RRAGD and CHST15

Number of citations of the paper that reports this interaction (PMID 11073942)
44

Data Source:
HPRD (in vivo)

		RRAGD	CHST15
Gene Name		Ras-related GTP binding D	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Lysosome EGO Complex Gtr1-Gtr2 GTPase Complex	Golgi Membrane Integral Component Of Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Protein Heterodimerization Activity	3'-phosphoadenosine 5'-phosphosulfate Binding N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase Activity
	Biological Process	Cellular Response To Starvation Regulation Of Autophagy Positive Regulation Of TOR Signaling Cellular Protein Localization Cellular Response To Amino Acid Stimulus	Carbohydrate Metabolic Process Pathogenesis Hexose Biosynthetic Process Glycosaminoglycan Metabolic Process Chondroitin Sulfate Metabolic Process Chondroitin Sulfate Biosynthetic Process Small Molecule Metabolic Process
Pathways			MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Chondroitin sulfate/dermatan sulfate metabolism Defective SLC26A2 causes chondrodysplasias Glycosaminoglycan metabolism Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective CHST14 causes EDS, musculocontractural type Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Defective CHST6 causes MCDC1 Glycogen storage diseases MPS IIID - Sanfilippo syndrome D Chondroitin sulfate biosynthesis MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A Defective CHSY1 causes TPBS MPS IV - Morquio syndrome B MPS VII - Sly syndrome Metabolism of carbohydrates MPS VI - Maroteaux-Lamy syndrome
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CHST15 MTOR NOL8 RRAGA RRAGB	3 interactors: HCK LYN RRAGD
Entrez ID		58528	51363
HPRD ID		12199	12203
Ensembl ID		ENSG00000025039	ENSG00000182022
Uniprot IDs		Q9NQL2	B4DH74 Q7LFX5
PDB IDs		2Q3F
Enriched GO Terms of Interacting Partners?		Regulation Of Autophagy Response To Amino Acid Cellular Response To Nutrient Levels Cellular Response To Extracellular Stimulus Positive Regulation Of TOR Signaling Response To Nutrient Levels Regulation Of TOR Signaling Cellular Response To Amino Acid Stimulus Response To Extracellular Stimulus Cellular Response To Organonitrogen Compound Regulation Of Carbohydrate Utilization Cellular Response To Starvation Positive Regulation Of Intracellular Signal Transduction Response To Organonitrogen Compound Cellular Response To Acid Chemical Response To Starvation Positive Regulation Of Cytolysis Positive Regulation Of Signal Transduction Negative Regulation Of NFAT Protein Import Into Nucleus Positive Regulation Of Transcription From RNA Polymerase III Promoter Cellular Response To Stress Negative Regulation Of Macroautophagy Positive Regulation Of Lamellipodium Assembly Negative Regulation Of Cell Size Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Lamellipodium Organization Regulation Of Intracellular Signal Transduction Regulation Of Response To Food Response To External Stimulus Cellular Response To Organic Substance Regulation Of Rac GTPase Activity TOR Signaling Regulation Of Transcription From RNA Polymerase III Promoter Chondroitin Sulfate Biosynthetic Process Modulation By Virus Of Host Morphology Or Physiology Regulation Of Lamellipodium Assembly Chondroitin Sulfate Proteoglycan Biosynthetic Process Regulation Of Cellular Response To Heat Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Oxidation Positive Regulation Of Myotube Differentiation Negative Regulation Of Autophagy Regulation Of Rac Protein Signal Transduction Ruffle Organization Regulation Of Glycogen Metabolic Process Positive Regulation Of Stress Fiber Assembly Peptidyl-threonine Phosphorylation Positive Regulation Of Actin Filament Bundle Assembly Negative Regulation Of Transcription Factor Import Into Nucleus Response To Organic Substance	Peptidyl-tyrosine Autophosphorylation Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Organonitrogen Compound Leukocyte Degranulation Regulated Secretory Pathway Response To Organonitrogen Compound Response To Amino Acid Positive Regulation Of Oligodendrocyte Progenitor Proliferation Respiratory Burst After Phagocytosis Negative Regulation Of Mast Cell Proliferation Cellular Response To Lipopolysaccharide Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To Molecule Of Bacterial Origin Cellular Response To Acid Chemical Protein Autophosphorylation Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Leukocyte Migration Involved In Immune Response Cellular Response To Extracellular Stimulus Leukocyte Migration Tolerance Induction To Self Antigen Fc Receptor Mediated Inhibitory Signaling Pathway Positive Regulation Of Dendritic Cell Apoptotic Process Phagocytosis Fc Receptor Signaling Pathway Regulation Of Inflammatory Response Immune Response-activating Cell Surface Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Response To External Stimulus Cellular Response To Organic Substance Cellular Response To Peptide Hormone Stimulus Response To Lipopolysaccharide Cellular Response To Peptide Negative Regulation Of Toll-like Receptor 2 Signaling Pathway Immune Response-inhibiting Cell Surface Receptor Signaling Pathway Respiratory Burst Involved In Defense Response Response To Molecule Of Bacterial Origin Exocytosis Immune Response-inhibiting Signal Transduction Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Vesicle-mediated Transport Regulation Of Podosome Assembly Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Tolerance Induction Positive Regulation Of Mast Cell Proliferation Cellular Response To Lipid Inflammatory Response Positive Regulation Of B Cell Receptor Signaling Pathway Cellular Localization
Tagcloud ?		0e 1426a 219g 3072g abhd16a abhd5 acp2 alms1 apoa2 atp1a2 bft col14a1 ctsf dars decr1 ghrl intron3 mc4r mttp nfkbia nt5e pfp plat ppp2r5d rfc2 sdhd serpinf1 tbc1d1 ube2h
Tagcloud (Difference) ?		0e 1426a 219g 3072g abhd16a abhd5 acp2 alms1 apoa2 atp1a2 bft col14a1 ctsf dars decr1 ghrl intron3 mc4r mttp nfkbia nt5e pfp plat ppp2r5d rfc2 sdhd serpinf1 tbc1d1 ube2h
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