WSB2 and CSF3R

Number of citations of the paper that reports this interaction (PMID 17001306)
3

Data Source:
BioGRID (affinity chromatography technology, imaging technique, protein complementation assay)

		WSB2	CSF3R
Gene Name		WD repeat and SOCS box containing 2	colony stimulating factor 3 receptor (granulocyte)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Extracellular Region Integral Component Of Plasma Membrane
	Molecular Function		Receptor Activity Cytokine Receptor Activity Protein Binding
	Biological Process	Protein Ubiquitination Intracellular Signal Transduction	Defense Response Cell Adhesion Signal Transduction Cytokine-mediated Signaling Pathway Neutrophil Chemotaxis Amelogenesis
Pathways
Drugs			Pegfilgrastim Filgrastim
Diseases
GWAS
Protein-Protein Interactions		3 interactors: CSF3R EZH2 RPN1	19 interactors: CISH CSF3 ELANE FTH1 GRB2 HCK INPP5D JAK1 JAK2 LCK LYN PLA2G1B PTPN11 SHC1 SOCS3 STAT3 SYK WSB1 WSB2
Entrez ID		55884	1441
HPRD ID		18305	00737
Ensembl ID		ENSG00000176871	ENSG00000119535
Uniprot IDs		B4DIE6 B4DPV6 Q9NYS7	Q99062
PDB IDs			1AZ7 2D9Q
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Satellite Cell Maintenance Involved In Skeletal Muscle Regeneration G1 To G0 Transition Negative Regulation Of Epidermal Cell Differentiation Histone H3-K27 Methylation Protein Localization To Organelle Protein Localization To Chromatin	Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Immune Response Leukocyte Migration Regulation Of Immune Response Response To Peptide Hormone Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Organonitrogen Compound Response To Peptide Regulation Of Immune System Process Intracellular Signal Transduction Cellular Response To Hormone Stimulus Cell Migration Enzyme Linked Receptor Protein Signaling Pathway Peptidyl-tyrosine Autophosphorylation Cell Motility Immune System Process Defense Response Innate Immune Response Regulation Of Cell Proliferation Movement Of Cell Or Subcellular Component JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Response To Organonitrogen Compound Response To Organic Substance Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Locomotion Response To Hormone Regulation Of Signal Transduction Regulation Of Phosphorylation Regulation Of Protein Phosphorylation Cellular Response To Organic Substance Regulation Of Phosphorus Metabolic Process Response To Growth Hormone Regulation Of Signaling Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Immune System Process Positive Regulation Of Signal Transduction JAK-STAT Cascade Blood Coagulation Hemostasis Regulation Of Intracellular Signal Transduction Signal Transduction Cytokine-mediated Signaling Pathway Fc Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Peptidyl-tyrosine Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Response To Stimulus
Tagcloud ?			1155insttgtc accuracy allele asxl1 calr carried cml cnl criteria diagnostic differential gammopathy jak2 leukocytosis mgus monoclonal mutations neutrophilic observe protocol retrospectively reviewed sequenced setbp1 significance suspected twelve uncertain v617f
Tagcloud (Difference) ?			1155insttgtc accuracy allele asxl1 calr carried cml cnl criteria diagnostic differential gammopathy jak2 leukocytosis mgus monoclonal mutations neutrophilic observe protocol retrospectively reviewed sequenced setbp1 significance suspected twelve uncertain v617f
Tagcloud (Intersection) ?