OLFML3 and CKMT2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		OLFML3	CKMT2
Gene Name		olfactomedin-like 3	creatine kinase, mitochondrial 2 (sarcomeric)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Vesicle	Mitochondrion Mitochondrial Inner Membrane
	Molecular Function		Creatine Kinase Activity ATP Binding
	Biological Process	Multicellular Organismal Development	Creatine Metabolic Process Muscle Contraction Phosphorylation Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process
Pathways			Metabolism of amino acids and derivatives Creatine metabolism
Drugs			Creatine
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		5 interactors: CKMT2 FEZ1 HSPB3 MYOC SETDB1	6 interactors: ABHD6 ELN LRIF1 OLFML3 TMED9 UNC119
Entrez ID		56944	1160
HPRD ID		14878	00425
Ensembl ID		ENSG00000116774	ENSG00000131730
Uniprot IDs		B4DNG0 M1LAK4 Q9NRN5	P17540
PDB IDs			2GL6
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Hypertrophy ERBB2-ERBB3 Signaling Pathway ERBB2 Signaling Pathway Bone Development Non-canonical Wnt Signaling Pathway Via JNK Cascade Muscle System Process Non-canonical Wnt Signaling Pathway Via MAPK Cascade Clustering Of Voltage-gated Sodium Channels Skeletal Muscle Adaptation Histone H3-K9 Trimethylation Creatine Metabolic Process Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Stress Fiber Assembly Neuronal Ion Channel Clustering Negative Regulation Of Actin Filament Bundle Assembly Negative Regulation Of Macroautophagy Establishment Of Mitochondrion Localization Regulation Of Cell Morphogenesis Regulation Of Mitochondrial Depolarization Positive Regulation Of Cell Development Histone H3-K9 Methylation Inner Cell Mass Cell Proliferation Negative Regulation Of Rho Protein Signal Transduction Positive Regulation Of Focal Adhesion Assembly Skeletal System Development Positive Regulation Of Adherens Junction Organization Peptidyl-lysine Trimethylation Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Blastocyst Growth Muscle Hypertrophy Neuron Maturation Non-canonical Wnt Signaling Pathway Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Autophagy Histone H3-K9 Modification Regulation Of Membrane Depolarization Mitochondrion Localization Negative Regulation Of Cell-matrix Adhesion	Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Caveolin-mediated Endocytosis Cytokinesis, Completion Of Separation Regulation Of Endocannabinoid Signaling Pathway
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