MAPK7 and GOLGB1

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		MAPK7	GOLGB1
Gene Name		mitogen-activated protein kinase 7	golgin B1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol PML Body	Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi Stack Cis-Golgi Network Membrane Integral Component Of Membrane
	Molecular Function	MAP Kinase Activity Protein Binding ATP Binding Mitogen-activated Protein Kinase Binding	Protein Binding Poly(A) RNA Binding
	Biological Process	Toll-like Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Cell Cycle Signal Transduction Peptidyl-serine Phosphorylation CAMP-mediated Signaling Cell Differentiation Negative Regulation Of CAMP Catabolic Process Negative Regulation Of Heterotypic Cell-cell Adhesion Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 3 Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Toll-like Receptor 10 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Innate Immune Response Regulation Of Angiogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Inflammatory Response Positive Regulation Of Protein Metabolic Process Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Stress-activated MAPK Cascade Negative Regulation Of NFAT Protein Import Into Nucleus Negative Regulation Of Response To Cytokine Stimulus Cellular Response To Hydrogen Peroxide Cellular Response To Growth Factor Stimulus Cellular Response To Laminar Fluid Shear Stress Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Endothelial Cell Apoptotic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Golgi Organization
Pathways		Signaling by GPCR Toll Like Receptor 7/8 (TLR7/8) Cascade Cellular Senescence ERKs are inactivated Toll Like Receptor TLR6:TLR2 Cascade Toll Like Receptor TLR1:TLR2 Cascade Activated TLR4 signalling MyD88 cascade initiated on plasma membrane Toll Like Receptor 5 (TLR5) Cascade Gastrin-CREB signalling pathway via PKC and MAPK MyD88 dependent cascade initiated on endosome MyD88:Mal cascade initiated on plasma membrane TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation Toll Like Receptor 9 (TLR9) Cascade ERK/MAPK targets Innate Immune System Signalling to ERK5 ERKs are inactivated Signalling by NGF TRIF-mediated TLR3/TLR4 signaling MAP kinase activation in TLR cascade Senescence-Associated Secretory Phenotype (SASP) NGF signalling via TRKA from the plasma membrane MyD88-independent cascade Toll Like Receptor 2 (TLR2) Cascade Toll-Like Receptors Cascades Toll Like Receptor 10 (TLR10) Cascade Toll Like Receptor 3 (TLR3) Cascade ERK/MAPK targets Toll Like Receptor 4 (TLR4) Cascade MAPK targets/ Nuclear events mediated by MAP kinases Nuclear Events (kinase and transcription factor activation)
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: ACTN4 APP C5orf30 EGLN3 ELK4 ETS1 FGF21 FOS GJA1 GOLGB1 MAP2K5 MEF2A MEF2C MEF2D MYC NFE2L2 NR1I2 PRKCZ PTPRR RAF1 RXRA SGK1 SH2D2A UBE2C YWHAB YWHAE ZBED6CL	15 interactors: ACBD3 BRMS1 CAV2 ITSN2 KIAA0368 KIAA1377 MAPK7 NDUFA1 PFN2 SKIL SLC2A3 SREBF2 UBE2I USO1 VTI1B
Entrez ID		5598	2804
HPRD ID		03952	03933
Ensembl ID		ENSG00000166484	ENSG00000173230
Uniprot IDs		Q13164	F1T0J2 Q14789
PDB IDs		2Q8Y 4B99 4IC7 4IC8
Enriched GO Terms of Interacting Partners?		Response To Fluid Shear Stress Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Cellular Metabolic Process Apoptotic Process Programmed Cell Death Cellular Response To Growth Factor Stimulus Cell Death Death Positive Regulation Of Metabolic Process Response To Growth Factor Negative Regulation Of Cellular Metabolic Process Regulation Of Apoptotic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Fluid Shear Stress Regulation Of Cell Death Positive Regulation Of Protein Metabolic Process Regulation Of Metabolic Process MAPK Cascade Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Organic Substance Positive Regulation Of Behavioral Fear Response Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Regulation Of Phosphorus Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Organic Substance Positive Regulation Of Macromolecule Biosynthetic Process Signal Transduction By Phosphorylation Positive Regulation Of Gene Expression Regulation Of Cellular Component Organization Cellular Response To Stimulus Positive Regulation Of Cellular Biosynthetic Process Response To Stress Positive Regulation Of Transcription, DNA-templated Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Neurotrophin Signaling Pathway Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Cell Proliferation Cardiac Conduction Regulation Of Signal Transduction Cardiovascular System Development Regulation Of RNA Metabolic Process Regulation Of MAPK Cascade Learning Or Memory Anatomical Structure Morphogenesis Signal Transduction Response To Hormone	Vesicle Fusion Cellular Response To Laminar Fluid Shear Stress Vesicle Fusion With Golgi Apparatus Organelle Fusion Vesicle Docking Membrane Docking Cellular Response To Fluid Shear Stress Response To Laminar Fluid Shear Stress Membrane Fusion Response To Fluid Shear Stress Vesicle Organization Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Lipid Transport By Negative Regulation Of Transcription From RNA Polymerase II Promoter Golgi Vesicle Docking Negative Regulation Of CAMP Catabolic Process Organelle Organization ER To Golgi Vesicle-mediated Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Anoikis Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Positive Regulation Of Metabolic Process Negative Regulation Of Cholesterol Efflux Skeletal Muscle Tissue Development Negative Regulation Of Ruffle Assembly Skeletal Muscle Organ Development Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of NFAT Protein Import Into Nucleus Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Golgi To Vacuole Transport Negative Regulation Of Heterotypic Cell-cell Adhesion Caveola Assembly Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Response To Transforming Growth Factor Beta Positive Regulation Of Signal Transduction Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Cholesterol Transport Membrane Raft Assembly
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