XPO5 and NUP214

Number of citations of the paper that reports this interaction (PMID 11777942)
49

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		XPO5	NUP214
Gene Name		exportin 5	nucleoporin 214kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Nucleus Nuclear Pore Nucleoplasm Cytosol Focal Adhesion Intracellular Membrane-bounded Organelle
	Molecular Function	TRNA Binding RNA Binding Protein Binding Ran GTPase Binding Protein Transporter Activity Poly(A) RNA Binding	Transporter Activity Nucleocytoplasmic Transporter Activity Protein Binding
	Biological Process	Protein Export From Nucleus Gene Expression Gene Silencing By RNA	Mitotic Cell Cycle Carbohydrate Metabolic Process MRNA Export From Nucleus Protein Import Into Nucleus Protein Export From Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Regulation Of Cell Cycle Transmembrane Transport
Pathways		Regulatory RNA pathways MicroRNA (miRNA) biogenesis	Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport HuR stabilizes mRNA M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Regulation of mRNA stability by proteins that bind AU-rich elements Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: EEF1A1 FADD ILF3 NUP153 NUP214 RAN SMAD4 ZNF346	19 interactors: APC CLEC4G DDX19B IPO5 NFX1 NUP107 NUP88 NUPL2 NXF1 NXF2 NXF3 SMAD2 SMAD3 SMAD4 TNPO1 XPO1 XPO5 XPOT ZFP36
Entrez ID		57510	8021
HPRD ID		06385	00258
Ensembl ID		ENSG00000124571	ENSG00000126883
Uniprot IDs		Q9HAV4	P35658
PDB IDs		3A6P	2OIT 3FHC 3FMO 3FMP
Enriched GO Terms of Interacting Partners?		Nuclear Import Viral Process Viral Life Cycle Intracellular Transport Of Virus Mitotic Nuclear Envelope Disassembly Nucleocytoplasmic Transport Protein Export From Nucleus Nuclear Transport Nuclear Envelope Disassembly Gene Expression Nuclear Envelope Organization Glucose Transport Hexose Transport Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Viral Transcription RNA Biosynthetic Process Regulation Of Glucose Transport Positive Regulation Of Transcription, DNA-templated Nephrogenic Mesenchyme Morphogenesis Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Negative Regulation Of RNA Export From Nucleus Motor Neuron Apoptotic Process Viral Penetration Into Host Nucleus Nuclear Export MRNA Transport Protein Import Into Nucleus Nucleus Organization Carbohydrate Transport Positive Regulation Of Macromolecule Biosynthetic Process RNA Transport Positive Regulation Of Gene Expression Ribosomal Small Subunit Export From Nucleus Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis TRAIL-activated Apoptotic Signaling Pathway Nucleobase-containing Compound Metabolic Process RNA Localization Positive Regulation Of Cellular Biosynthetic Process Protein Import Mitotic Cell Cycle Process Cytoplasmic Transport Defense Response To Virus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein Localization To Nucleus Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process	Nucleocytoplasmic Transport Nuclear Transport Nuclear Export RNA Transport RNA Localization MRNA Transport Cytoplasmic Transport RNA Export From Nucleus Viral Process Gene Expression MRNA Export From Nucleus Establishment Of Localization In Cell Intracellular Transport Cellular Localization Protein Transport SMAD Protein Complex Assembly Establishment Of Protein Localization Gene Silencing By RNA Protein Localization Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Gene Silencing Positive Regulation Of Epithelial To Mesenchymal Transition Protein Export From Nucleus Gene Silencing By MiRNA Mitotic Nuclear Envelope Disassembly Transforming Growth Factor Beta Receptor Signaling Pathway Posttranscriptional Gene Silencing Nuclear Envelope Disassembly Positive Regulation Of Stem Cell Differentiation SMAD Protein Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Primary MiRNA Processing Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Cellular Response To Growth Factor Stimulus Viral Life Cycle Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear Envelope Organization Somatic Stem Cell Maintenance Regulation Of Transforming Growth Factor Beta2 Production Paraxial Mesoderm Morphogenesis Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Glucose Transport Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Endoderm Development Hexose Transport Embryonic Pattern Specification
Tagcloud ?			acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Difference) ?			acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Intersection) ?