RAB5C and RABAC1

Number of citations of the paper that reports this interaction (PMID 10329441)
15

Data Source:
HPRD (two hybrid, in vitro)

		RAB5C	RABAC1
Gene Name		RAB5C, member RAS oncogene family	Rab acceptor 1 (prenylated)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Early Endosome Lipid Particle Plasma Membrane Endocytic Vesicle Early Endosome Membrane Melanosome Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome	Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Integral Component Of Membrane Cell Junction
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding	Protein Binding Protein C-terminus Binding Identical Protein Binding Proline-rich Region Binding
	Biological Process	Intracellular Protein Transport Regulation Of Endocytosis Rab Protein Signal Transduction Plasma Membrane To Endosome Transport
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: APP APPL2 EEA1 RABAC1 RBSN RIN2 RIN3 SGSM3 TBC1D15 TBC1D17	63 interactors: ADCK3 CMTM3 CREB3 DUSP12 FAM160A2 FXR2 GDI1 HRAS HRG LNX1 MAD2L1 MCF2L MIEF2 NAT14 NDRG4 NIF3L1 NR3C2 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP5 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RPS20 RRAS2 SGK1 SNCA SNX1 SNX10 SNX11 SNX15 SPG21 SYT16 TNIP1 TRIM32 TSHR TUBB2A TXN2 VAMP2 VIM VTA1 WDYHV1 WIPI2 ZFYVE21
Entrez ID		5878	10567
HPRD ID		04947	05375
Ensembl ID		ENSG00000108774	ENSG00000105404
Uniprot IDs		P51148	Q9UI14
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Positive Regulation Of Ras GTPase Activity Positive Regulation Of Hydrolase Activity Regulation Of Ras GTPase Activity Regulation Of Catalytic Activity Regulation Of Ras Protein Signal Transduction Vesicle-mediated Transport Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Positive Regulation Of Catalytic Activity Regulation Of GTPase Activity Regulation Of Signal Transduction Regulation Of Signaling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Endosomal Transport Endocytosis Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Regulation Of Intracellular Signal Transduction Mating Regulation Of Protein Tyrosine Kinase Activity Positive Regulation Of Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Regulation Of ERBB Signaling Pathway Synaptic Vesicle To Endosome Fusion Feeding Behavior Cholesterol Metabolic Process Synaptic Growth At Neuromuscular Junction Regulation Of Receptor Activity Sterol Metabolic Process Neuromuscular Process Intracellular Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Binding Transition Metal Ion Homeostasis Transport Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Peptidyl-tyrosine Phosphorylation Axon Choice Point Recognition Plasma Membrane To Endosome Transport Locomotory Behavior Establishment Of Localization In Cell	Ras Protein Signal Transduction Rab Protein Signal Transduction Small GTPase Mediated Signal Transduction Establishment Of Protein Localization Protein Transport Protein Localization Cellular Protein Localization Cellular Localization Intracellular Protein Transport Regulation Of Cellular Component Organization Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport Establishment Of Localization In Cell Intracellular Transport Intracellular Signal Transduction Endosomal Transport Regulation Of Exocytosis Transport Cellular Response To Stimulus Cell Communication Regulation Of Endocytosis Endocytosis Regulation Of Locomotion Vesicle Organization Endosome Organization Response To Stimulus Regulation Of Synaptic Vesicle Transport Regulation Of Cell Projection Organization Signaling Signal Transduction Cytoplasmic Transport Establishment Of Vesicle Localization Regulation Of Neuronal Synaptic Plasticity Vesicle Localization Regulation Of Organelle Organization Regulation Of Cell Migration Positive Regulation Of Metabolic Process Early Endosome To Late Endosome Transport Regulation Of Neurotransmitter Secretion Regulation Of Cell Motility Regulation Of Signaling Regulation Of Cellular Localization Regulation Of Cellular Component Movement Regulation Of Cellular Process Regulation Of Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Transport Synaptic Vesicle Recycling Endomembrane System Organization
Tagcloud ?		cdc42 compartment coordinately cytomegalovirus ectopic encode golgi hcmv herpesviruses infectious micrornas mirna mirnas mirs morphogenesis noninfectious rab11a reorganization resemble secretory sirnas snap23 stacks ul112 uncovered us5 vac vamp3 virion
Tagcloud (Difference) ?		cdc42 compartment coordinately cytomegalovirus ectopic encode golgi hcmv herpesviruses infectious micrornas mirna mirnas mirs morphogenesis noninfectious rab11a reorganization resemble secretory sirnas snap23 stacks ul112 uncovered us5 vac vamp3 virion
Tagcloud (Intersection) ?