MID1IP1 and MID1

Number of citations of the paper that reports this interaction (PMID 15070402)
14

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		MID1IP1	MID1
Gene Name		MID1 interacting protein 1	midline 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Microtubule Microtubule Cytoskeleton	Spindle Cytosol Microtubule Microtubule Associated Complex Cytoplasmic Microtubule
	Molecular Function	Protein C-terminus Binding	Microtubule Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Protein Heterodimerization Activity Phosphoprotein Binding
	Biological Process	Lipid Metabolic Process Negative Regulation Of Microtubule Depolymerization Positive Regulation Of Fatty Acid Biosynthetic Process Regulation Of Lipid Biosynthetic Process Protein Polymerization Positive Regulation Of Ligase Activity	Microtubule Cytoskeleton Organization Negative Regulation Of Microtubule Depolymerization Pattern Specification Process Metabolic Process Cytokine-mediated Signaling Pathway Positive Regulation Of Stress-activated MAPK Cascade Protein Localization To Microtubule Interferon-gamma-mediated Signaling Pathway
Pathways			Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: AK8 APOE GSK3B MID1 MID2 SUFU	30 interactors: BYSL DYRK4 EHHADH FKBP1A GMCL1 HTT IGBP1 MEOX1 MID1IP1 MID2 OTUB2 PKN1 PPP2CA PPP2CB PPP2R4 STK36 TCEANC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2N UBE2V1 UBE2W UBTD1
Entrez ID		58526	4281
HPRD ID		06732	02047
Ensembl ID		ENSG00000165175	ENSG00000101871
Uniprot IDs		Q9NPA3	O15344
PDB IDs			2DQ5 2FFW 2JUN
Enriched GO Terms of Interacting Partners?		Protein Localization To Microtubule Protein Localization To Cytoskeleton Cellular Protein Localization Negative Regulation Of Dendrite Development Protein Localization Positive Regulation Of Axon Extension Central Nervous System Development Cellular Localization Negative Regulation Of Transcription Factor Import Into Nucleus Regulation Of Neuronal Synaptic Plasticity Regulation Of Protein Catabolic Process Negative Regulation Of Transport Regulation Of Signal Transduction Regulation Of Axon Extension Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Biosynthetic Process Positive Regulation Of Axonogenesis Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of MAP Kinase Activity Protein Localization To Organelle Negative Regulation Of Intracellular Protein Transport Regulation Of Signaling Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Positive Regulation Of Dendritic Spine Maintenance Negative Regulation Of Dendritic Spine Maintenance Negative Regulation Of Phospholipid Efflux Negative Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Lipid Transport Across Blood Brain Barrier Positive Regulation Of Postsynaptic Membrane Organization Negative Regulation Of Postsynaptic Membrane Organization Cellular Response To Cytokine Stimulus Regulation Of Dendrite Development Regulation Of MAPK Cascade Negative Regulation Of Intracellular Transport Positive Regulation Of Cell Growth Negative Regulation Of Neuron Projection Development Regulation Of Intracellular Signal Transduction Regulation Of Proteolysis Regulation Of Cell Size Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Type B Pancreatic Cell Development Positive Regulation Of Neurofibrillary Tangle Assembly Superior Temporal Gyrus Development Negative Regulation Of Presynaptic Membrane Organization Positive Regulation Of Presynaptic Membrane Organization Response To Cytokine Negative Regulation Of Cell Projection Organization Negative Regulation Of Cell Differentiation Maintenance Of Location In Cell	Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Ubiquitination Cellular Protein Modification Process Protein Modification By Small Protein Conjugation Protein K11-linked Ubiquitination Cellular Protein Metabolic Process Protein K63-linked Ubiquitination Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Cellular Macromolecule Catabolic Process Positive Regulation Of Ligase Activity Toll-like Receptor 4 Signaling Pathway Cellular Metabolic Process Toll-like Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Pattern Recognition Receptor Signaling Pathway Proteasomal Protein Catabolic Process Innate Immune Response-activating Signal Transduction Positive Regulation Of Protein Ubiquitination Activation Of Innate Immune Response Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Innate Immune Response Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Regulation Of Metabolic Process Cellular Response To Stress Proteolysis Positive Regulation Of Protein Modification Process Regulation Of Phosphoprotein Phosphatase Activity Regulation Of Innate Immune Response Regulation Of Dephosphorylation Protein Monoubiquitination Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Protein Dephosphorylation ISG15-protein Conjugation Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of Gene Expression Cellular Response To Organic Substance Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Transferase Activity Regulation Of Catalytic Activity
Tagcloud ?			adds alleviated amount biosynthesis butyrate depleted droplet dtt encodes ergosterol glycoproteins glycosylation homeostasis kloch1 kluyveromyces lactis ld lds lipid mannosyltrasferase misfolding mobilization och1 och1p outer pba phenyl reinforce remarkably
Tagcloud (Difference) ?			adds alleviated amount biosynthesis butyrate depleted droplet dtt encodes ergosterol glycoproteins glycosylation homeostasis kloch1 kluyveromyces lactis ld lds lipid mannosyltrasferase misfolding mobilization och1 och1p outer pba phenyl reinforce remarkably
Tagcloud (Intersection) ?