RHOJ and CDC42EP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RHOJ	CDC42EP1
Gene Name		ras homolog family member J	CDC42 effector protein (Rho GTPase binding) 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Extracellular Vesicular Exosome	Cytoplasm Golgi Apparatus Plasma Membrane Focal Adhesion Actin Cytoskeleton
	Molecular Function	GTPase Activity GTP Binding	Rho GTPase Activator Activity Protein Binding GTP-Rho Binding
	Biological Process	Small GTPase Mediated Signal Transduction Rho Protein Signal Transduction Metabolic Process Regulation Of Cell Shape Actin Cytoskeleton Organization Regulation Of Small GTPase Mediated Signal Transduction Retina Vasculature Morphogenesis In Camera-type Eye	Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Rho GTPase Activity
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions		21 interactors: ACVR1 ADAMTSL4 BHLHE40 BLZF1 BMPR1B CDC42 CDC42EP1 DOCK10 DOCK8 MEOX2 PAK1 PAK2 PAK6 PARD6B SMAD2 SMAD4 SSX3 TGFBR1 TRIP10 WAS WASL	10 interactors: CDC42 DEF6 FHL3 KRTAP4-12 MAPKAP1 MDFI PLSCR1 RBPMS RHOJ RHOQ
Entrez ID		57381	11135
HPRD ID		09632	07303
Ensembl ID		ENSG00000126785	ENSG00000128283
Uniprot IDs		Q7Z513 Q9H4E5	Q00587
PDB IDs
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction Enzyme Linked Receptor Protein Signaling Pathway Cell Morphogenesis Involved In Differentiation Signal Transduction By Phosphorylation Movement Of Cell Or Subcellular Component Axonogenesis Axon Development Regulation Of Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Locomotion Regulation Of Cellular Process Axon Guidance Neuron Projection Morphogenesis Cell Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Anatomical Structure Morphogenesis Cell Morphogenesis Activin Receptor Signaling Pathway Signal Transduction Palate Development Pattern Specification Process Neuron Differentiation Regulation Of Cell Projection Assembly Fc Receptor Signaling Pathway Neuron Projection Development Immune Response-activating Cell Surface Receptor Signaling Pathway Cell Fate Commitment Signaling Cell Projection Morphogenesis Transforming Growth Factor Beta Receptor Signaling Pathway Cell Part Morphogenesis Regulation Of Signal Transduction Cell Communication Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Signal Transduction Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Tissue Development Regulation Of Nitrogen Compound Metabolic Process Chemotaxis Regulation Of Filopodium Assembly Peptidyl-threonine Phosphorylation Endocardial Cell Differentiation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Neuron Development Regulation Of Epithelial To Mesenchymal Transition Regulation Of Pathway-restricted SMAD Protein Phosphorylation Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cellular Response To Transforming Growth Factor Beta Stimulus	Regulation Of Signal Transduction Regulation Of Signaling Actin Cytoskeleton Organization Actin Filament-based Process Regulation Of Establishment Of Protein Localization Substantia Nigra Development Regulation Of Intracellular Protein Transport Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Protein Localization Regulation Of Filopodium Assembly Neural Nucleus Development Regulation Of Intracellular Signal Transduction Intracellular Signal Transduction T Cell Costimulation Regulation Of Cellular Localization Midbrain Development Regulation Of Intracellular Transport Cytoskeleton Organization Regulation Of Cell Activation Regulation Of Cell Morphogenesis Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Hair Follicle Cell Proliferation Regulation Of Cell Projection Assembly Positive Regulation Of JNK Cascade Defense Response Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Actin Filament Branching Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Submandibular Salivary Gland Formation Positive Regulation Of Cellular Metabolic Process Small GTPase Mediated Signal Transduction Regulation Of Protein Transport Regulation Of Hair Follicle Cell Proliferation Positive Regulation Of Synapse Structural Plasticity Positive Regulation Of Intracellular Protein Transport Regulation Of Cell Shape Regulation Of JNK Cascade Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Protein Import Into Nucleus Positive Regulation Of Protein Phosphorylation Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Transport Establishment Of Golgi Localization Phosphatidylserine Biosynthetic Process Regulation Of Protein Localization To Nucleus Positive Regulation Of Metalloenzyme Activity Organ Development
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