transduction By P53 Class Mediator Protein Modification By Small Protein Conjugation Positive Regulation Of Cellular Metabolic Process Protein Sumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Response To Ionizing Radiation Regulation Of Metabolic Process Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Proteasomal Protein Catabolic Process Reciprocal Meiotic Recombination Ubiquitin-dependent Protein Catabolic Process DGDP Catabolic Process DADP Catabolic Process GDP Catabolic Process Response To Brefeldin A Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Positive Regulation Of SUMO Transferase Activity Modification-dependent Protein Catabolic Process Organelle Organization Response To Gamma Radiation Chromosome Segregation Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Recombination Nitrogen Compound Metabolic Process Cellular Response To Ionizing Radiation Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Proteolysis Involved In Cellular Protein Catabolic Process Peptidyl-amino Acid Modification Cellular Response To Hydrogen Peroxide Heterocycle Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transferase Activity Cellular Protein Catabolic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Proteasomal Protein Catabolic Process
Tagcloud ?		boundary box cerevisiae consisting damaging declined delta dosage dsc1 elements enhances fluctuate fluctuation frequency mbf1 mbp1 mcb meiosis meiotic mitotic mlu rad54 recombination saccharomyces spore sporulation swi6 transcript viability	behind checkpoint checkpoints constitutive critically ddr downregulated dynamically facilitating fate fine g2 helicase influences instability integrity ligase limiting limits maintaining mdm2 mdmx override phases scaffold scaffolding snf2 strength tuning
Tagcloud (Difference) ?		boundary box cerevisiae consisting damaging declined delta dosage dsc1 elements enhances fluctuate fluctuation frequency mbf1 mbp1 mcb meiosis meiotic mitotic mlu rad54 recombination saccharomyces spore sporulation swi6 transcript viability	behind checkpoint checkpoints constitutive critically ddr downregulated dynamically facilitating fate fine g2 helicase influences instability integrity ligase limiting limits maintaining mdm2 mdmx override phases scaffold scaffolding snf2 strength tuning
Tagcloud (Intersection) ?