PTPRF and PTPRA

Number of citations of the paper that reports this interaction (PMID 10777529)
13

Data Source:
HPRD (in vivo, two hybrid)

		PTPRF	PTPRA
Gene Name		protein tyrosine phosphatase, receptor type, F	protein tyrosine phosphatase, receptor type, A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Plasma Membrane Receptor Complex Extracellular Vesicular Exosome
	Molecular Function	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Heparin Binding Protein Complex Binding	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding
	Biological Process	Cell Adhesion Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Cell Migration Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Receptor Binding	Protein Phosphorylation Axon Guidance Insulin Receptor Signaling Pathway Peptidyl-tyrosine Dephosphorylation
Pathways			Axon guidance NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (age of onset) ( 22959728)
Protein-Protein Interactions		23 interactors: BCAR1 CAV1 CDH1 CTNNB1 FRS2 FYN GALNT1 INSR IRS1 IRS2 JUP LCK NID1 PPFIA1 PPFIA2 PPFIA3 PRPF40A PTPRA PTPRD RET SKIL TRIO ZNF512B	12 interactors: BCAR1 CALM1 FYN GABARAPL2 GRB2 KCNA2 PRKCD PTPRD PTPRF PTPRM PTPRS SRC
Entrez ID		5792	5786
HPRD ID		01552	01476
Ensembl ID		ENSG00000142949	ENSG00000132670
Uniprot IDs		P10586	B7Z2A4 P18433
PDB IDs		1LAR 2DJU 2DN7 2EDX 2EDY 2YD5 2YD8
Enriched GO Terms of Interacting Partners?		Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organonitrogen Compound Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Cellular Response To Growth Factor Stimulus Response To Organonitrogen Compound Response To Growth Factor Cellular Response To Organic Substance Response To Peptide Hormone Response To Peptide Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Hormone Stimulus Cell Adhesion Insulin Receptor Signaling Pathway Response To Hormone Cellular Response To Indole-3-methanol Epidermal Growth Factor Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Apoptotic Process Cellular Response To Insulin Stimulus Signaling Regulation Of Cell Death System Development Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Cell Communication Locomotion Regulation Of Signaling Positive Regulation Of Signal Transduction Regulation Of Cellular Component Movement Phosphatidylinositol-mediated Signaling Positive Regulation Of Glycogen Biosynthetic Process Response To Insulin Multicellular Organismal Development Regulation Of Cell Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Regulation Of Cellular Component Organization Anatomical Structure Development Organ Development Cell Migration Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Cell Motility Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cell Adhesion Signal Transduction	Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Platelet Activation Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Blood Coagulation Hemostasis Cell Communication Immune Response-regulating Signaling Pathway Fc Receptor Signaling Pathway Cellular Response To Growth Factor Stimulus Regulation Of Body Fluid Levels Immune Response-activating Cell Surface Receptor Signaling Pathway Response To Growth Factor Wound Healing Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Response To External Stimulus Cell Adhesion Response To Wounding Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Peptidyl-tyrosine Dephosphorylation Signaling Regulation Of Immune Response Nervous System Development Protein Dephosphorylation Phagocytosis T Cell Costimulation Chemotaxis Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Cellular Response To Stimulus Positive Regulation Of Immune Response Signal Transduction Cellular Response To Peptide Hormone Stimulus Cellular Response To Platelet-derived Growth Factor Stimulus Phosphate-containing Compound Metabolic Process Cellular Response To Peptide Locomotion Response To Platelet-derived Growth Factor Regulation Of Immune System Process Regulation Of Cell-cell Adhesion Cell Surface Receptor Signaling Pathway
Tagcloud ?		1r abrogated blue bombesin castration cleavage clonogenic conditioned contributions docetaxel endpoints engineered lncap medium ne neuroendocrine neuropeptides neurotensin paracrine parp pc3 phenomenon principle pthrp secretions talk thoroughly trypan twofold	aab antigens array auc autoantibodies autoantigens bead biomarkers contain curve igg luminex microarrays nappa nondiscriminating ovarian panel probed programmable ptgfr ranging retested sensitivities sera serous spauc specificity top twelve
Tagcloud (Difference) ?		1r abrogated blue bombesin castration cleavage clonogenic conditioned contributions docetaxel endpoints engineered lncap medium ne neuroendocrine neuropeptides neurotensin paracrine parp pc3 phenomenon principle pthrp secretions talk thoroughly trypan twofold	aab antigens array auc autoantibodies autoantigens bead biomarkers contain curve igg luminex microarrays nappa nondiscriminating ovarian panel probed programmable ptgfr ranging retested sensitivities sera serous spauc specificity top twelve
Tagcloud (Intersection) ?