CLK4 and KPNA1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CLK4	KPNA1
Gene Name		CDC-like kinase 4	karyopherin alpha 1 (importin alpha 5)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Dendrite
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity ATP Binding	Protein Binding Nuclear Localization Sequence Binding Protein Transporter Activity
	Biological Process	Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation	Regulation Of DNA Recombination Apoptotic DNA Fragmentation NLS-bearing Protein Import Into Nucleus Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Viral Process Viral Life Cycle Cytokine-mediated Signaling Pathway Positive Regulation Of Protein Import Into Nucleus Intracellular Transport Of Virus
Pathways			Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism HIV Infection Host Interactions of HIV factors Interferon Signaling Apoptotic execution phase Integration of provirus Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Influenza Infection Antiviral mechanism by IFN-stimulated genes Early Phase of HIV Life Cycle Influenza Life Cycle HIV Life Cycle Activation of DNA fragmentation factor Transport of Ribonucleoproteins into the Host Nucleus Apoptosis induced DNA fragmentation Programmed Cell Death
Drugs
Diseases
GWAS			Calcium levels ( 20705733)
Protein-Protein Interactions		10 interactors: CLASRP HSPB2 KPNA1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 RNF181 SRPK1 UBL5	32 interactors: ANP32A ANP32B BCAR3 CDKN1B CLK4 CRADD CSE1L ELAVL1 FOSL1 GOPC HDAC6 HIST2H2BE HIST3H3 IL1RAP KPNB1 LEF1 LMO4 NOSIP NUP50 NUP54 NUP62 ORC4 PAX5 RAG1 RANBP2 RUNX1T1 SKP2 SRP19 STAT1 STAT3 TAF9 UBR5
Entrez ID		57396	3836
HPRD ID		12140	02819
Ensembl ID		ENSG00000113240	ENSG00000114030
Uniprot IDs		Q9HAZ1	B3KXZ2 P52294
PDB IDs			2JDQ 3TJ3 4B18
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing	Response To Cytokine Cellular Response To Cytokine Stimulus Nucleocytoplasmic Transport Nuclear Transport Cytokine-mediated Signaling Pathway Mitotic Nuclear Envelope Disassembly Cytoplasmic Transport Nuclear Envelope Disassembly Viral Process Nucleobase-containing Compound Metabolic Process Nucleus Organization RNA Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Nitrogen Compound Metabolic Process Nuclear Envelope Organization Mitotic Cell Cycle Process Intracellular Transport Cellular Nitrogen Compound Metabolic Process Glucose Transport Regulation Of Cell Death Hexose Transport Regulation Of Cellular Protein Metabolic Process Macromolecule Biosynthetic Process Mitotic Cell Cycle Viral Life Cycle Viral Transcription Cell Death Death Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cysteine-type Endopeptidase Activity Protein Transport Response To Organic Substance Regulation Of Glucose Transport Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Metabolic Process Establishment Of Protein Localization Regulation Of Metabolic Process Negative Regulation Of Protein Metabolic Process Cellular Response To Organic Substance MRNA Transport Regulation Of Proteolysis Carbohydrate Transport RNA Metabolic Process Apoptotic Process Establishment Of Localization In Cell RNA Transport
Tagcloud ?			acids arginine auto best binds cdc34 conjugating karyopherin ligase localization lysine manipulation participates possesses promoted putative rad6 rag1 rearrangement recombinase rich spanning supported ubch2 ubch5a ubiquitin ubiquitylation undergo upstream
Tagcloud (Difference) ?			acids arginine auto best binds cdc34 conjugating karyopherin ligase localization lysine manipulation participates possesses promoted putative rad6 rag1 rearrangement recombinase rich spanning supported ubch2 ubch5a ubiquitin ubiquitylation undergo upstream
Tagcloud (Intersection) ?